Nicholas A. Nash
University of Louisville
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Publication
Featured researches published by Nicholas A. Nash.
Journal of Trauma-injury Infection and Critical Care | 2015
Matthew V. Benns; Michael E. Egger; Brian G. Harbrecht; Glen A. Franklin; Jason W. Smith; Keith R. Miller; Nicholas A. Nash; J. David Richardson
BACKGROUND Tube thoracostomy is a common procedure used in the management of thoracic trauma. Traditional teaching suggests that chest tubes should be directed in specific locations to improve function. Common examples include anterior and superior placement for pneumothorax, inferior and posterior placement for hemothorax, and avoidance of the pulmonary fissure. The purpose of this study was to examine the effect of specific chest tube position on subsequent chest tube function. METHODS A retrospective review of all patients undergoing tube thoracostomy for trauma from January 1, 2010, to September 30, 2012, was performed. Only patients undergoing computed tomography scans following chest tube insertion were included so that positioning could be accurately determined. Rib space insertion level and positioning of the tube relative to the lung parenchyma were recorded. The duration of chest tube drainage and the need for secondary interventions were determined and compared for tubes in different rib spaces and locations. For purposes of comparison, tubes placed above the sixth rib space were considered “high,” and those at or below it were considered “low.” RESULTS A total of 291 patients met criteria for inclusion. Forty-eight patients (16.5%) required secondary intervention. Neither high chest tube placement nor chest tube location relative to lung parenchyma was associated with an increased need for secondary interventions. On multivariate analysis, only chest Abbreviated Injury Scale (AIS) scores, mechanism, and volume of hemothorax were found to be significant risk factors for the need for secondary interventions. CONCLUSION Chest tube location does not influence the need for secondary interventions as long as the tube resides in the pleural space. The severity of chest injury is the most important factor influencing outcome in patients undergoing tube thoracostomy for trauma. Tube thoracostomy technique should focus on safe insertion within the pleural space and not on achieving a specific tube location. LEVEL OF EVIDENCE Therapeutic study, level IV.
Current Gastroenterology Reports | 2016
T. J. McKinney; Jayshil J. Patel; Matthew V. Benns; Nicholas A. Nash; Keith R. Miller
Vitamin D deficiency has recently been recognized as a widespread global disorder. Generally considered a direct extension of malnutrition, even subclinical hypovitaminosis D is now recognized in adequately nourished populations. Compared to the general population, the prevalence of hypovitaminosis D is greater in the critically ill population. In fact, several studies have shown poorer outcomes in critically ill patients discovered to be vitamin D deficient or insufficient. Controversy persists regarding vitamin D measurements, quantity of supplementation, and appropriate target level in various populations. Vitamin D has a vital role in calcium homeostasis and extra-skeletal health, such as immune function. Therefore, vitamin D supplementation may have a role for improving outcomes in critically ill patients. In this review, we will first discuss the metabolism and function of vitamin D under normal physiologic conditions. We will then explore the prevalence and prognostic value of vitamin D deficiency in critical illness. Finally, we will examine recent trials focusing on appropriate dosing, route of administration, and outcomes associated with vitamin D supplementation in the ICU.
Journal of The American College of Surgeons | 2016
Brian G. Harbrecht; Glen A. Franklin; Jason W. Smith; Matthew V. Benns; Keith R. Miller; Nicholas A. Nash; Matthew C. Bozeman; Royce Coleman; Daniel J. O'Brien; J. David Richardson
Injury Extra | 2010
Nicholas A. Nash; Jason Y.K. Chan; Keith R. Miller; Glen A. Franklin; Kadiyala V. Ravindra; Jason W. Smith
Journal of The American College of Surgeons | 2018
Lindsay F. Arnold; David S. Foley; Amirreza T. Motameni; Matthew C. Bozeman; Brian G. Harbrecht; Matthew V. Benns; Keith R. Miller; Nicholas A. Nash; Franklin A. Glen
Journal of The American College of Surgeons | 2018
Jessica Schucht; Neal Bhutiani; Brian P. Strollo; Keith R. Miller; Matthew V. Benns; Nicholas A. Nash; Glen A. Franklin; Jason W. Smith; Brian G. Harbrecht; Matthew C. Bozeman
Journal of The American College of Surgeons | 2018
Sarah Couch; William I. McKinley; Megan K. Mercer; Amirreza T. Motameni; Nicholas A. Nash; Brian G. Harbrecht; Matthew V. Benns; Keith R. Miller
American Surgeon | 2018
N Bhutiani; Keith R. Miller; Matthew V. Benns; Nicholas A. Nash; Glen A. Franklin; Jason W. Smith; Brian G. Harbrecht; Matthew C. Bozeman
Journal of The American College of Surgeons | 2017
Andrea K. Nagengast; Matthew V. Benns; Matthew C. Bozeman; Nicholas A. Nash; Jason W. Smith; Brian G. Harbrecht; Glen A. Franklin; Keith R. Miller
Journal of The American College of Surgeons | 2017
Keith R. Miller; Matthew V. Benns; Annie Nagengast; Matthew C. Bozeman; Nicholas A. Nash; Glen A. Franklin; Jason W. Smith; Brian G. Harbrecht
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University of Texas Health Science Center at San Antonio
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