Neelesh Sindhu
Lala Lajpat Rai University of Veterinary and Animal Sciences
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Publication
Featured researches published by Neelesh Sindhu.
Transboundary and Emerging Diseases | 2018
Sushila Maan; Aman Kumar; Akhil Kumar Gupta; Anita Dalal; Deepika Chaudhary; Tarun Kumar Gupta; Nitish Bansal; Vinjay Kumar; Kanisht Batra; Neelesh Sindhu; Ankit Kumar; Nand Kishore Mahajan; Narender S. Maan; Peter P. C. Mertens
Bluetongue (BT) and peste-des-petits-ruminants (PPR) are major transboundary diseases of small ruminant, which are endemic in India. Testing of bluetongue virus (BTV) and peste-des-petits-ruminants virus (PPRV) from recent outbreaks (2015-2016) in different regions of Haryana State of India revealed that 27.5% of the samples showed the presence of dual infection of BTV and PPRV. Analysis of Seg-2 of BTV (the serotype-determining protein) showed the presence of BTV-12w in several isolates. However, analysis of N gene fragment amplicons showed that viruses belong to lineage IV were most closely related to a pathogenic strain of PPRV from Delhi. This is the first report of co-circulation of PPRV lineage IV and bluetongue virus serotype 12 in the state.
Veterinary World | 2015
Tarun Kumar; Neelesh Sindhu; Gaurav Charaya; Ankit Kumar; Parmod Kumar; Gauri Chandratere; Divya Agnihotri; R. Khurana
Aim: Anaplasma marginale is a rickettsial pathogen responsible for progressive anemia in ruminants leading to huge economic losses. The objectives of this cross-sectional study were to determine the prevalence of anaplasmosis and therapeutic evaluation of traditional line of treatment. Materials and Methods: A total of 168 cattle presented to Teaching Veterinary Clinical Complex, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar during the period of 3 months (July-September, 2014) with history of fever, anorexia, reduced milk yield and tick infestation were analyzed for prevalence of hemoprotozoan diseases using classical giemsa stained thin blood smear parasitological method. Results: Out of these 168 animals, 7 (4.17%) were found to be suffering from anaplasmosis on the basis of presence of dense, rounded, intra-erythrocytic bodies situated on or near the margin of the erythrocytes. Overall prevalence of theileriosis and babesiosis were found to be 42.9% and 1.8%, respectively. Level of parasitemia was noticed to be 1.2%, 0.8% and 0.9% in babesiosis, theileriosis, and anaplasmosis, respectively. The most marked and common clinical signs reported in all the cases were severe anemia (hemoglobin=3-6 g/dl) and history of fever, followed by normal body temperature. Following treatment with oxytetracycline parenterally along with supportive therapy out of seven cases six got recovered without any side-effects. Conclusion: The current study indicates the emerging status of anaplasmosis in this part of the country as during the past few years there are very few reports showing the prevalence of clinical cases of anaplasmosis. Treatment with oxytetracycline yielded excellent result showing recovery in most of the clinical cases.
International Journal of Current Microbiology and Applied Sciences | 2017
Anita Dalal; Naresh Kumar Kakker; Aman Kumar; Deepika Chaudhary; Nitish Bansal; Neelesh Sindhu; Tarun Kumar; Narender S. Maan; Sushila Maan
Domestic as well as wild ruminants particularly sheep, white tailed deer and pronghorn health are severely affected by bluetongue disease. Bluetongue is an economically important disease that has an impact on international trade. The etiological agent, bluetongue virus (BTV) is the type species of the genus Orbivirus, family Reoviridae. BTV is non-enveloped with icosahedral symmetry encasing ten linear double-stranded RNA (dsRNA) genome segments (Seg-1 to Seg-10, with respect to size in decreasing order). The virion consists of three concentric protein shells viz. the outer capsid formed by VP2 and VP5, VP7 forms the core and VP3 forms subcore. The viral genome encodes 7 structural (VP1 to VP7) and 5 non-structural (NS1, NS2, NS3/ NS3a, NS4 and NS5 [S-10 ORF-2]) proteins (Pullenger et al., 2016, Maan et al., 2015, Maan et al., 2016). Apart from horizontal and vertical transmission, the virus is mainly transmitted biologically by Culicoides sp. biting midges (Maan et al., 2011; Mellor et al., 2000). Till date, a total of twenty-seven serotypes of BTV have been isolated and sequenced, although there are evidences of two additional putative serotypes (Maan et International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 12 (2017) pp. 2346-2348 Journal homepage: http://www.ijcmas.com
Veterinary World | 2015
Ankit Kumar; Neelesh Sindhu; Parmod Kumar; Tarun Kumar; Gaurav Charaya; Surbhi; V. K. Jain; Sridhar
Aim: The present study was undertaken to ascertain the incidence and clinical vital parameters in cases of primary ketosis in Murrah buffaloes brought to teaching veterinary clinical complex, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar and from adjoining villages of the district Hisar, Haryana, India. Materials and Methods: The investigation was conducted on 24 clinical cases (out of total 145 screened) of primary ketosis. The diagnosis was confirmed on the basis of clinical signs and significantly positive two tests for ketone bodies in urine (Rothera’s and Keto-Diastix strip test). Data collected were statistically analyzed using independent Student’s t-test. Results: Overall incidence of disease in these areas was found to be 16.55% and all the animals were recently parturited (mean: 1.42±0.14 month), on an average in their third lactation (mean: 2.38±0.30) and exhibited clinical signs such as selective anorexia (refusal to feed on concentrate diet), drastic reduction in milk yield (mean: 64.4±5.35%), ketotic odor from urine, breath, and milk and rapid loss of body condition. All the clinical vital parameters in ketotic buffaloes (body temperature, heart rate, respiration rate, and rumen movements) were within normal range. Conclusion: Primary ketosis in Murrah buffaloes was the most common seen in the third lactation, within the first 2 months after parturition with characteristics clinical signs and no variability in vital parameters. The disease has severe effect on the production status of affected animal.
