N Singh

Diagnostic Dilemma in Typhoid Fever-Real Time PCR, Need of the Hour

Typhoid fever caused by Salmonella typhi is an important public health problem. The World Health Organization (WHO) estimate for annual global incidence of typhoid fever, is about 21 million cases and 216,000 deaths every year (Crump et al., 2004). Enteric fever is still a common disease in many parts of the world where supply of clean water is limited. In countries such as India, Nepal, Pakistan, Indonesia and parts of sub-Saharan Africa, typhoid is still a substantial public health problem (Bhan, 2005). In these areas, as febrile disease is common, accurate diagnosis is the need of hour, particularly as antimicrobial resistance is emerging (Chau et al., 2007). International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 9 (2017) pp. 3012-3017 Journal homepage: http://www.ijcmas.com