Navid Khalighinejad

Evaluation of microgap size and microbial leakage in the connection area of 4 abutments with Straumann (ITI) implant.

A microgap between implant and abutment can lead to mechanical and biological problems such as abutment screw fracture and peri-implantitis. The aim of this study was to evaluate microgap size and microbial leakage in the connection area of 4 different abutments to ITI implants. In this experimental study, 36 abutments in 4 groups (including Cast On, Castable, Solid, and Synocta abutments) connected to Straumann fixtures (with their inner part inoculated with bacterial suspension) and microbial leakage were assessed at different times. The size of the microgap in 4 randomized locations was then measured by scanning electron microscope. The data were analyzed by SPSS software and by 1-way variance statistical test, Kruskal-Wallis, and their supplementary tests (Mann-Whitney HSD and Tukeys; α = .05) at the next step. The effect of using different types of abutments was significant on the mean microgap size (P < .001) and on the mean number of leaked colonies (CFU/mL) through the connection area of the implant and abutment within the first 5 hours of the experiment (P = .012); however, it did not significantly influence microleakage at 24 hours, 48 hours, and 14 days (P = .145). Using Synocta abutments compared with Solid abutments will not provide us with more accommodation, and vice versa. Using Solid and Synocta abutments can significantly decrease the microgap size; however, Cast On abutments do not show a significant difference in terms of microgap compared with Castable abutments. Microleakage in the connection area is comparable for these 4 abutments.

Fracture resistance of structurally compromised and normal endodontically treated teeth restored with different post systems: An in vitro study

Background: With the aim of developing methods that could increase the fracture resistance of structurally compromised endodontically treated teeth, this study was conducted to compare the effect of three esthetic post systems on the fracture resistance and failure modes of structurally compromised and normal roots. Materials and Methods: Forty five extracted and endodontically treated maxillary central teeth were assigned to 5 experimental groups (n=9). In two groups, the post spaces were prepared with the corresponding drills of the post systems to be restored with double taper light posts (DT.Light-Post) (group DT.N) and zirconia posts (Cosmopost) (group Zr.N). In other 3 groups thin wall canals were simulated to be restored with Double taper Light posts (DT.W), double taper Light posts and Ribbond fibers (DT+R.W) and Zirconia posts (Zr.W). After access cavity restoration and thermocycling, compressive load was applied and the fracture strength values and failure modes were evaluated. Data were analyzed using two-way ANOVA, Tukey and Fisher exact tests (P<0.05). Results: The mean failure loads (N) were 678.56, 638.22, 732.44, 603.44 and 573.67 for groups DT.N, Zr.N, DT.W, DT+R.W and Zr.w respectively. Group DT+R.W exhibited significantly higher resistance to fracture compared to groups Zr.N, DT.W and Zr.w (P<0.05). A significant difference was detected between groups DT.N and Zr.W (P=0.027). Zirconia posts showed significantly higher root fracture compared to fiber posts (P=0.004). Conclusion: The structurally compromised teeth restored with double taper light posts and Ribbond fibers showed the most fracture resistance and their strengths were comparable to those of normal roots restored with double taper light posts. More desirable fracture patterns were observed in teeth restored with fiber posts.

Immunologic and psychologic parameters associated with geographic tongue

OBJECTIVE Several conditions have been associated with geographic tongue (GT). However, there is no consensus on the etiology of GT. The purpose of this study was to investigate whether immunologic and psychologic parameters are associated with diagnosis of GT. STUDY DESIGN A case-control study was performed on 170 participants (85 with GT, 85 controls). Unstimulated whole saliva was collected, and tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6) concentrations were measured. Anxiety level was measured using psychologic and physiologic testing instruments. An independent t test and a Pearson correlation analysis were performed with SPSS (α = .05). RESULTS There was a significant difference between the 2 groups regarding the salivary concentrations of TNF-α (P = .008) and IL-6 (P = .001). The concentration of salivary cortisol and state and trait anxiety levels in the GT group were significantly higher than those in the control group (P = .001). CONCLUSIONS Immunologic and psychologic parameters appear associated with GT and may constitute risk factors of this condition.

