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Dive into the research topics where N. Akiyama is active.

Publication


Featured researches published by N. Akiyama.


Advances in Experimental Medicine and Biology | 2003

Molecular Organizations of Myofibrils of Skeletal Muscle Studied by Atomic Force Microscopy

Takenori Yamada; Yuki Kunioka; Jun’ichi Wakayama; Momoko Aimi; Yusuke Noguchi; N. Akiyama; Taisuke Kayamori

By applying AFM technology, we studied mechanical characteristics of myofibrils of skeletal muscle. The obtained results indicate that (1) the Z-band is the most rigid sarcomere component stabilizing the myofibril structures, (2) various filamentous components are inter-connected in sarcomere with sufficient mechanical strength to support the contractile force, and (3) the molecular structure of the overlap region between actin and myosin filaments is anisotropic. In any case the present studies clearly indicate that the AFM technique is a powerful tool to investigate the mechanical characteristics of sarcomere structure of muscle fiber.


Seibutsu Butsuri | 2007

1P145 Effects of osmotic compression on the actomyosin filament lattice in single skeletal myofibrils examined by atomic force microscopy(Muscle-muscle proteins and contraction,Poster Presentations)

Hirotaka Fujita; Daisuke Miyashiro; Atsushi Hamazaki; N. Akiyama; Y. Kunioka; T. Yamada


Seibutsu Butsuri | 2006

1P223 Effects of BDM on the transverse stiffness of muscle fibers and myofibrils studied by atomic force microscopy(8. Muscle contraction and muscle protein,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

N. Akiyama; Daisuke Miyashiro; Y. Kunioka; T. Yamada


Seibutsu Butsuri | 2006

1P224 The diameter and its changes of single skeletal myofibrils examined by atomic force microscopy(8. Muscle contraction and muscle protein,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

Daisuke Miyashiro; Hirotaka Fujita; Atsushi Hamazaki; N. Akiyama; Y. Kunioka; T. Yamada


Proceedings of Annual Meeting of the Physiological Society of Japan Proceedings of Annual Meeting of the Physiological Society of Japan | 2006

Diameter measurements of single skeletal myofibrils: AFM studies

Daisuke Miyashiro; Atsushi Hamazaki; Hirotaka Fujita; N. Akiyama; Yuki Kunioka; Takenori Yamada


Seibutsu Butsuri | 2005

1P143 Diameter measurements of single skeletal myofibrils by use of Atomic Force Microscope

Atsushi Hamazaki; Daisuke Miyashiro; N. Akiyama; Y. Kunioka; T. Yamada


Seibutsu Butsuri | 2004

1P172 Effects of proteolytic treatments on the molecular structures in cardiac and skeletal myofibrils studied by AFM and SDS-PAGE

N. Akiyama; Yoshiki Ohnuki; Yasutake Saeki; Y. Kunioka; T. Yamada


Seibutsu Butsuri | 2003

Structural analysis of cardiac and skeletal muscle myofibrils studied by atomic force microscopy

N. Akiyama; Yoshiki Ohnuki; Yasutake Saeki; Y. Kunioka; T. Yamada


Seibutsu Butsuri | 2003

Selective molecular ruptures in skeletal muscle myofibrils studied by atomic force microscopy

T. Kayamori; N. Miyake; Atsushi Hamazaki; N. Akiyama; Y. Kunioka; T. Yamada


Seibutsu Butsuri | 2002

3L1115 Effects of proteolytic digestion on the transverse stiffness of cardiac and skeletal myofibrils : AFM studies

N. Akiyama; Yoshiki Ohnuki; Yasutake Saeki; Y. Kunioka; T. Yamada

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T. Yamada

Tokyo University of Science

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Y. Kunioka

Tokyo University of Science

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