Naoki Takatsuka
University of Shizuoka
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Featured researches published by Naoki Takatsuka.
Regulatory Peptides | 1992
Noboru Yanaihara; Tohru Mochizuki; Naoki Takatsuka; Kazuaki Iguchi; Keigo Sato; Hiroyoshi Kakuyama; Min Li; Chizuko Yanaihara
23 galanin-related peptides were synthesized by solid phase technology or conventional solution method. The purity of the products was carefully assessed by routine analytical criteria. Using these synthetic peptides, we have investigated the effects of galanins and structurally modified galanin peptides on glucose-stimulated insulin release using the isolated perfused rat pancreas, gastrin and somatostatin release using the isolated perfused rat stomach, the neurally-evoked muscle contractions in guinea pig ileum and the C-fiber response in the isolated spinal cord of the new born rat. The results suggest that the galanin amino-terminal 1-15 sequence is crucial for its activity in the above four systems. With the goal of developing a specific antagonist of galanin, synthetic galanin (1-15) analogues [D-Thr6,D-Trp8,9]galanin(1-15)ol, and [D-Trp8,9]galanin(1-15)ol were found to be a potent antagonist for inhibitory effect of galanin on glucose-induced insulin release.
Biomedical Research-tokyo | 1990
Tao Zhang; Minoru Hoshino; Kazuaki Iguchi; Junji Ishikawa; Tohru Mochizuki; Naoki Takatsuka; Chizuko Yanaihara; Masami Yokota; George H. Greeley; Noboru Yanaihara
Biomedical Research-tokyo | 1992
T. Nagashima; Naoki Takatsuka; T. Mochizuki; Minoru Hoshino; Chizuko Yanaihara; George H. Greeley; N. Yanaihara
Annals of the New York Academy of Sciences | 2006
Noboru Yanaihara; Tohru Mochizuki; Takeya Satoh; Shinjiro Imai; Kazuyuki Sasaki; Hiroyoshi Kakuyama; Hiroaki Hosoe; Naoki Takatsuka; Kazuaki Iguchi; Wei-Quan Luo; Nobuo Kurokawa; Chizuko Yanaihara
Biomedical Research-tokyo | 1994
Tohru Mochizuki; Asami Habu; Hiroyoshi Kakuyama; Naoki Takatsuka; Hiroaki Hosoe; Shigeru Mihara; Kazuaki Iguchi; Noboru Yanaihara
Biomedical Research-tokyo | 1994
Asami Habu; Shigeru Mihara; Takahide Ohishi; T. Mochizuki; Naoki Takatsuka; Kazuaki Iguchi; Chizuko Yanaihara; Noboru Yanaihara
Regulatory Peptides | 1992
Noboru Yanaihara; T. Mochizuki; Naoki Takatsuka; Kazuaki Iguchi; Minoru Hoshino; Chizuko Yanaihara; George H. Greeley; A. Kuwahara; Masanori Otsuka
Regulatory Peptides | 1992
Tohru Mochizuki; Naoki Takatsuka; Keiichi Ohshima; Keigo Sato; Hiroyoshi Kakuyama; Noboru Yanaihara
Peptide chemistry : proceedings of the ... Symposium on Peptide Chemistry | 1996
Tohru Mochizuki; Keiji Yoshioka; Yasuhiro Iida; Kazuaki Iguchi; Naoki Takatsuka; Minoru Hoshino; Atsukazu Kuwahara; Noboru Yanaihara
Peptide chemistry : proceedings of the ... Symposium on Peptide Chemistry | 1996
Xinmin Yu; Fumiyasu Kajiyama; Hiroaki Hosoe; Naoki Takatsuka; Kazuaki Iguchi; Tohru Mochizuki; Minoru Hoshino; Noboru Yanaihara
