Nilgün Şentürk

Clinical comparison of potassium-titanyl-phosphate (KTP) versus neodymium:YAG (Nd:YAG) laser treatment for lower extremity telangiectases

Abstract Background: The Nd:YAG laser has been considered the gold standard of treatment for leg veins, but pain and side effects have fueled physicians to use treatment alternatives. Objective: To compare the clinical efficacy of the long-pulsed 1064-nm Nd:YAG laser with KTP laser irradiation in the treatment of leg telangiectasia. Methods: A series of 16 patients with size-matched superficial telangiectases of the lower extremities were randomly assigned to receive three consecutive monthly treatments with the long-pulsed 1064-nm Nd:YAG on one leg and 532-nm KTP laser irradiation on the other. Results: For the 16 patients who completed the study, 64 leg vein sites were treated. Average clinical improvement scores were 1.94 and 1.25 for the KTP laser-treated leg and 3.38 and 3.50 for the Nd:YAG laser-treated leg with thin (≤ 1 mm) and large (1–3 mm) vessels, respectively. After the third treatment session, average improvement scores of 2.44, 1.31 and 3.75, 3.23 were given for the KTP and Nd:YAG laser-treated sides, respectively. Conclusion: Both the 1064-nm Nd:YAG and KTP lasers are effective in the treatment of lower extremity telangiectases. However, the KTP laser has very low efficacy with vessels larger than 1 mm and should not be elected when treating such vessels.

Serum galectin-3 levels in patients with Behçet's disease: association with disease activity over a long-term follow-up.

Background  There is a need for a laboratory marker that correlates with the clinical activity of Behçet’s disease (BD).

Narrow‐band ultraviolet B as a potential alternative treatment for resistant psychogenic excoriation: an open‐label study

Narrow‐band ultraviolet therapy has been used successfully for the treatment of inflammatory skin disorders and generalized pruritus. We have prospectively evaluated seven consecutive patients with resistant psychogenic excoriation (PE) treated with narrow‐band ultraviolet B (NB‐UVB). Approximately 70% of all patients showed improvement in their condition. NB‐UVB therapy was well tolerated, with no serious side effects. We may conclude that, when treating a patient with PE, NB‐UVB in combination with other approaches may provide extra benefit in resistant cases.

Goltz Syndrome (Focal Dermal Hypoplasıa) Wİth Exuberant Fat Herniations, Syndactyly, Papillomas, Skin Defects, Eye Involvement and False Positive Anti HIV Serology

Goltz Syndrome (Focal Dermal Hypoplasia) is a rare congenital mesoectodermal dysplasia with multisystemic involvement. It was first described by Goltz in 1962 and more than 200 cases reported worldwide.3 Skin lesions are characterized by athrophic, hyperpigmented linear or reticulated macules, multiple mucocutaneous papillomas, fat herniations or fat tumors. Besides the skin, other structures frequently involved are the skeletal system, eyes, teeth, hair, nails and central nervous system.1The association between Goltz syndrome and anti-HIV serology was not found in the literature. We report 32 year-old woman with typical cutaneous leisons of Goltz Syndrome associated with false positive anti-HIV serology and secondary infertility.

Dermatolojik Tedavide Kriyoterapi Kullanımı

Use of Cryotherapy in The Practice of Dermatology Cryosurgery, a technique utilizing heat-removed from tissues by application of cold, is effective in treating a wide array of skin conditions including many benign, premalignant, and malignant skin lesions. Because it also offers partial anesthesia, numerous lesions may be treated at one sitting. This efficient, effective, and economical method is now widely used by physicians who manage skin lesions Kriyocerrahi, dokunun dondurulmasina dayanan, bircok benign, premalign ve malign deri lezyonlarinm tedavisinde etkili sekilde kullanilan bir tekniktir. Kismen anestezi gerektirmesi, bircok lezyonun ayni anda tedavi edilebilirligi de tercih sebebidir. Etkili ve ekonomik bir metod olmasi ile bugun dermatologlar tarafindan yaygin olarak kullanilmaktadir.