Veterinary World | 2015
Parmod Kumar; Vishruth Jain; Ankit Kumar; Neelesh Sindhu; Tarun Kumar; Gaurav Charaya; Surbhi; Sandeep Kumar; Divya Agnihotri; Sridhar
Aim: The present study was undertaken to ascertain the clinical observation and haemato-biochemical studies on fever of unknown origin (FUO) in buffaloes which were presented for treatment at the Teaching Veterinary Clinical Complex (TVCC), Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS), Hisar. Materials and Methods: The investigation was conducted on total 106 clinical cases presented at “TVCC, LUVAS, Hisar.” Diseased animals having history of fever and increased rectal temperature were considered for the current study. Diagnosis of FUO was done on the basis of negative parasitological examination, culture examination, fecal and urine test. The cases in which etiology could not be established (such as pneumonia, metritis, traumatic reticuloperitonitis, urinary tract infection, trypanosomosis, diaphragmatic hernia, Brucellosis, and foreign body) were considered as true cases of FUO. Results: Out of 106 clinical cases different etiologies were identified in 76 (71.70%) cases including pneumonia, traumatic pericarditis, trypanosomosis, bacteremia, etc. and 30 cases (28.30%) remained undiagnosed even after detailed investigation. The mean rectal temperature (104.43±0.16°F), respiration rate (56.57±1.51/min) and pulse rate (83.40±1.77/min) of animals (n=30) suffering from FUO were significantly higher, whereas ruminal movement (1.00±0.23) was significantly lower compared to healthy control group. The mean value of hemoglobin, lymphocytes, and packed cell volume were significantly lower, whereas mean value of neutrophils was significantly higher compared to that of healthy control animals. Mean value of serum levels of glucose, phosphorus, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine phosphokinase (CPK), blood urea nitrogen (BUN), and creatinine were found to be significantly higher, whereas mean value of calcium value was significantly lower in all clinically affected animals compared to the healthy control group. Conclusion: About 28.30% cases of fever in buffaloes were found to be of unknown origin. Haemato-biochemical findings in cases of FUO in buffaloes revealed relative neutrophilia with lymphopenia, hyperglycemia, hypocalcemia, hyperphosphatemia, significantly increased AST, ALT, and CPK along with adversely altered kidney function indicators (elevated BUN and serum creatinine).
International Journal of Current Microbiology and Applied Sciences | 2018
Tarun Kumar; Manisha Punia; Divya Agnihotri; Neelesh Sindhu; Vishruth Jain
INTAS POLIVET | 2017
Suman; Vinod Kumar Jain; Dinesh Mittal; Neelesh Sindhu; Tarun Kumar
The Indian Journal of Veterinary Sciences and Biotechnology | 2016
Ankit Kumar; Parmod Kumar; Gaurav Charaya; Tarun Kumar; Neelesh Sindhu; Satbir Sharma
Journal of Animal Research | 2016
Suman; Vinod Kumar Jain; Neelesh Sindhu; Tarun Kumar; Ricky Jhambh; Manish Kumar; Parveen Goel
Buffalo Bulletin | 2016
D. K. Tiwari; Sandeep Saharan; Satbir Sharma; R. N. Choudhary; Neelesh Sindhu; Vikas Jaglan; Sandeep Potaliya
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Lala Lajpat Rai University of Veterinary and Animal Sciences
View shared research outputsLala Lajpat Rai University of Veterinary and Animal Sciences
View shared research outputsLala Lajpat Rai University of Veterinary and Animal Sciences
View shared research outputsLala Lajpat Rai University of Veterinary and Animal Sciences
View shared research outputsLala Lajpat Rai University of Veterinary and Animal Sciences
View shared research outputsLala Lajpat Rai University of Veterinary and Animal Sciences
View shared research outputsLala Lajpat Rai University of Veterinary and Animal Sciences
View shared research outputsLala Lajpat Rai University of Veterinary and Animal Sciences
View shared research outputsLala Lajpat Rai University of Veterinary and Animal Sciences
View shared research outputs