Evaluation of dental socket healing after using of porous titanium granules: Histologic and histomorphometric assessment in dogs

Background: Different methods have been suggested to preserve bone architecture following traumatic events such as teeth extraction. The purpose of the study was to histologically and histomorphometrically evaluate the dental socket healing after applying porous titanium granules (PTG) in dogs. Materials and Methods: Four healthy male dogs were involved in the present 6-weeks experimental animal study. Three sockets were surgically created in each side of dogs mandible. One of the sockets in one side was randomly filled by PTG and covered by a resorbable membrane (Tigran + membrane group). Another socket was left unfilled and just covered by the same membrane (membrane group) and the last one was left unfilled and uncovered as the control group. The dogs were killed at two time intervals (2 weeks and 6 weeks, two dogs at each time point). All samples were histologically evaluated under an optical microscope for a new bone formation. Data were analyzed by SPSS ver. 16 and Kruskal–Wallis and Mann–Whitney tests were used to compare data in different groups (α = 0.05). Results: There was a significant difference between the Tigran + membrane and the control group in 2 and 6 weeks in the mean amount of total regenerated bone (P < 0.05). The mean amounts of woven, lamellar, and total regenerated bone showed significant differences between 2 weeks and 6 weeks for all three groups (P < 0.05). Conclusions: It can be assumed that the use of Tigran bone substitute with membrane can promote the bone regeneration in bone defects.

The Effect of Three Different Disinfection Materials on Alginate Impression by Spray Method

Introduction. The aim of this study was to investigate the effect of three different types of disinfectant agents on alginate impression material after 5 and 10 minutes. Method and Materials. In this in vitro experimental study, 66 circular samples of alginate impression material were contaminated with Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans fungus. Except for control samples, all of them were disinfected with sodium hypochlorite 0.525, Deconex, and Epimax by way of spraying. Afterwards, they were kept in plastic bags with humid rolled cotton for 5 and 10 minutes. The number of colonies was counted after 24 and 48 hours for bacteria and after 72 hours for fungus. Statistical Mann-Whitney test was used for data analysis (α = 0.05). Results. After 5 minutes, Epimax showed the highest disinfection action on Staphylococcus aureus as it completely eradicated the bacteria. The disinfection capacity of different agents can be increased as time elapses except for Pseudomonas aeruginosa which was eradicated completely in both 5 and 10 minutes. Conclusion. This study revealed that alginate can be effectively disinfected by three types of disinfecting agents by spraying method, although Epimax showed the highest disinfection action after 10 minutes compared to other agents.

Effect of several bleaching agents on teeth stained with a resin‐based sealer

AIM To evaluate the effect of peroxide-based bleaching agents on teeth stained with AH26 sealer (Dentsply De Trey, Konstanz, Germany), using digital images and computer analysis. METHODOLOGY Thirty-five maxillary central incisors were root filled, and the internal walls of the access cavity were coated with AH26 sealer. Internal bleaching commenced 4 months after the root fillings. In three experimental groups (n = 10), the teeth were bleached for 21 days using 45% carbamide peroxide (CP) gel, 45% sodium perborate + carbamide peroxide (SP + CP) or sodium perborate + distilled water (SP + W). No bleaching was undertaken in the control group. Digital images of each specimen were made before treatment, 4 months after endodontic treatment and 2 weeks after bleaching. Colour differences (∆E) were calculated by determining L*a*b* values using digital images and imaging software. Differences between the original colour and sealer-stained teeth, between sealer-stained and bleached teeth and between original colour and bleached teeth were calculated. Data were analysed using one-way anova and Duncan tests (α = 0.05). RESULTS Colour differences between baseline and sealer staining were in the range of 8.1-9.9, but differences between the groups were not significant. After bleaching, the degree of lightening was essentially identical for the carbamide peroxide and sodium perborate + carbamide peroxide groups, but was significantly greater (P < 0.05) in these two groups than in the sodium perborate + water group. CONCLUSION For bleaching AH26 sealer-stained teeth, carbamide peroxide gel and carbamide peroxide gel mixed with sodium perborate were equally effective and significantly better than sodium perborate mixed with water.

The Effectiveness of GECB Pastille in Reducing Complications of Dry Socket Syndrome.

Background and Purpose. Dry socket syndrome is one of the most irritating complications after tooth extraction. This study aims to investigate the efficacy of pastille GECB compared to ZOE. Materials and Methods. 30 patients with dry socket syndrome were selected and divided into two groups. GECB pastille was produced with 3% Guaiacol, 3% Eugenol 1.6% Chlorobutanol, sized 3 × 7 × 10 mm. GECB was applied in one group, and ZOE was used for the other group. Duration of pain after treatment and painkiller intake values were recorded within 20 days. The data were analyzed with independent samples t-test, Mann-Whitney, and Chi-Square tests. Results. Pain persisted for 45.53 ± 33.34 minutes in patients treated with ZOE and 19.87 ± 21.80 minutes in those treated with GECB (P = 0.19). Patients in the ZOE group reported more painkiller intake within 20 days (P = 0.031). Conclusion. GECB showed more significant efficacy in reducing complications after tooth extraction.

