Nicoletta Colombi
University of Turin
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Publication
Featured researches published by Nicoletta Colombi.
British Journal of Obstetrics and Gynaecology | 2015
Giuseppe Piccoli; Roberta Clari; Federica Neve Vigotti; Filomena Leone; Rossella Attini; G Cabiddu; Giuseppe Mauro; Natascia Castelluccia; Nicoletta Colombi; Irene Capizzi; A Pani; Tullia Todros; Paolo Avagnina
Although vegan–vegetarian diets are increasingly popular, no recent systematic reviews on vegan–vegetarian diets in pregnancy exist.
Health Information and Libraries Journal | 2011
Paolo Gardois; Roberto Calabrese; Nicoletta Colombi; Annamaria Deplano; Carla Lingua; Filomena Longo; Maria Cristina Villanacci; Roberto Miniero; Antonio Piga
BACKGROUND Considerable barriers still prevent paediatricians from successfully using information retrieval technology. OBJECTIVES To verify whether the assistance of biomedical librarians significantly improves the outcomes of searches performed by paediatricians in biomedical databases using real-life clinical scenarios. METHODS In a controlled trial at a paediatric teaching hospital, nine residents and interns were randomly allocated to an assisted search group and nine to a non-assisted (control) group. Each participant searched PubMed and other online sources, performing pre-determined tasks including the formulation of a clinical question, retrieval and selection of bibliographic records. In the assisted group, participants were supported by a librarian with ≥5 years of experience. The primary outcome was the success of search sessions, scored against a specific assessment tool. RESULTS The median score of the assisted group was 73.6 points interquartile range (IQR = 13.4) vs. 50.4 (IQR = 17.1) of the control group. The difference between median values in the results was 23.2 points (95% CI 4.8-33.2), in favour of the assisted group (P-value, Mann-Whitney U test: 0.013). CONCLUSIONS The study has found quantitative evidence of a significant difference in search performance between paediatric residents or interns assisted by a librarian and those searching the literature alone.
The Review of Diabetic Studies : RDS | 2013
Giorgina Barbara Piccoli; Roberta Clari; Sara Ghiotto; Natascia Castelluccia; Nicoletta Colombi; Giuseppe Mauro; Elisabetta Tavassoli; Carmela Melluzza; Gianfranca Cabiddu; Giuseppe Gernone; Elena Mongilardi; Martina Ferraresi; Alessandro Rolfo; Tullia Todros
BACKGROUND In the last decade, significant improvements have been achieved in maternal-fetal and diabetic care which make pregnancy possible in an increasing number of type 1 diabetic women with end-organ damage. Optimal counseling is important to make the advancements available to the relevant patients and to ensure the safety of mother and child. A systematic review will help to provide a survey of the available methods and to promote optimal counseling. OBJECTIVES To review the literature on diabetic nephropathy and pregnancy in type 1 diabetes. METHODS Medline, Embase, and the Cochrane Library were scanned in November 2012 (MESH, Emtree, and free terms on pregnancy and diabetic nephropathy). Studies were selected that report on pregnancy outcomes in type 1 diabetic patients with diabetic nephropathy in 1980-2012 (i.e. since the detection of microalbuminuria). Case reports with less than 5 cases and reports on kidney grafts were excluded. Paper selection and data extraction were performed in duplicate and matched for consistency. As the relevant reports were highly heterogeneous, we decided to perform a narrative review, with discussions oriented towards the period of publication. RESULTS Of the 1058 references considered, 34 fulfilled the selection criteria, and one was added from reference lists. The number of cases considered in the reports, which generally involved single-center studies, ranged from 5 to 311. The following issues were significant: (i) the evidence is scattered over many reports of differing format and involving small series (only 2 included over 100 patients), (ii) definitions are non-homogeneous, (iii) risks for pregnancy-related adverse events are increased (preterm delivery, caesarean section, perinatal death, and stillbirth) and do not substantially change over time, except for stillbirth (from over 10% to about 5%), (iv) the increase in risks with nephropathy progression needs confirmation in large homogeneous series, (v) the newly reported increase in malformations in diabetic nephropathy underlines the need for further studies. CONCLUSIONS The heterogeneous evidence from studies on diabetic nephropathy in pregnancy emphasizes the need for further perspective studies on this issue.
