Nils Mungan

Update on shaken baby syndrome: Ophthalmology

Purpose of review Shaken baby syndrome is a common problem with a high morbidity and mortality. Ophthalmologists help manage this condition and therefore must keep abreast of current advances. Recent findings Clinical updates include the discovery that retinal folds and traumatic retinoschisis can very rarely occur after crush head injury, but remain specific for shaken baby syndrome in other scenarios. Pathology updates include new studies on orbital histology and woodpecker anatomy that suggest the retinal and optic nerve hemorrhages in shaken baby syndrome are caused by shaking itself rather than secondary to intracranial pathology. Regarding this shaking injury, some primary prevention strategies have proven surprisingly effective. In the near future, serum biomarkers may be used as a screening tool for inflicted neurotrauma. Animal models such as the neonatal pig and computer models using finite element analysis are promising experimental techniques for studying shaken baby syndrome. Finally, child abuse recently became an accredited subspecialty of pediatrics, which will lead to further advances in patient care, education, research and prevention. Summary Ophthalmologists play a key role in the diagnosis of shaken baby syndrome. In addition, they are in a unique position to study ophthalmic aspects of the syndrome, which in turn furthers the overall understanding of this devastating condition.

Hypotension and bradycardia in infants after the use of topical brimonidine and beta-blockers

Brimonidine is a selective alpha-2 adrenergic agonist used to treat glaucoma. There have been several reports of central nervous system depression after its use in infants. We observed rapid-onset bradycardia and decreased blood pressure in addition to central nervous system depression in 2 infants who received concomitant topical brimonidine and beta-blockers.

Monovision for treatment of accommodative esotropia with a high AC/A ratio

PURPOSE The purpose of this study was to determine whether monovision will successfully reduce the near esodeviation in patients with high AC/A ratio accommodative esotropia. METHODS The records of all patients who wore monovision contact lenses for at least 3 months were retrospectively reviewed to determine baseline patient characteristics, long-term motor alignment, sensory status, and patient convenience. RESULTS TEN patients 10 to 28 years of age wore monovision contact lenses for a mean of 28.7 months to date. All patients maintained an esodeviation of < or = 10 prism diopters at distance and near, except 1 patient whose near esodeviation increased over time. Of the 5 patients for whom data were available, 1 experienced a significant decrease in stereoacuity. No patients discontinued monovision because of visual symptoms; however, 1 did so because of the inconvenience of contact lens care. No serious ocular side effects from contact lens wear were noted in the study. CONCLUSION Use of monovision contact lenses is a safe and effective method of reducing near-angle esodeviation associated with nonrefractive high AC/A ratio accommodative esotropia. Many patients are willing to accept the visual compromises inherent in monovision to eliminate wearing bifocal spectacles.

Combined use of cryotherapy and diode laser photocoagulation for the treatment of threshold retinopathy of prematurity.

PURPOSE Cryotherapy and indirect laser retinal photoablation are both effective in the treatment of retinopathy of prematurity (ROP). We describe the safety, efficiency, and effectiveness of combined cryotherapy and diode laser photocoagulation to treat threshold ROP. METHODS Records of patients developing threshold ROP from January 1, 1996 through December 31, 1998, were retrospectively reviewed to identify those treated with combined cryotherapy and photocoagulation and followed up for at least 45 days postoperatively. Diode laser was used to ablate posterior avascular retina, and cryotherapy was used for anterior retina. Data reviewed included ocular and systemic complication rates, treatment duration, number of laser burns, most recent fundus examination, visual acuity, and refraction. RESULTS In 13 patients, 23 eyes received combined treatment. No intraoperative complications occurred. Mean duration of anesthesia and treatment was 35 +/- 8 minutes/eye. A mean of 117 +/- 84 laser burns/eye were applied. In 20 of 23 eyes (87.0%), anatomic outcome was favorable at last examination. In 13 of 16 eyes (81.3%), functional (visual acuity) outcome was favorable (visual acuity better than 20/200) at 1 year. At 6 months or later, 14 of 16 eyes (87.5%) measured were myopic, of which 5 (31.3%) were highly myopic (> 6 diopters). CONCLUSIONS The effectiveness of treating ROP with combined cryotherapy and diode laser photocoagulation compares with that of either modality alone. By decreasing the number of laser applications, combined therapy may be faster and technically easier for eyes with very posterior ROP. This may decrease the number of complications seen when either excessive cryotherapy or laser retinal photoablation is used.

Spontaneous arteriovenous malformation of the orbit.

Editor,—Arteriovenous malformations (AVMs) and fistulas are rare in the orbit and generally have been associated with previous trauma. Of the 627 orbital tumours reported by Wright,1 only three were arteriovenous malformations. We report the clinical and pathological findings in a patient with an apparent spontaneous malformation. ### CASE REPORT A 74 year old white woman presented with a 2 month history of painless, progressive swelling of the right upper eyelid with no antecedent history of inflammation, trauma, or surgery. Ocular examination revealed visual acuity 20/30 in …