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Dive into the research topics where Nirmala Paramanathan is active.

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Featured researches published by Nirmala Paramanathan.


Breast Cancer | 1998

Recent Progress with Breast-Conserving Volume Replacement Using Latissimus Dorsi Miniflaps in UK Patients

Richard Rainsbury; Nirmala Paramanathan

Significant volume loss during breast conserving surgery (BCS) can be anticipated in patients with small breast: tumor ratios, limiting the use of BCS in women with smaller breasts or larger tumors. Early experience with autogenous immediate volume replacement (IVR) at the time of BCS led to refinements in the technique, extending its role in clinical practice. The evolution of the technique has been examined, with particular reference to tumor selection, technique and modifications, histopathological findings, and cosmetic, radiological and psychological sequelae.Between 1991-1997, 62 patients underwent BCS and IVR using a latissimus dorsi (LD) miniflap. Tumors (diameter 22 [5-40] mm) were located in the upper outer quadrant (29) center (15) upper inner quadrant (17) and lower outer quadrant (1) of the breast. Operations lasted 129 (80-245) min, resecting specimens of 144 (37-345) g. Margins were positive in 8/62 specimens (13%) and local recurrence was recorded in 5/62 (8%), 4 of whom had not received radiotherapy. One local recurrence was treated by mastectomy (1.8% of whole group) and 4 were treated by re-excision and delayed radiotherapy. The cosmetic, radiological and psychological outcomes of the procedure compared favorably with BCS alone.Breast-conserving volume replacement with LD miniflaps extends the role of BCS without compromising resection, cosmesis or surveillance, and provides a further option in the surgical management of breast carcinoma.


Breast Journal | 2011

The impact of providing an oncoplastic service on the workload of a specialist breast unit.

Olubunmi Odofin; Kevin Harris; Nirmala Paramanathan; Siobhan Laws; Richard Rainsbury

Abstract:  Increasing breast specialization triggered a review of our surgical activity. All 10,000 elective inpatient and day case procedures between 1998 and 2008 were grouped into six categories: oncological, primary, secondary and revisional oncoplastic, and other breast and nonbreast procedures. Overall, surgical activity increased, with a rise in breast and a fall in nonbreast procedures, as a result of a changing caseload in each category (chi‐squared for linear trend = 55.24: p < 0.00001). These included increases in oncological procedures, secondary oncoplastic, and revisional oncoplastic procedures. Increased oncoplastic activity was associated with a reduction in other breast procedures (chi‐squared for linear trend = 04.94: p < 0.00001). The impact of breast specialization reported in the 1990′s has accelerated with the introduction of oncoplastic surgery. This has major short‐term and long‐term implications when planning a modern breast service.


American Journal of Surgery | 2008

Immediate latissimus dorsi miniflap volume replacement for partial mastectomy: use of intra-operative frozen sections to confirm negative margins.

Jennifer Rusby; Nirmala Paramanathan; Siobhan Laws; Richard Rainsbury


Plastic and reconstructive surgery. Global open | 2017

Patient-Reported Outcomes Are Better after Oncoplastic Breast Conservation than after Mastectomy and Autologous Reconstruction

Natalie Chand; Victoria Browne; Nirmala Paramanathan; Lashan Peiris; Siobhan Laws; Richard Rainsbury


Journal of Plastic Reconstructive and Aesthetic Surgery | 2017

Long-term effect of oncoplastic breast-conserving surgery using latissimus dorsi miniflaps on mammographic surveillance and the detection of local recurrence

S. Mele; D. Wright; Nirmala Paramanathan; Siobhan Laws; Lashan Peiris; Richard Rainsbury


Ejso | 2017

Is frozen section margin assessment during oncoplastic breast procedures worthwhile

Bashar Zeidan; Balvinder Shoker; Nirmala Paramanathan; Lashan Peiris; Siobhan Laws; Richard Rainsbury


Ejso | 2016

Patients are more satisfied after oncoplastic breast conservation than total autologous breast reconstruction

Natalie Chand; Nirmala Paramanathan; Lashan Peiris; Siobhan Laws; Richard Rainsbury


Ejso | 2016

Extreme oncoplastic surgery: Extending the boundaries of breast conservation

Roanne Fiddes; Nirmala Paramanathan; Natalie Chand; Siobhan Laws; Lashan Peiris; Richard Rainsbury


Ejso | 2016

Volume replacement or displacement? A mature study of patient-reported outcomes

Natalie Chand; Nirmala Paramanathan; Lashan Peiris; Siobhan Laws; Richard Rainsbury


Ejso | 2014

Cutting corners – Are we compromising oncological safety for aesthetic concerns: a review of a single institution's 21 year experience?

Siobhan Laws; Nirmala Paramanathan; Dick Rainsbury

Collaboration


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Siobhan Laws

Royal Hampshire County Hospital

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Richard Rainsbury

Royal Hampshire County Hospital

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Lashan Peiris

Royal Hampshire County Hospital

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Natalie Chand

Royal Hampshire County Hospital

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Dick Rainsbury

Royal Hampshire County Hospital

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Jennifer Rusby

The Royal Marsden NHS Foundation Trust

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Olubunmi Odofin

Royal Hampshire County Hospital

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Balvinder Shoker

Hampshire Hospitals NHS Foundation Trust

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Bashar Zeidan

Royal Hampshire County Hospital

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D. Wright

Royal Hampshire County Hospital

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