N. N. Magdesieva

Synthesis of benzo[b]selenophene and its methyl homologs

A method for the synthesis of benzo[b]selenophenes was perfected. 3-Oxo-2,3-dihydrobenzo[b]selenophene and 2-methyl-3-oxo-2,3-dihydrobenzo[b]selenophene exist only in the keto form. 3-Methylbenzo[b]selenophene was obtained by the reaction of 3-oxo-2,3-dihydrobenzo[b]selenophene with methylmagnesium iodide. Metallation of benzo[b]selenophene with butyllithium proceeds at the 2 position of the selenophene ring.

Chemistry of selenophene

The synthesis of a number of β-diketones and 3, 5-disubstituted pyrazoles with 3-selenienyl radicals has been described.

Synthesis of tetrasubstituted furans

The synthesis of tetrasubstituted furans has been effected by the reaction of selenonium diacylmethylides with dimethyl acetylenedicarboxylate.

Kinetics of the solvolysis of ?-bromo ketones of the thiophene and selenophene series in aqueous ethanol

A comparative study of the kinetics of the solvolysis of α-bromo ketones of the selenophene, thiophene, and benzene series in 50% ethanol at 55, 70, and 80°C has been performed. The activation parameters of the reactions have been determined and it has been shown that solvolysis takes place mainly by an SN2 mechanism. The rate of solvolysis rises in the sequence selenophene → thiophene → benzene.

Synthesis of 2,4-disubstituted 2,3-dihydro-1H-1,5-benzodiazepines of the 1,3-indanedione series

Abstract2,4-Disubstituted 2,3-dihydro-1H-1,5-benzodiazepines were synthesized by reacting o-phenylenediamine with α,β-unsaturated ketones of the indanedione series.

Chemistry of benzo[b]selenophene: V. Mercuration of benzo[b]selenophene

The mercuration of benzo[b]selenophene by mercuric acetate proceeds to form the 2-mercuri derivative, while 2-methyl- and 3-methylbenzo[b]selenophenes give 3-mercuri-2-methyl and 2-mercuri-3-methyl derivatives of benzo[b]selenophene, respectively. The corresponding deutero derivatives of benzo[b]selenophene were obtained by substitution of the chloromercuri group by iodine with subsequent reduction by zinc in deuterated acetic acid.

Synthesis of 1,3-dihydrobenzo[c]selenophene

Abstract1,3-Dihydrobenzo[c]selenophene was synthesized from ω, ω′-dibromo-o-xylene and sodium selenide.

Synthesis of ?-amino alcohols of the selenophene series

Abstract(2-Selenienyl)ethanolamines were synthesized by the reduction of the corresponding amino ketones and isonitroso ketones.

DIE SYNTH. VON ALPHA‐AMINOALKOHOLEN DER SELENOPHENREIHE

Die bei der Umsetzung der Selenophenketone (I) mit Butylnitrit (II) in Gegenwart von Natriumathylat entstehenden Keto-oxime (III) lassen sich mit Lithiumaluminiumhydrid zu den Aminoalkoholen (IV) reduzieren.

Synthesis of substituted β-(2-selenienyl)-ethylamines

Substituted β-(2-selenienyl)ethylamines were synthesized by the reduction of the corresponding α,β-unsaturated nitro compounds. 2-(ω-Nitrovinyl)selenophene was alkoxylated and aminated.