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Dive into the research topics where Neil S. Maxwell is active.

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Featured researches published by Neil S. Maxwell.


European Journal of Applied Physiology | 2000

Evaluation of the reliability and validity of a soccer-specific field test of repeated sprint ability

C. Wragg; Neil S. Maxwell; Jonathan H. Doust

Abstract The reliability and validity of a soccer-specific field test of repeated sprint ability was assessed. Seven male games players performed the repeated sprint test on six separate occasions. The temporal pattern of the mean sprint time was analysed by using coefficient of variation with confidence intervals (CI), and repeated measures ANOVA. A within subject mean coefficient of variation of 1.8% (95% CI, 1.5–2.4) was found for performance in the repeated sprint test across all six trials. The mean coefficient of variation across trials 2–4 was found to be 1.9% (95% CI, 1.3–3.1), compared to trials 4–6, where it was 1.4% (95% CI, 1.0–2.3). The ANOVA showed that a significant difference was present between the trials (F6,30 9.8, P < 0.001). A Tukey post-hoc test showed that significant differences were present between trial 1 and trials 3–6, and trial 2 and trial 5. The learning effect was complete by trial 3. Performance in the repeated sprint test was compared to total running time averaged from two repeats of the maximal anaerobic running test laboratory protocol. Mean sprint time in the repeated sprint test and total running time in the laboratory protocol had a correlation coefficient of r=−0.298 (P=0.516, n=7), suggesting that the energetics of the two tests are not closely related. In conclusion, this soccer-specific field test demonstrated high reliability.


Medicine and Science in Sports and Exercise | 2010

Precooling can prevent the reduction of self-paced exercise intensity in the heat

Rob Duffield; Robbie Green; Paul C. Castle; Neil S. Maxwell

PURPOSE This study investigated the effects of precooling on performance and pacing during self-paced endurance cycling in the heat and, further, the effects of cooling on contractile function as a mechanism for performance changes. METHODS After familiarization, eight male cyclists performed two randomized 40-min time trials on a cycle ergometer in 33 degrees C. Before the time trials, participants underwent either a 20-min lower-body cold-water immersion procedure or no cooling intervention. Before and after the intervention and the time trial, voluntary force (maximal voluntary contraction (MVC)), superimposed force (SIF), evoked twitch force (peak twitch force (Pf)), muscle temperature, and blood metabolites were measured. Further, measures of core and skin temperature and HR were recorded before, during, and after cooling and time trial. RESULTS Results indicated that cycling performance was improved with precooling (198 +/- 25 vs 178 +/- 26 W for precooling and control, respectively; P = 0.05). Although core, muscle, skin, and mean body temperatures were lower in the cooling condition until the 20th minute (P < 0.05), performance did not differ until the last 10 min of the time trial, by which time no differences in physiological measures were present. Further, while MVC and SIF were reduced postexercise in both conditions, MVC, SIF, and Pf were not different between conditions preexercise or postexercise. CONCLUSION In conclusion, a precooling intervention improved self-paced endurance exercise; however, the improvement in performance became evident after measured physiological differences induced by precooling had dissipated. Further, the lack of difference between conditions in MVC, SIF, or Pf indicates that improvements in performance did not result from an improvement in contractile function, suggesting that improvements may result from other mechanisms such as muscle recruitment.


Diabetes-metabolism Research and Reviews | 2011

Acute hypoxia and exercise improve insulin sensitivity (SI2*) in individuals with type 2 diabetes

Richard W.A. Mackenzie; Neil S. Maxwell; Paul C. Castle; Gary Brickley; Peter W. Watt

Hypoxia has been shown to increase glucose uptake in skeletal muscle using the contraction‐stimulated pathway, independent of the actions of insulin. Yet, the same stress has also been linked with causing insulin resistance and hyperglycaemia. The aim of this study was to examine the effects of acute hypoxia with and without exercise on insulin sensitivity (


Medicine and Science in Sports and Exercise | 1999

Intermittent running: muscle metabolism in the heat and effect of hypohydration

Neil S. Maxwell; Faith Gardner; Myra A. Nimmo

S{_{{\rm I}}}^{2*}


Journal of Sports Sciences | 2011

Heat acclimation improves intermittent sprinting in the heat but additional pre-cooling offers no further ergogenic effect

Paul C. Castle; Richard W.A. Mackenzie; Neil S. Maxwell; Anthony Webborn; Peter W. Watt

) in individuals with type 2 diabetes.


