Nalin B. Das

A novel Cu(II)-Mg-system for allylation and reduction of carbonyl compounds

Allylation of a variety of carbonyl compounds with allylic halides could be induced by Cu(II)-Mg to give corresponding homoallylic alcohols with high chemoselectivity. Cu(II)-Mg/THF-H2O was found to be an efficient reduction system of aldehyde to alcohol.

Tin(II) chloride dihydrate reduction of β,γ -unsaturated nitro-alkenes

Abstract β,γ -Unsaturated nitro-alkenes have been converted into α,β -unsaturated ketones in good yield by tin(II) chloride dihydrate in tetrahedrofuran.

SnCl2-SiO2: A selective reagent for efficient regeneration of carbonyls from nitrogeneous derivatives

ABSTRACT Semicarbazones, Phenyl hydrazones, 2,4-DNP and Oxime derivatives are converted into corresponding carbonyl compounds, mostly in quantitative yield by stannous chloride–silica gel. This has general application to various nitrogeneous derivatives.

An Efficient Nucleophilic Cleavage of Oxiranes to 1,2-Azido Alcohols†

Regioselective ring opening of oxiranes has been induced by the SnCl 2 ·2H 2 O–Mg–THF/NaN 3 –H 2 O system to give the corresponding 1,2-azido alcohols in good yields.

Microwave-assisted transformation of α,β- and β,γ-unsaturated nitroalkenes into carbonyl compounds

Vinyl and allylic nitroalkenes have been converted into the corresponding carbonyl compounds in good yield using tin(II) chloride dihydrate under microwave irradiation.

A general approach for the microwave-assisted regeneration of carbonyl compounds from their nitrogenous derivatives

A variety of nitrogenous derivatives of carbonyl compounds are rapidly converted into the corresponding carbonyl compounds in good yields using stannous chloride – silica gel under microwave irradiation

Tin(II) chloride dihydrate–a mild reagent for the transformation of 6-nitro-Δ5-steroids to 5α-hydroxy-6-ketosteroids

Reaction of excess hydrated tin(II) chloride with 6-nitro-Δ5-steroids (1a–g) and (5) in tetrahydrofuran furnishes 5α-hydroxy-6-ketosteroids (2a–g) and (6) respectively, in good yields.

Efficient nucleophilic cleavage of oxiranes to chlorohydrins

SnCl 2 ·2H 2 O–Mg and THF–H 2 O is an efficient system for the conversion of oxiranes to chlorohydrins.

Reaction of nitro-alkenes with iodotrimethylsilane: a new method for the conversion of vinyl nitrosteroids to ketosteroids

Iodotrimethylsilane generated in situ from chlorotrimethylsilane and sodium iodide effects the reduction of nitro-alkenes (1a–e) and (5) at –5 to 0 °C to furnish the ketones (2a–e) and (6) respectively as the major products.