N. G. Luk'yanenko

Cyclic thioureas (review)

Literature data on methods for the synthesis of cyclic thioureas and their physicochemical properties and transformations are correlated.

Polymer-supported aza-15-crown-5 as effective catalyst for phase-transfer reactions

SummaryImmobilized aza-15-crown-5 were prepared by the reaction of chloromethylated polystyrene resin with N-(2-hydroxyethyl)-aza-15-crown-5. These polymer-supported crowns were very effective catalysts of nucleophilic substitution reactions carried out under the conditions of the two-phase (L-S) or three-phase (L-S-L) catalysis.

Macroheterocycles. 27. Amidomethylation of benzo-crown ethers

The synthesis of some novel benzo-crown ethers by α-amidomethylation is described.

Macroheterocycles. 25. Convenient synthesis of crown-compounds with thiocarbamide groups

The reaction of polyoxyethylene diamines with polyoxyethylene diisothiocyanates leads to new crowns with thiocarbamide groups having 13- to 34-membered rings. Binuclear crown compounds with thiocarbamide groups are prepared by the reaction of polyoxyethylene diisothiocyanates with aza-15-crown-5.

Acylation of aza crown ethers with N-substituted isophthalimides

Acylated aza crown ethers containing fragments of N-substituted phthalamic acids in the side chain were obtained by the reaction of monoaza-15-crown-5, monoaza-18-crown-6, and diaza-18-crown-6 with N-substituted isophthalimides.

Psychotropic properties of aza-15-crown-5 derivatives with pharmacophoric groups

i. A. B. Nikonova, N. V. Makarova, and S. A. Titov, Zh. Vyssh. Nervn. Deyat., 37, No. 3, 570-572 (1987). 2. S. A. Titov, O. G. Voskresenskaya, I. Yu. Shamakina, and I. P. Ashmarin, Dokl. Akad. Nauk SSSR, 264, Na. 5, 1269-1272 (1982). 3.

Mass spectra of binuclear crown ethers

. A. Titov, I. Yu. Shamakina, and I. P. Ashmarin, Byull. Eksp. Biol., 45, No. 2, 31-33 (1983).

Macroheterocycles. 32. Homolytic dehydrodimerization of crown ethers

. I.~Yu. Shamakina, S. A. Titov, A. B. Nikonova, and O. G. Voskresenskaya, Zh. Vyssh. Nervn. Deyat., 37, No. i, 100-105 (1987). 5. J. P. H. Burbach and J. L. M. Leboille, J. Biol. Chem., 258, No. 3, 1487-1494 (1983). 6. J. P. H. Burbach, G. L. Kovacs, D. de Wied, et al., Science, 221, No. 4617, 1310-1312 (1983).

Macroheterocycles. 31. Binuclear crown ethers based on 1,1,2,2-tetrahydroxymethanylethane

The mass-spectral analytical characteristics of binuclear crown ethers were established. The determining role of 1,5- and 1,4-C-H...O transannular interactions in the realization of rearrangement processes during fragmentation were ascertained.

Crown ethers bound to sulfanilamide preparations

The corresponding bis(crown ethers), as well as phenyl- and hydroxy-substituted crown ethers, were obtained by homolytic dehydrodimerization of 12-crown-4, 15-crown-5, and 18-crown-6 in benzene or water.