N. Suryakiran

Synthesis of Chloroesters by the Cleavage of Cyclic and Acyclic Ethers using La(NO3)3 · 6H2O as a Mild and Efficient Catalyst under Solvent‐Free Conditions

Abstract A mild and an efficient synthesis of chloroesters is described by the reaction of cyclic and acyclic ethers with acid chlorides in the presence of a catalytic amount of La(NO3)3 · 6H2O under solvent‐free conditions, affording the corresponding chloroesters in excellent yields.

Lanthanum(III) Nitrate Hexahydrate: A Versatile Reagent for the Synthesis of Bis(indolyl) Methanes under Solvent‐Free Conditions

Abstract A mild and efficient synthesis of bis(indolyl) methanes by the reaction of indoles with various aldehydes at room temperature in the presence of a catalytic amount of a La(NO3)3 · 6H2O afforded the corresponding bis(indolyl) methanes in excellent yields under solvent‐free conditions.

Mild and Highly Efficient Stereoselective Synthesis of 2,3‐Unsaturated Glycopyranosides using La(NO3)3 · 6H2O as a Catalyst: Ferrier Rearrangement

Abstract A mild and highly efficient stereoselective reaction of 3,4,6‐tri‐O‐acetyl‐d‐glucal with a variety of nucleophiles, viz. alcohols, phenols, thiols, thiophenols, and allyl trimethyl silane (TMS), in the presence of 5 mol% of lanthanum(III) nitrate hexahydrate under solvent‐free conditions yielded the corresponding 2,3‐unsaturated glycopyranosides (pseudoglycals) in excellent yields.

Facile tert‐Butoxycarbonylation of Alcohols, Phenols, and Amines using BiCl3 as a Mild and Efficient Catalyst

Abstract Facile tert‐butoxycarbonylation of alcohols, phenols, and amines is described by treatment of alcohols, phenols, and amines with di‐tert‐butyl dicarbonate in the presence of a catalytic amount of bismuth(III) chloride, a mild and efficient catalyst, at room temperature in excellent yields.

Efficient synthesis of β-hydroxy-sulfones via opening of epoxides with sodium sulfinates in ionic liquid [TPA][Pro]

An efficient synthesis of β-hydroxy-sulfones is described by the reaction of sodium sulfinates with epoxides in ionic liquid [TPA][Pro] as an efficient reaction medium to afford the corresponding β-hydroxy-sulfones in excellent yields.

Mild and Efficient Chemoselective Synthesis of Acetals and Geminal Diacetates (Acylals) from Aldehydes using Lanthanum(III) Nitrate Hexahydrate

Abstract A mild and efficient chemoselective method has been developed for the preparation of acetals and gem‐diacetates in good to excellent yields through a reaction of aldehydes with ethlyleneglycol or acetic anhydride using catalytic amounts of lanthanum(III) nitrate hexahydrate as a catalyst under solvent‐free conditions.

Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea

The sponge Dysidea herbacea was collected from the Mandapam Coast, Tamilnadu, India. Isolated gram quantities of hydroxylated polybrominated diphenyl ether (HO-PBDE) and semi-synthesized a series of new PBDEs derivatives and tested them for antibacterial and cytotoxic activities.

Lanthanum(III) nitrate hexahydrate catalyzed chemoselective thioacetalization of aldehydes

A wide variety of cyclic and acyclic dithioacetals have been prepared chemoselectively from their corresponding aldehydes with 1,3-dithiol and ethanethiol using catalytic amounts of lanthanum(III) nitrate hexahydrate as a catalyst at room temperature. †IICT Communication # 061103.

Synthesis of N-homobicyclic dideoxynucleoside analogues

Syntheses of six N-homobicyclic dideoxynucleoside analogues are described. The reaction of mannose diacetonide with trimethylsulfoxonium iodide gave a mixture of diastereomeric hydroxymethyl mannose diacetonides in a ratio of 2:5, which was separated by fractional crystallization. The two stereoisomers were converted to bicyclic furanolactols each of which was coupled with three nucleoside bases. Further debenzylations gave the six target N-homobicyclic dideoxynucleosides.