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Dive into the research topics where N Giannessi is active.

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Featured researches published by N Giannessi.


Journal of Endocrinological Investigation | 1990

GHRH-test in short children with "non classic" GH deficiency. A comparison with "classic" GH deficiency and short normal stature.

Giuseppe Saggese; G Cesaretti; N Giannessi; L Cinquanta; C Bracaloni; C. Cioni; G Di Spigno; R. Di Porto

In this study GHRH-test has been performed (2 μg/Kg of an iv bolus of GHRH 1–44) sampling for GH measurement every 15 min over 2 hours in three groups of short children. Group 1 consisted of 10 subjects with classic GH deficiency (CGHD): GH response < 10 ng/ml to two conventional tests and 24-h mean GH concentration (MGHC) < 3 ng/ml; group 2 consisted of 16 subjects with non-classic GH deficiency (NCGHD): response > 10 ng/ml to at least one conventional test and MGHC < 3 ng/ml; group 3 consisted of 18 subjects with short normal stature: GH response > 10 ng/ml to at least one conventional test and MGHC >3 ng/ml. GH peak and area under the curve (AUC) values were significantly lower in group 1 than groups 2 and 3 and in group 2 than group 3. GH peak and AUC values statistically correlated with height, height velocity, bone age/chronological age ratio and MGHC. Six children in group 1,14 children in group 2 and all 18 children in group 3 showed after GHRH a GH peak > 10 ng/ml and were considered as ‘responders’. Considering only the responders, GH peak and AUC values were significantly lower in group 1 than groups 2 and 3 and in group 2 than group 3. In conclusion, our data have shown that 87% of children with NCGHD responded to a single bolus of GHRH with an increase in GH levels > 10 ng/ml and that their responses were intermediate compared to those of CGHD and short normal subjects.


The Journal of Clinical Endocrinology and Metabolism | 1992

Stimulated growth-hormone (GH) secretion in children with delays in pubertal development before and after the onset of puberty - relationship with peripheral plasma GH-releasing hormone and somatostatin levels

Giuseppe Saggese; G Cesaretti; N Giannessi; C Bracaloni; L Cinquanta; C. Cioni


MINERVA Pediatrica | 1991

Endocrine study in the Prader-Willi syndrome. Apropos of 5 cases

L Calisti; N Giannessi; G Cesaretti; Giuseppe Saggese


Hormone Research in Paediatrics | 1991

Evaluation of 24-Hour Growth Hormone Spontaneous Secretion: Comparison with a Nocturnal and Diurnal 12-Hour Study

Giuseppe Saggese; G Cesaretti; L Cinquanta; N Giannessi; C Bracaloni; G Di Spigno; C. Cioni


MINERVA Pediatrica | 1993

Discitis in children. Report of two cases

L Calisti; N Giannessi; Crespin L; Giuseppe Saggese


MINERVA Pediatrica | 1993

Correlation between growth velocity and hematologic levels of somatomedin C during the treatment with growth hormones (GH) in subjects with "classic" and "non-classic" deficits of GH

Giuseppe Saggese; G Cesaretti; C. Cioni; C Bracaloni; N Giannessi; L Cinquanta


RIVISTA ITALIANA DI PEDIATRIA | 1990

Valutazione della secrezione dell'ormone della crescita durante 24 ore nella sindrome di Turner

Giuseppe Saggese; G Cesaretti; C. Cioni; C Bracaloni; N Giannessi; G Di Spigno


Archive | 1989

Plasma zinc in short statured children

N Giannessi; G Cesaretti; C Bracaloni; L Cinqualta; M Pucciarelli; Giuseppe Saggese


MINERVA Pediatrica | 1989

Selective deficit of IgA and infantile rheumatoid arthritis. Case reports

G Cesaretti; L Calisti; N Giannessi; G Petrillo; C Fusaro; Giuseppe Saggese


Journal of Endocrinological Investigation | 1989

Growth hormone treatment in non-classical GH deficient children.

Giuseppe Saggese; G Cesaretti; G Di Spigno; N Giannessi; C Bracaloni; L Cinquanta; C. Cioni

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