N. Relihan

Rapid on-site evaluation of axillary fine-needle aspiration cytology in breast cancer

Axillary ultrasonography (AUS) and fine‐needle aspiration cytology (FNAC) can establish axillary lymph node status before surgery, although this technique is hampered by poor adequacy rates. To achieve consistently high rates of FNAC adequacy, rapid on‐site evaluation (ROSE) of FNAC samples was introduced.

Unusual paraneoplastic syndromes of breast carcinoma: a combination of cerebellar degeneration and Lambert-Eaton Myasthenic Syndrome

IntroductionParaneoplastic neurological disorders are rare complications of breast carcinoma. Lambert–Eaton Myasthenic Syndrome (LEMS) is most commonly associated with small cell lung cancer. However, a combination of LEMS and subacute cerebellar degeneration as paraneoplastic syndromes is extremely rare, and has never been described in association with breast cancer.CaseWe report for the first time an unusual association of LEMS and paraneoplastic subacute cerebellar degeneration with breast carcinoma.ConclusionIn patients with atypical LEMS, when there is no evidence of respiratory malignancy, breast cancer should be included in the differential diagnosis.

Completion lymphadenectomy following positive sentinel node biopsy may not be justified in early stage breast cancer

ConclusionWhile SLNB accurately predicts nodal basin status, the incidence of nodal metastases in patients with early stage Tl cancers at ALND following a positive SLNB is 8%. The data suggest that patients with early stage breast cancer may not require completion lymphadenectomy, regardless of SLN positivity.