Journal of Thermal Biology | 2015

Isothermic and fixed intensity heat acclimation methods induce similar heat adaptation following short and long-term timescales

Oliver R. Gibson; Jessica Mee; James A. Tuttle; Lee Taylor; Peter W. Watt; Neil S. Maxwell

PURPOSE This study reports two studies that investigated the reason for a poorer intermittent supramaximal running performance previously found in the heat (Maxwell et al., The effect of climatic heat stress on intermittent supramaximal running performance in humans. Exp. Physiol. 81:833-845, 1996). The first study tested the hypothesis that it was due to different rates of substrate metabolism. The second study tested whether a greater level of hypohydration led to an earlier exhaustion time. METHODS A maximal anaerobic running test (MART) was the exercise model used. This involved repeated 20-s runs, each at increasing intensities, with 100 s of passive recovery between runs. RESULTS In study 1, eight male subjects performed the MART on two occasions at either 32.8+/-0.3 degrees C, 80.5+/-1.6% relative humidity (RH), or 21.3+/-0.4 degrees C, 48.8+/-2.2% RH. Needle biopsy samples were taken from the vastus lateralis muscle before and immediately after the MART. In study 2, 11 male subjects performed the MART in a moderately hypohydrated (HYPO) and euhydrated (EUH) state while in a cool environment. In study 1, performance was significantly worse in the hot compared with the cool environment (138+/-7 vs. 150+/-6 s, respectively, P<0.05). No differences were observed in the change in muscle glycogen (100.3+/-15.1 vs. 107.0+/-15.6 mmol glucosyl units x kg dry muscle(-1)) or muscle lactate (102.9+/-18.2 vs. 100.5+/-16.6 mmol x kg dry muscle(-1)) between the hot and cool environments, respectively. In study 2, performance was worse in the HYPO (148+/-9 s) compared with the EUH (154+/-9 s) trial (P<0.05). CONCLUSIONS These results indicate that a reduced intermittent supramaximal running performance in the heat is not caused by greater muscle glycogenolysis or lactate accumulation. Further, a poorer intermittent sprinting performance is experienced in a hypohydrated compared with a euhydrated state.


The Journal of Clinical Endocrinology and Metabolism | 2012

Intermittent exercise with and without hypoxia improves insulin sensitivity in individuals with Type 2 diabetes

Richard W.A. Mackenzie; Neil S. Maxwell; Paul C. Castle; Bradley T. Elliott; Gary Brickley; Peter W. Watt

Abstract The aim of this study was to determine the effect of 10 days of heat acclimation with and without pre-cooling on intermittent sprint exercise performance in the heat. Eight males completed three intermittent cycling sprint protocols before and after 10 days of heat acclimation. Before acclimation, one sprint protocol was conducted in control conditions (21.8 ± 2.2°C, 42.8 ± 6.7% relative humidity) and two sprint protocols in hot, humid conditions (33.3 ± 0.6°C, 52.2 ± 6.8% relative humidity) in a randomized order. One hot, humid condition was preceded by 20 min of thigh pre-cooling with ice packs (−16.2 ± 4.5°C). After heat acclimation, the two hot, humid sprint protocols were repeated. Before heat acclimation, peak power output declined in the heat (P < 0.05) but pre-cooling prevented this. Ten days of heat acclimation reduced resting rectal temperature from 37.8 ± 0.3°C to 37.4 ± 0.3°C (P < 0.01). When acclimated, peak power output increased by ∼2% (P < 0.05, main effect) and no reductions in individual sprint peak power output were observed. Additional pre-cooling offered no further ergogenic effect. Unacclimated athletes competing in the heat should pre-cool to prevent reductions in peak power output, but heat acclimate for an increased peak power output.


Journal of Thermal Biology | 2014

Reliability and validity of skin temperature measurement by telemetry thermistors and a thermal camera during exercise in the heat.

Carl A. James; Alan Richardson; Peter W. Watt; Neil S. Maxwell

Heat acclimation requires the interaction between hot environments and exercise to elicit thermoregulatory adaptations. Optimal synergism between these parameters is unknown. Common practise involves utilising a fixed workload model where exercise prescription is controlled and core temperature is uncontrolled, or an isothermic model where core temperature is controlled and work rate is manipulated to control core temperature. Following a baseline heat stress test; 24 males performed a between groups experimental design performing short term heat acclimation (STHA; five 90 min sessions) and long term heat acclimation (LTHA; STHA plus further five 90 min sessions) utilising either fixed intensity (50% VO2peak), continuous isothermic (target rectal temperature 38.5 °C for STHA and LTHA), or progressive isothermic heat acclimation (target rectal temperature 38.5 °C for STHA, and 39.0 °C for LTHA). Identical heat stress tests followed STHA and LTHA to determine the magnitude of adaptation. All methods induced equal adaptation from baseline however isothermic methods induced adaptation and reduced exercise durations (STHA = -66% and LTHA = -72%) and mean session intensity (STHA = -13% VO2peak and LTHA = -9% VO2peak) in comparison to fixed (p < 0.05). STHA decreased exercising heart rate (-10 b min(-1)), core (-0.2 °C) and skin temperature (-0.51 °C), with sweat losses increasing (+0.36 Lh(-1)) (p<0.05). No difference between heat acclimation methods, and no further benefit of LTHA was observed (p > 0.05). Only thermal sensation improved from baseline to STHA (-0.2), and then between STHA and LTHA (-0.5) (p<0.05). Both the continuous and progressive isothermic methods elicited exercise duration, mean session intensity, and mean T(rec) analogous to more efficient administration for maximising adaptation. Short term isothermic methods are therefore optimal for individuals aiming to achieve heat adaptation most economically, i.e. when integrating heat acclimation into a pre-competition taper. Fixed methods may be optimal for military and occupational applications due to lower exercise intensity and simplified administration.