BMC Nephrology | 2016
Giorgina Barbara Piccoli; Irene Capizzi; Federica Neve Vigotti; Filomena Leone; Claudia D’Alessandro; Domenica Giuffrida; Marta Nazha; Simona Roggero; Nicoletta Colombi; Giuseppe Mauro; Natascia Castelluccia; Adamasco Cupisti; Paolo Avagnina
Dietary therapy represents an important tool in the management of chronic kidney disease (CKD), mainly through a balanced reduction of protein intake aimed at giving the remnant nephrons in damaged kidneys a “functional rest”. While dialysis, transplantation, and pharmacological therapies are usually seen as “high tech” medicine, non pharmacological interventions, including diets, are frequently considered lifestyle-complementary treatments. Diet is one of the oldest CKD treatments, and it is usually considered a part of “mainstream” management. In this narrative review we discuss how the lessons of complementary alternative medicines (CAMs) can be useful for the implementation and study of low-protein diets in CKD. While high tech medicine is mainly prescriptive, prescribing a “good” life-style change is usually not enough and comprehensive counselling is required; the empathic educational approach, on which CAMs are mainly, though not exclusively based, may support a successful personalized nutritional intervention.There is no gold-standard, low-protein diet for all CKD patients: from among a relatively vast choice, the best compliance is probably obtained by personalization. This approach interferes with the traditional RCT-based analyses which are grounded upon an assumption of equal preference of treatments (ideally blinded). Whole system approaches and narrative medicine, that are widely used in the study of CAMs, may offer ways to integrate EBM and personalised medicine in the search for innovative solutions respecting individualization, but gaining sound data, such as with partially-randomised patient preference trials.
BMC Nephrology | 2013
Martina Ferraresi; Roberta Clari; Irene Moro; Elena Banino; Enrico Boero; Alessandro Crosio; Romina Dayne; Lorenzo Rosset; Andrea Scarpa; Enrica Serra; Alessandra Surace; Alessio Testore; Nicoletta Colombi; Giorgina Barbara Piccoli
BackgroundComplementary and Alternative Medicines (CAMs) are increasingly practiced in the general population; it is estimated that over 30% of patients with chronic diseases use CAMs on a regular basis. CAMs are also used in hospital settings, suggesting a growing interest in individualized therapies. One potential field of interest is pain, frequently reported by dialysis patients, and seldom sufficiently relieved by mainstream therapies. Gentle-touch therapies and Reiki (an energy based touch therapy) are widely used in the western population as pain relievers.By integrating evidence based approaches and providing ethical discussion, this debate discusses the pros and cons of CAMs in the dialysis ward, and whether such approaches should be welcomed or banned.DiscussionIn spite of the wide use of CAMs in the general population, few studies deal with the pros and cons of an integration of mainstream medicine and CAMs in dialysis patients; one paper only regarded the use of Reiki and related practices. Widening the search to chronic pain, Reiki and related practices, 419 articles were found on Medline and 6 were selected (1 Cochrane review and 5 RCTs updating the Cochrane review). According to the EBM approach, Reiki allows a statistically significant but very low-grade pain reduction without specific side effects. Gentle-touch therapy and Reiki are thus good examples of approaches in which controversial efficacy has to be balanced against no known side effect, frequent free availability (volunteer non-profit associations) and easy integration with any other pharmacological or non pharmacological therapy. While a classical evidence-based approach, showing low-grade efficacy, is likely to lead to a negative attitude towards the use of Reiki in the dialysis ward, the ethical discussion, analyzing beneficium (efficacy) together with non maleficium (side effects), justice (cost, availability and integration with mainstream therapies) and autonomy (patients’ choice) is likely to lead to a permissive-positive attitude.SummaryThis paper debates the current evidence on Reiki and related techniques as pain-relievers in an ethical framework, and suggests that physicians may wish to consider efficacy but also side effects, contextualization (availability and costs) and patient’s requests, according also to the suggestions of the Society for Integrative Oncology (tolerate, control efficacy and side effects).
