Naseer Alam

Acetylenic thiophene derivatives from Blumea obliqua

Abstract The phytochemical investigations of Blumea obliqua afforded 5′-methyl-[5-(4-acetoxy-1-butynyl)]-2,2′-bithiophene, 5′-methyl-[5-(4-hydroxy-1-butynyl)]-2,2′-bithiophene, 5′-acetoxymethyl-5-(3-butene-1-ynyl)-2,2′-bithiophene and 5′-methyl-[5-(3-hydroxy-4-isovaleroxy-1-butynyl)]-2,2′-bithiophene. The first three thiophenes are known compounds whereas the fourth is a new natural product. The structures of these compounds were elucidated by spectroscopic methods.

Phytochemical study of Salvia moorcroftiana.

Four known flavonoids were isolated from the aerial parts of Salvia moorcroftiana.

Two New C-Glycosylflavones From Silene Conoidea

Abstract The butanol-soluble part of the methanolic extract of Silene conoidea afforded two new flavone glycosides having C-C linkage between C-8 and C-1″: 8-C-(4″-O-α-L-rhamnopyranosyl)-β-D-glucopyranosyldiosmetin (1) and 8-C-(4″-O-α-L-rhamnopyranosyl)-β-D-glucopyranosylapigenin (2). Both the glycosides were purified by HPLC and characterized spectroscopically. In addition to 1–2, α-spinasterol (3) and its giucoside (4) have also been reported for the first time from the investigated source.

Three New Diterpenoids from Euphorbia cheiradenia

Three new diterpene esters, cheiradone (1), cheiradone A (2), and cheiradone B (3), were isolated from the aerial parts of Euphorbia cheiradenia, collected in Iran. The structures were determined using different spectroscopic methods, including 1D and 2D NMR and X-ray diffraction analysis.

Acetylenic thiophenes from blumea obliqua

Abstract The acetylenic thiophene constituents from the aerial parts of Blumea obliqua yielded a novel dithienyl acetylene, 5′-Methylene-bis- 5 , 3 , 1 -2,2′-bithiophene, along with 5′-Hydroxymethyl5-(3-butene-1-ynyl)-2,2′-bithiophene and 5′-Carboxaldehyde-5-(3-butene-1-ynyl)-2,2′-bithiophene.

A new triterpenoidal saponin from the bark of Guaiacum officinale L

A new triterpenoidal saponin, akebonic acid-3-O-[α-L-rhamnopyranosyl-(1→3)-β-D-glucopyranosyl-( l→3)-α-L-rhamnopyranosyl-(l→2)-β-L-arabinopyranoside], named as guaianin Q (1), was isolated from the n-butanolic extract of the bark of Guaiacum officinale L. The structure of 1 was established with the help of the comparative studies of ID and 2D 1H - 13C NMR methods, FABMS, alkaline and acid hydrolyses. In addition to 1, a number of known saponins were also isolated and reported from the same source.

ISOPERADIONE : A NEW TRITERPENOID FROM SALVIA BUCHARICA

A new isomer of peradione (2) named as isoperadione (1) has been isolated along with peradione (2) and perovskone (3) from the hexane soluble part of Salvia bucharica. The structures of 1 - 3 were elucidated with the aid of modern spectroscopic techniques.