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Lab on a Chip | 2005

Microfluidic operations using deformable polymer membranes fabricated by single layer soft lithography

Narayan Sundararajan; Dongshin Kim; Andrew Berlin

We show that it is possible to use single layer soft lithography to create deformable polymer membranes within microfluidic chips for performing a variety of microfluidic operations. Single layer microfluidic chips were designed, fabricated, and characterized to demonstrate pumping, sorting, and mixing. Flow rates as high as 0.39 microl min(-1) were obtained by peristaltic pumping using pneumatically-actuated membrane devices. Sorting was attained via pneumatic actuation of membrane units placed alongside the branch channels. An active mixer was also demonstrated using single-layer deformable membrane units.


Nano Letters | 2005

Composite Organic−Inorganic Nanoparticles (COINs) with Chemically Encoded Optical Signatures

Xing Su; Jingwu Zhang; Lei Sun; Tae-Woong Koo; Selena Chan; Narayan Sundararajan; Mineo Yamakawa; Andrew Berlin


IEEE\/ASME Journal of Microelectromechanical Systems | 2004

Three-dimensional hydrodynamic focusing in polydimethylsiloxane (PDMS) microchannels

Narayan Sundararajan; Michael S. Pio; Luke P. Lee; Andrew Berlin


Archive | 2003

Methods to increase nucleotide signals by raman scattering

Xing Su; Andrew Berlin; Selena Chan; Steven Kirch; Tae-Woong Koo; Gabi Neubauer; Valluri Rao; Narayan Sundararajan; Mineo Yamakawa


Archive | 2002

Microfluidic devices with porous membranes for molecular sieving, metering, and separations

Selena Chan; Narayan Sundararajan; Andrew Berlin; Mineo Yamakawa


Archive | 2005

Modification of metal nanoparticles for improved analyte detection by surface enhanced raman spectroscopy (sers)

Jingwu Zhang; Narayan Sundararajan; Sarah M. Ngola; Handong Li


Archive | 2002

Cascaded hydrodynamic focusing in microfluidic channels

Horst W. Haussecker; Narayan Sundararajan


Analytical Chemistry | 2006

Ultrasensitive detection and characterization of posttranslational modifications using surface-enhanced Raman spectroscopy.

Narayan Sundararajan; Danqian Mao; Selena Chan; Tae-Woong Koo; Xing Su; Lei Sun; Jingwu Zhang; Kung-bin Sung; Mineo Yamakawa; Philip R. Gafken; Tim Randolph; Dale McLerran; Ziding Feng; and Andrew A. Berlin; Mark B. Roth


Journal of Raman Spectroscopy | 2008

Experimental and statistical analysis methods for peptide detection using surface‐enhanced Raman spectroscopy

Breeana L. Mitchell; Anil Patwardhan; Sarah M. Ngola; Selena Chan; Narayan Sundararajan


Archive | 2006

Deformable polymer membranes

Narayan Sundararajan

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