Evaluation of Apical Microleakage in Open Apex Teeth Using MTA Apical Plug in Different Sessions

Aim. To compare microleakage of apexification using MTA in one or two sessions. Materials and Methods. 88 single rooted teeth were prepared and divided into two groups then received MTA apical plug. In the first group, the teeth were immersed in normal saline for 24 hours and then backfilled with guttapercha and AH26 sealer. In the second group, the teeth were obturated immediately after receiving apical plug. Four positive and four negative controls were selected. All specimens were placed in 1% methylene blue and decalcified in 5% nitric acid and finally were placed in methyl salicylate until getting transparent. All teeth were visualized for assessment of dye penetration under stereo dissecting microscope. Results. 36 and 35 teeth showed dye leakage in the first and second groups. Dye penetration into the entire canal length was confirmed in the positive control group, and in the negative control group no dye penetration was seen. Mean dye penetration in the first and second group was 5813 and 9152 μm. t-test revealed a significant difference between dye penetrations of two groups (P < 0.05). Conclusion. MTA requires adequate time for setting in the presence of the moisture, and final obturation should be delayed until final setting of MTA.

Effect of MTAD on the shear bond strength of self-etch adhesives to dentin.

Background: As the use of different irrigants to eliminate residual debris and smear layer in the field of endodontic is unavoidable, by considering the effect of irrigants on the bond strength of resin composite restorations, this study was designed to evaluate the effect of a mixture of a tetracycline isomer, an acid, and a detergent (MTAD) on the shear bond strength of two self-etch adhesives, Clearfil SE Bond and Adper Prompt L- Pop to dentin. Materials and Methods: The crowns of 80 extracted premolars were transversally sectioned to expose dentin. Flat dentin surfaces were wet abraded with 320-grit abrasive paper and randomly assigned to eight groups according to two self-etch adhesive and four dentin surface treatments: direct application over smear layer (no treatment), etching with 35% phosphoric acid for 15s, 1 min 5.25% NaOCl/1 min MTAD and 20min 1.3% NaOCl/5min MTAD. Shear bond strength was tested 24 h after storage in distilled water at 37°C in incubator. Data were analyzed using one-way ANOVA followed by duncan post-hoc (α=0.05). Results: Phosphoric acid etching prior to SE Bond application significantly decreased the shear bond strength to dentin (P<0.05). Application of MTAD clinical protocol (20min 1.3% NaOCl/5min MTAD) did not significantly decrease the shear bond strength of self-etch adhesives to dentin (P=0.745) Conclusions: Based on the results of present investigation, it seems that the use of clinical protocol of 1.3% NaOCl as a root canal irrigant and a 5-min application of MTAD as a final rinse to remove the smear layer has no adverse effect on the shear bond strength of self-etch adhesives to dentin.

Comparative Evaluation of Two Types of Immediately Loaded Implants Using Biomechanical and Histomorphometric Tests: An Animal Case Study

Introduction. In order to minimize the required time to regain esthetic and function, immediately loaded implants were suggested. The aim of this study was to comparatively evaluate the Nisastan and XIve implants using biomechanical and histomorphometric tests. Materials and Methods. In this experimental study, 6 Nisastan one-piece immediately loaded screw type implant (OPILS) and 6 Xive implants with 3.4 mm diameter and 11 mm long were used. The implants were immediately loaded with temporary coating. After three months, the torque required to break bone-implant contact was measured and was recorded. All implants were extracted with surrounding bone and histologically were evaluated. The data were inputted into the SPSS 11.5 to run student T-test statistical analyses (α = 0.05). Results. The success rates of both types of implants was 100%, and none of them failed due to mobility or bone loss. The mean removal torque value (RTV) was 142.08 and 40 N/Cm for Xive and Nisastan implants, respectively, and their RTVs showed a significant difference between two mentioned implants (P = 0.004). None of the histomorphometric values showed significant differences between the two implants (P > 0.05). Discussion. both systems have the capability to induce osseointegration under immediate loads but that Xive implants showed higher capability for bone contact.