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Dive into the research topics where Nachimuthu Soundararajan is active.

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Featured researches published by Nachimuthu Soundararajan.


Tetrahedron Letters | 1994

Improved synthesis of aryl 1,1-dimethylpropargyl ethers

Jollie D. Godfrey; Richard H. Mueller; Thomas C. Sedergran; Nachimuthu Soundararajan; Vincent J. Colandrea

Abstract An efficient, general, and practical synthesis of aryl 1,1-dimethylpropargyl ethers has been developed.


Tetrahedron Letters | 2002

A practical synthesis of chloromethyl esters from acid chlorides and trioxane or paraformaldehyde promoted by zirconium tetrachloride

Boguslaw Mudryk; Shanthi Rajaraman; Nachimuthu Soundararajan

A practical synthesis of chloromethyl esters from acid chlorides and trioxane or paraformaldehyde using zirconium tetrachloride as the Lewis acid has been demonstrated. The new procedure is highly chemoselective and applies to a variety of acid chlorides.


Archive | 2005

Prodrugs of piperazine and substituted piperidine antiviral agents

Yasutsugu Ueda; Timothy P. Connolly; John F. Kadow; Nicholas A. Meanwell; Tao Wang; Chung-Pin H. Chen; Kap-Sun Yeung; Zhongxing Zhang; David K. Leahy; Shawn K. Pack; Nachimuthu Soundararajan; Pierre Sirard; Kathia Levesque; Dominique Thoraval


Archive | 2003

Process for the preparation of antiviral 7-azaindole derivatives

Serge Benoit; Stephane Gingras; Nachimuthu Soundararajan


Archive | 2006

Process for preparing triazole substituted azaindoleoxoacetic piperazine derivatives and novel salt forms produced therein

Nachimuthu Soundararajan; Yuping Qiu; Wenhao Hu; David R. Kronenthal; Pierre Sirard; Jean Lajeunesse; Robert Droghini; Ramakrishnan Chidambaram; Xinhua Qian; Kenneth J. Natalie; Shawn K. Pack; Nathan Reising; Erqing Tang; Michael G. Fakes; Qi Gao; Feng Qian; Blisse Vakkalagadda; Chiajen Lai; Shan-Ming Kuang


Tetrahedron | 2003

Use of N-trifluoroacetyl-protected amino acid chlorides in peptide coupling reactions with virtually complete preservation of stereochemistry

Paul A. Jass; Victor W. Rosso; Saibaba Racha; Nachimuthu Soundararajan; John J. Venit; Andrew Rusowicz; Shankar Swaminathan; Julia Livshitz; Edward J. Delaney


Synlett | 2001

Aminolysis of Esters or Lactones Promoted by NaHMDS - A General and Efficient Method for the Preparation of N-Aryl Amides

Jianji Wang; Miguel Rosingana; Robert P. Discordia; Nachimuthu Soundararajan; Richard Polniaszek


Tetrahedron Letters | 2007

Surprising selectivity in the transformation of dimethoxy azaindoles

Kirsten Gesenberg; Prashant P. Deshpande; Annie Pullockaran; Feng Xu; Dedong Wu; Qi Gao; Charles Pathirana; John Castoro; Nachimuthu Soundararajan; Andrew J. Staab


Archive | 2015

SALTS OF PRODRUGS OF PIPERAZINE AND SUBSTITUTED PIPERIDINE ANTIVIRAL AGENTS

Yasutsugu Ueda; Timothy P. Connolly; John F. Kadow; Nicholas A. Meanwell; Tao Wang; Chung-Pin H. Chen; Kap-Sun Yeung; Zhongxing Zhang; David K. Leahy; Shawn K. Pack; Nachimuthu Soundararajan; Pierre Sirard; Kathia Levesque; Dominique Thoraval


Archive | 1999

Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes

Jollie D. Godfrey; David R. Kronenthal; Mark D. Schwinden; Sushil K. Srivastava; Keith Ramig; John J. Venit; Paul A. Jass; Saibaba Racha; John L. Dillon; Nachimuthu Soundararajan; Gerald L. Powers; Atul S. Kotnis

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