Journal of Nervous and Mental Disease | 2016
Francesco Oliva; Elisabetta Versino; Lorenzo Gammino; Nicoletta Colombi; Luca Ostacoli; Sara Carletto; Pier Maria Furlan; Rocco Luigi Picci
Abstract To estimate the relationship between type D personality and essential hypertension among patients visiting their GPs for any health problem, 101 hypertensive and 138 nonhypertensive patients were consecutively recruited and assessed using the Type D Personality Scale (DS14). The predictive value of type D personality was determined using a logistic regression model, taking into account the differences in recognized confounders between groups. Type D personality in the hypertension group was twice as frequent as in the no hypertension group and hypertension was more frequent among type D than non–type D patients. Logistic regression showed a significant predictive value of type D personality for hypertension, adjusting for sex, age, body mass index, family history of hypertension, living condition, education, and employment. Therefore, type D personality was strongly related to hypertension and it was a noteworthy predictor of hypertension in a real-world cohort of primary care patients.
International Journal of Artificial Organs | 2014
Giorgina Barbara Piccoli; Gabriella Guzzo; Federica Neve Vigotti; Stefania Scognamiglio; Valentina Consiglio; Emiliano Aroasio; Silvana Gonella; Natascia Castelluccia; Giuseppe Mauro; Nicoletta Colombi
Introduction and aims Renal function recovery (RFR), defined as the discontinuation of dialysis after 3 months of replacement therapy, is an uncommon occurrence. At a time when the “too early” start of dialysis is in discussion, a systematic review of the literature for cases in which patients recovered renal function after starting dialysis with chronic indications, including single cases and large series, may lead to attention being focused on this interesting issue. Methods The search strategy was built in Medline on Pubmed, in EMBASE and in the Cochrane Collaboration (August 2013) combining Mesh, Emtree and free terms: dialysis or hemodialysis, kidney function, renal function and recovery (publication date 2000-2013). The following tasks were performed in duplicate: titles and abstracts were manually screened, the data were extracted: title, author, objective, year, journal, period of study, multi-center, country, type of study. Results The systematic review retrieved 1 894 titles; 58 full papers were retrieved and the final selection included 24 papers: 11 case series or Registry data (4 from ANZdata) and 13 case reports. In spite of the high heterogeneity of the studies, overall they suggest that RFR occurs in about 1% of patients, without differences between PD and HD. RFR appears to be more frequent in elderly patients with renal vascular disease (up to 10% RFR in cholesterol emboli or scleroderma), but is reported in all types of primary and secondary kidney diseases. Conclusions RFR is a clinical event that should be looked for, particularly in elderly patients with vascular comorbidity.
Nephrology Dialysis Transplantation | 2016
Giorgina Barbara Piccoli; Fosca Minelli; Elisabetta Versino; Gianfranca Cabiddu; Rossella Attini; Federica Neve Vigotti; Alessandro Rolfo; Domenica Giuffrida; Nicoletta Colombi; Antonello Pani; Tullia Todros
Health Information and Libraries Journal | 2012
Paolo Gardois; Nicoletta Colombi; Gaetano Grillo; Maria Cristina Villanacci
Nephrology Dialysis Transplantation | 2013
Martina Ferraresi; Amina Pereno; Natascia Castelluccia; Roberta Clari; Irene Moro; Nicoletta Colombi; G Di Giorgio; Silvia Barbero; Giorgina Barbara Piccoli