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Featured researches published by Murray Allen.


Journal of Hand Surgery (European Volume) | 2015

Wrist Ganglion Treatment: Systematic Review and Meta-Analysis

Linden Head; John Robert Gencarelli; Murray Allen; Kirsty U. Boyd

PURPOSE To review the clinical outcomes of treatment for adult wrist ganglions and to conduct a meta-analysis comparing the 2 most common options: open surgical excision and aspiration. METHODS The review methodology was registered with PROSPERO. We performed a systematic search of MEDLINE and EMBASE for articles published between 1990 and 2013. Included studies reported treatment outcomes of adult wrist ganglions. Two independent reviewers performed screening and data extraction. We evaluated the methodological quality of randomized controlled trials (RCT) and cohort studies using the Cochrane Handbook for Systematic Reviews and the Newcastle-Ottawa Scale, respectively; Grading of Recommendations, Assessment, Development, and Evaluation was used to evaluate the quality of evidence. RESULTS A total of 753 abstracts were identified and screened; 112 full-text articles were reviewed and 35 studies (including 2,239 ganglions) met inclusion criteria for data extraction and qualitative synthesis. Six studies met criteria for meta-analysis, including 2 RCTs and 4 cohort studies. In RCTs surgical excision was associated with a 76% reduction in recurrence compared with aspiration. Randomized controlled trial quality was moderate. In cohort studies surgical excision was associated with a 58% reduction in recurrence compared with aspiration. Cohort study quality was very low. In cohort studies aspiration was not associated with a significant reduction in recurrence compared with reassurance. Across all studies mean recurrence for arthroscopic surgical excision (studies, 11; ganglions, 512), open surgical excision (studies, 14; ganglions, 809), and aspiration (studies, 12; ganglions, 489) was 6%, 21%, and 59%, respectively. Mean complication rate for arthroscopic surgical excision (studies, 6; ganglions, 221), open surgical excision (studies, 6; ganglions, 341), and aspiration (studies, 3; ganglions, 134) was 4%, 14%, and 3%, respectively. CONCLUSIONS Open surgical excision offers significantly lower chance of recurrence compared with aspiration in the treatment of wrist ganglions. Arthroscopic excision has yielded promising outcomes but data from comparative trials are limited and have not demonstrated its superiority. Further RCTs are needed to increase confidence in the estimate of effect and to compare complications and recovery. TYPE OF STUDY/LEVEL OF EVIDENCE Therapeutic I.


Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology | 2013

Management of the radial forearm free flap donor site using a topically applied tissue expansion device

James P. Bonaparte; Martin Corsten; Michael J Odell; Michael K. Gupta; Murray Allen; Darren Tse

BACKGROUND The purpose of this study was to prospectively assess clinical outcomes in patients undergoing a new method of donor site management for radial forearm free flaps. METHODS 177 patients underwent reconstruction of ablative defects of the head and neck using a radial forearm free-flap. All patients had topical tissue expansion tapes applied to their forearms preoperatively. Closure rates, healing time and complications associated with the technique were assessed. RESULTS Ninety-five percent of patients had their donor sites closed primarily with a locally harvested full thickness skin graft. Complications related to the tissue expansion device included a loss of device adhesion (19.3%) requiring reapplication and minor pruritic reactions (4.1%). CONCLUSIONS This system of donor site management has resulted in a significant reduction in the requirement of a split thickness skin graft for coverage of the donor site in a radial forearm free flap without any significant economic cost or patient morbidity.


Clinical Otolaryngology | 2011

Cost-effectiveness of a topically applied pre-operative tissue expansion device for radial forearm free flaps: a cohort study.

James P. Bonaparte; M. Corsten; Murray Allen

Clin. Otolaryngol. 2011, 36, 345–351


Journal of Craniofacial Surgery | 2016

The Use of Neuronavigation as an Adjunct in Facial Reconstructive Surgery.

Zach Zhang; Daniel A Peters; Murray Allen; Kirsty U. Boyd

Neuronavigation, a ubiquitous tool used in neurosurgery, is rarely used in maxillofacial reconstructive surgery despite it offering many advantages without any disadvantage to the patient. The present report describes one patient with complex gun-shot wound facial injury and one patient with a rare malignant peripheral nerve sheath tumor involving the skull base, in which neuronavigation was used to improve the accuracy of bony reduction and minimize surgical invasiveness. Although neuronavigation is not necessary for all maxillofacial surgery, it can be a useful adjunct in complex maxillofacial reconstruction and maxillofacial tumor resection.


Plastic Surgery Case Studies | 2015

Hemipelvis Reconstruction in Trauma: A Case Report and Literature Review

Grayson Roumeliotis; Ashley Ignatiuk; Allan Sl Liew; Murray Allen; Kirsty U. Boyd

Composite reconstruction of the pelvis in the setting of trauma is challenging. In addition to coverage and containment of the abdominal viscera, recreating a robust sitting surface is critical. However, there is a paucity of literature to guide the reconstructive surgeon. The authors present a case of traumatic hemipelvectomy, and describe their application of the ‘spare-parts’ concept to successfully reconstruct the bony pelvis and provide soft tissue coverage.


The Annals of Thoracic Surgery | 2000

The stomach as a microvascularly augmented flap for esophageal replacement

Azim Valji; Donna E. Maziak; Murray Allen; Farid M. Shamji

We present a case of difficult esophageal reconstruction after total esophagectomy for iatrogenic perforation in a diseased esophagus. The stomach was used for esophageal reconstruction as a retrosternal microvascularly augmented flap; the vascular supply to the stomach had been interrupted during previous abdominal operations. The blood supply to the stomach conduit was restored by separate arterial and venous anastomosis between the right internal thoracic vessels and the left gastric vessels.


Journal of otolaryngology - head & neck surgery | 2009

Reduction of donor site morbidity in the radial forearm free flap by use of topical tissue expanders.

Michael K. Gupta; Murray Allen; Martin Corsten


Obesity Research | 2004

Adipogenic and Antiapoptotic Protein Levels in Human Adipose Stromal Cells after Weight Loss

Denise Aubin; AnneMarie Gagnon; Laura Grunder; Robert Dent; Murray Allen; Alexander Sorisky


Journal of otolaryngology - head & neck surgery | 2011

Cosmetic and functional outcomes after preoperative tissue expansion of radial forearm free flap donor sites: a cohort study.

James P. Bonaparte; Martin Corsten; Murray Allen


Journal of otolaryngology - head & neck surgery | 2011

Healing time of radial forearm free flap donor sites after preoperative tissue expansion: randomized controlled trial.

James P. Bonaparte; Martin Corsten; Murray Allen

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