Experimental Physiology | 1996

THE EFFECT OF CLIMATIC HEAT STRESS ON INTERMITTENT SUPRAMAXIMAL RUNNING PERFORMANCE IN HUMANS

Neil S. Maxwell; Tc Aitchison; Myra A. Nimmo

CONTEXT Hypoxia and muscle contraction stimulate glucose transport activity in vitro. Exercise and hypoxia have additive effects on insulin sensitivity in type 2 diabetics (T2D). OBJECTIVE The objective of the study was to examine the effectiveness of intermittent exercise with and without hypoxia on acute- and moderate-term glucose kinetics and insulin sensitivity in T2D. SETTING The study was conducted at a university research center. DESIGN, PARTICIPANTS, AND INTERVENTIONS Eight male T2D patients completed the following: 1) 60 min of continuous exercise at 90% lactate threshold in hypoxia (HyEx60); 2) intermittent exercise at 120% lactate threshold, separated by periods of passive recovery (5:5 min) in hypoxia [Hy5:5; O₂ ∼ 14.7 (0.2)%]; and 3) intermittent exercise (5:5 min) at 120% lactate threshold in normoxia (O₂ ∼ 20.93%). MAIN OUTCOME MEASURES Glucose appearance and glucose disappearance, using an adapted non-steady-state one-compartment model were measured. Homeostasis models of insulin resistance (HOMA(IR)), fasting insulin resistance index (FIRI), and β-cell function were calculated 24 and 48 h after exercise conditions. RESULTS Glucose disappearance increased from baseline (1.85 mg/kg · min⁻¹) compared with 24 h (2.01 min/kg · min⁻¹) after HyEx60 (P = 0.031). No difference was noted for both Hy5:5 (P = 0.064) and normoxia (P = 0.385). Hy5:5 demonstrated improvements in HOMA(IR) from baseline [d 1, 6.20 (0.40)] when comparisons were made with d 2 [4.83 (0.41)] (P = 0.0013). HOMA(IR) and FIRI improved in the 24 h (HOMA(IR), P = 0.002; FIRI, P = 0.003), remaining reduced 48 h after HyEx60 (HOMA(IR), P = 0.028; and FIRI, P = 0.034). CONCLUSION HyEx60 offered the greatest improvements in acute and moderate-term glucose control in T2D. Intermittent exercise stimulated glucose disposal and improved post-exercise insulin resistance, which was enhanced when exercise was combined with hypoxia (Hy5:5). The data suggest a use of hypoxic exercise in treatment of T2D.


Wilderness & Environmental Medicine | 2009

Hydration and the Physiological Responses to Acute Normobaric Hypoxia

Alan Richardson; Peter W. Watt; Neil S. Maxwell

New technologies afford convenient modalities for skin temperature (TSKIN) measurement, notably involving wireless telemetry and non-contact infrared thermometry. The purpose of this study was to investigate the validity and reliability of skin temperature measurements using a telemetry thermistor system (TT) and thermal camera (TC) during exercise in a hot environment. Each system was compared against a certified thermocouple, measuring the surface temperature of a metal block in a thermostatically controlled waterbath. Fourteen recreational athletes completed two incremental running tests, separated by one week. Skin temperatures were measured simultaneously with TT and TC compared against a hard-wired thermistor system (HW) throughout rest and exercise. Post hoc calibration based on waterbath results displayed good validity for TT (mean bias [MB]=-0.18 °C, typical error [TE]=0.18 °C) and reliability (MB=-0.05 °C, TE=0.31 °C) throughout rest and exercise. Poor validity (MB=-1.4 °C, TE=0.35 °C) and reliability (MB=-0.65 °C, TE=0.52 °C) was observed for TC, suggesting it may be best suited to controlled, static situations. These findings indicate TT systems provide a convenient, valid and reliable alternative to HW, useful for measurements in the field where traditional methods may be impractical.

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Paul C. Castle

University of Bedfordshire

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Mark Hayes

University of Brighton

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Lee Taylor

Loughborough University

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Jessica Mee

University of Brighton

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