Neil S. Sadick

Cosmeceutical Science in Clinical Practice

Cosmeceuticals – skin-care products that fall between a cosmetic and a pharmaceutical, with active ingredients that counter skin ageing and promote skin rejuvenation – are an invaluable adjunct to the cosmetic dermatologist or plastic surgeon performing minimally invasive aesthetic procedures. This guide from expert researchers and practitioners explains how best to integrate the potential of cosmeceutical products into the best international clinical practice.

Stimulation of hair growth in humans by cell-secreted proteins

VEGF, and Follistatin as measured by ELISA. The bioactivity of HSC is also assessed using a cell-based bioassay. Material from the same GMP manufactured lot of HSC was used in both the Phase I/II study as well as the physician’s sponsored IND study conducted by Dr. Ziering. The Phase I/II study consisted of male subjects with androgenetic alopecia receiving 8 x 0.1 cc intradermal injections of HSC or placebo into one of two regions on the scalp at baseline and 6 weeks. Baseline and 12 week Trichoscan images were obtained for subsequent analysis of hair growth efficacy. Dr. Ziering’s study enrolled 5 male and 4 female subjects, with each subject receiving a total of 20 x 0.1cc injections of HSC at baseline and a subsequent 20 injections at week 6.