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Featured researches published by Nirmal Thampi John.


Indian Journal of Urology | 2013

Primary renal angiosarcoma

Sagar Sabharwal; Nirmal Thampi John; Ramani Manoj Kumar; Nitin S Kekre

Primary angiosarcoma of the kidney is a rare tumor with only a few case reports in the literature. Management is not standardized and the prognosis is poor. However, clinicians need to be aware of this uncommon entity.


Journal of clinical and diagnostic research : JCDR | 2015

A rare case of malignant fibrous histiocytoma/ pleomorphic undifferentiated sarcoma of the kidney.

Gregory Pathrose; Nirmal Thampi John; Ramani Manojkumar

Malignant Fibrous Histiocytoma (MFH) usually arises from the extremities with the retroperitoneum being the second most common site. We present the case report of a 58-year-old man presenting with fever and was detected to have a renal mass on evaluation. He underwent a radical nephrectomy with a preoperative diagnosis of renal cell carcinoma. But the final histopathological report was MFH. Primary renal MFH is extremely rare and is usually diagnosed on histopathology with the aid of immunohistochemistry.


Journal of clinical and diagnostic research : JCDR | 2014

Primary Renal Large Cell Neuroendocrine Carcinoma in a Young Man

Cornerstone Wann; Nirmal Thampi John; Ramani Manoj Kumar

Neuroendocrine tumours are usually located in the gastrointestinal or respiratory tract. A 23-year-old man was evaluated for loss of weight and a palpable left loin mass. CECT showed a large heterogeneously enhancing mass with calcification arising from the left kidney. He underwent an open radical nephrectomy. Histopathological examination revealed a large cell neuroendocrine carcinoma (LCNEC). LCNEC of the kidney is extremely rare and portends poor prognosis. It is usually a histopathological surprise and requires immunohistochemistry for confirmation.


Urology | 2015

Vesicourethral Fistula After Retrograde Primary Endoscopic Realignment in Posterior Urethral Injury

Rajat Arora; Nirmal Thampi John; Santosh Kumar

A 22-year-old male patient presented with iatrogenic vesicourethral fistula after immediate retrograde endoscopic realignment of urethra after a posterior urethral injury associated with pelvic fracture.


Journal of Stomatology, Oral and Maxillofacial Surgery | 2017

Cutaneous metastasis of renal cell carcinoma masquerading as an infected sebaceous cyst

Ranil Johann Boaz; Tanush Vig; Amit Jiwan Tirkey; Nirmal Thampi John; Ramani Manoj Kumar; Nitin S Kekre

Renal cell carcinoma (RCC) is the third most common genitourinary malignancy with an estimated one third of cases with metastatic disease at the time of diagnosis. Though rare, cutaneous metastasis from RCC is more frequent than any other genitourinary malignancy. Metastasis of RCC to skin carries poor prognosis as coexistent visceral spread is the norm. A 38-year-old man presented one year after radical nephrectomy for clear cell carcinoma of the left kidney with a submental lesion that proved to be metastatic. Clinical appearance of cutaneous RCC metastasis is varied and can closely mimic other skin lesions. It is incumbent on general practitioners, dermatologists and urologists to exercise diligence in clinical diagnosis of skin lesions in the background of previous oncological diagnosis.


Indian Journal of Urology | 2015

Squamous cell carcinoma of suprapubic cystostomy tract in a male with locally advanced primary urethral malignancy

Ranil Johann Boaz; Nirmal Thampi John; Nitin S Kekre

A 65-year-old man with stricture urethra underwent drainage of periurethral abscess and suprapubic cystostomy (SPC) placement. He presented to us 3 months later with a fungating ulcer at the site of perineal incision, the biopsy of which revealed squamous cell carcinoma (SCC). He underwent a total penile amputation, wide local excision scrotum, radical urethrocystoprostatectomy, ileal conduit with the en-bloc excision of the SPC tract. Histopathological examination of the suprapubic tract also revealed SCC. This is the first documented case of SCC of a suprapubic tract in the presence of primary urethral SCC.


International Braz J Urol | 2017

Does MRI help in the pre - operative evaluation of pelvic fracture urethral distraction defect? - a pilot study

Rajadoss Muthukrishna Pandian; Nirmal Thampi John; Anu Eapen; Belavendra Antonisamy; Antony Devasia; Nitin S Kekre


The Journal of Urology | 2018

PD59-04 A DOUBLE BLINDED, RANDOMIZED CONTROLLED TRIAL COMPARING TAMSULOSIN AND PLACEBO VERSUS TAMSULOSIN AND TADALAFIL IN MALE LOWER URINARY TRACT SYMPTOMS

Santhosh Nagasubramanian; Nirmal Thampi John; Belavendra Antonisamy; J Chandrasingh; Santosh Kumar; Antony Devasia; Nitin S Kekre


The Journal of Urology | 2018

MP18-09 GENOMIC PREDICTORS OF RESPONSE TO NEOADJUVANT CISPLATIN-BASED CHEMOTHERAPY IN UPPER TRACT UROTHELIAL CARCINOMA (UTUC)

Nirmal Thampi John; Amy Tin; Gopakumar Iyer; Renzo DiNatale; Nicole Benfante; Daniel D. Sjoberg; A. Ari Hakimi; Paul Russo; Jonathan A. Coleman


International Braz J Urol | 2017

Histopathological analysis of the non - tumour parenchyma following radical nephrectomy: can it predict renal functional outcome?

Rana Birendra; Nirmal Thampi John; Neelaveni Duhli; Antony Devasia; Nitin S Kekre; Ramani Manojkumar

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Nitin S Kekre

Christian Medical College

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Antony Devasia

Christian Medical College

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Santosh Kumar

Mahatma Gandhi Institute of Medical Sciences

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Anu Eapen

Christian Medical College

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Anuj Deep Dangi

Christian Medical College

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J Chandrasingh

Christian Medical College

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