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Featured researches published by Naga Va Kommuri.


Journal of the American College of Cardiology | 2011

ASSOCIATION BETWEEN NOVEL BIOMARKERS AND ARTERIAL ELASTICITY INDEX AMONG HEALTHY MULTI-ETHNIC U.S. POPULATION

Sidakpal S. Panaich; Naga Va Kommuri; Sandip Zalawadiya; Vikas Veeranna; Ashutosh Niraj; Gayathri Ravi; Sony Jacob; Luis Afonso

Methods: Multi-Ethnic study of Atherosclerosis (MESA) is a population based study (n=6,814) of White (38%), Black (28%), Chinese (22%) and Hispanic (12%) subjects, aged 45-84 yrs, free from clinical cardiovascular disease. We performed post-hoc analysis of the NHLBI limited access dataset of MESA subjects (n=6,002) using multivariate regression analyses to determine the association of biomarkers with LAE and SAE derived from radial artery diastolic pulse wave contour registration in all subjects in a supine position using tonometry. Results: C reactive protein, interleukin-6, fibrinogen and factor-8 were negatively associated with both LAE and SAE. Plasma activated protein, homocysteine and microalbuminuria were negatively associated with SAE only and intracellular adhesion molecule levels were associated negatively with LAE. Conclusion: Markers of inflammation are associated with both LAE and SAE, whereas, markers of endothelial dysfunction and hemostasis are more strongly associated with SAE. The differential association of these biomarkers with LAE and SAE may further help our understanding of the putative biological pathways mediating adverse cardiovascular outcomes. Table 1: Association of Novel biomarkers with Arterial Elasticity Index Small Arterial Elasticity Index Large Arterial Elasticity Index Biomarkers Beta-coefficient [95% CI] p-value Beta-coefficient [95% CI] p-value High-sensitivity C-reactive protein (mg/L) -0.015 [-0.023 to -0.007] <0.001 -0.029 [-0.041 to -0.017] <0.001 Interleukin-6 (pg/mL) -0.030 [-0.043 to -0.016] <0.001 -0.036 [-0.057 to -0.016] <0.001 Plasmin-Antiplasmin Complex (nM) -0.041 [-0.064 to -0.017] 0.001 -0.012 [-0.022 to -0.047] 0.483 Fibrinogen (mg/dL) -0.071 [-0.115 to -0.027] 0.002 -0.086 [-0.150 to -0.020] 0.008 D-dimer (mcg/mL) -0.001 [-0.011 to 0.009] 0.864 0.009 [-0.005 to 0.023] 0.215 Factor-8 (%) -0.029 [-0.050 to -0.008] 0.005 -0.030 [-0.060 to -0.001] 0.049 Homocysteine (micromol/L) -0.037 [-0.067 to -0.006] 0.017 -0.032 [-0.012 to 0.076] 0.155 *Microalbuminuria (mg/g of creatinine) -0.039 [-0.071 to -0.007] 0.015 -0.015 [-0.061 to 0.031] 0.530 ¶Intercellular adhesion molecule-1 (ng/ml) -0.033 [-0.083 to 0.016] 0.188 -0.144 [-0.216 to -0.072] <0.001


Journal of the American College of Cardiology | 2011

ASSOCIATION BETWEEN ANTHROPOMETRIC MEASURES AND NOVEL BIOMARKERS AMONG NON-DIABETIC HEALTHY MULTIETHNIC U.S. ADULTS

Naga Va Kommuri; Sidakpal S. Panaich; Sandip Zalawadiya; Vikas Veeranna; Ashutosh Niraj; Sony Jacob; Luis Afonso

Methods: Multi-Ethnic study of Atherosclerosis (MESA) is a population based study (n=6,814) of White (38%), Black (28%), Chinese (22%) and Hispanic (12%) subjects, aged 45-84 yrs, free from clinical cardiovascular disease. We performed a post-hoc analysis of the NHLBI limited access dataset of MESA subjects (N=5534) to assess the relationship between a host of novel biomarkers with measures of anthropometry using multivariate adjusted linear regression analyses.


The American Journal of Medicine | 2012

The impact of prior heart failure hospitalizations on long-term mortality differs by baseline risk of death

Naga Va Kommuri; Todd M. Koelling; Scott L. Hummel


American Journal of Therapeutics | 2011

Low referral pattern for implantable defibrillator therapy in a tertiary hospital: referral physician survey and Monte Carlo simulation.

Tamam Mohamad; Sony Jacob; Naga Va Kommuri; Shalini Modi; Rajeev Aravindhakshan; Randy Lieberman


Journal of the American College of Cardiology | 2010

DISCHARGE EDUCATION IMPROVES KNOWLEDGE AND OUTCOMES IN HEART FAILURE PATIENTS

Naga Va Kommuri; Arun Damodaran; Todd M. Koelling


Journal of the American College of Cardiology | 2015

SPONTANEOUS ECHO CONTRAST: RISK FACTOR IN DILATED CARDIOMYOPATHY

Naga Va Kommuri; Todd M. Koelling


Journal of the American College of Cardiology | 2011

ANTHROPOMETRIC MEASURES AND CORONARY ARTERY CALCIUM: ANALYSIS OF A HEALTHY LOW-RISK MULTI-ETHNIC POPULATION

Naga Va Kommuri; Sidakpal S. Panaich; Sandip Zalawadiya; Vikas Veeranna; Ashutosh Niraj; Maithili Shenoy; Sony Jacob; Luis Afonso


Journal of the American College of Cardiology | 2011

RELATIONSHIP BETWEEN URINE MICROALBUMIN AND RED CELL DISTRIBUTION WIDTH: AN ANALYSIS OF THE NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY 1999 TO 2006

Sidakpal S. Panaich; Naga Va Kommuri; Sandip Zalawadiya; Vikas Veeranna; Ashutosh Niraj; Sony Jacob; Luis Afonso


Journal of the American College of Cardiology | 2011

RED CELL DISTRIBUTION LEVELS ARE INVERSELY ASSOCIATED WITH CARDIOVASCULAR FITNESS IN FEMALES, BUT NOT IN MALES - AN ANALYSIS OF THE NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY 1999 – 2004

Sidakpal S. Panaich; Naga Va Kommuri; Sandip Zalawadiya; Vikas Veeranna; Ashutosh Niraj; Maithili Shenoy; Chetankumar Chauhan; Sony Jacob; Luis Afonso


Journal of the American College of Cardiology | 2011

COMPARATIVE ANALYSIS BETWEEN FRAMINGHAM RISK SCORE AND A NEW BIOMARKER-BASED RISK SCORE (HARM SCORE) FOR CORONARY HEART DISEASE MORTALITY RISK PREDICTION

Sandip Zalawadiya; Vikas Veeranna; Ashutosh Niraj; Sidakpal S. Panaich; Naga Va Kommuri; Sony Jacob; Luis Afonso

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Luis Afonso

Wayne State University

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