Noriyuki Yagi

1,6-Dihydro-3 (2H)-pyridinones as synthetic intermediates. Formal synthesis of (±)-tabersonine and (±)-catharanthine

Abstract Formal synthesis of (±)-tabersonine (3) and (±)-catharanthine (4) has been achieved starting from ethyl 1,6-dihydro-3 (2H)-pyridinone-1-carboxylate (1a) as a common synthon.

1,6-dihydro-3(2H)-pyridinones as synthetic intermediates. Total synthesis of (±)-tecomanine

Abstract The first and stereoselective total synthesis of (±)-tecomanine ( 1 ) has been achieved from ethyl 1,6-dihydro-3(2 H )-pyridinone-1-carboxylate ( 2 ) as a synthon.

1,6-dihydro-3(2H)-pyridinones as synthetic intermediates. A novel total synthesis of (±)-ibogamine and (±)-epiibogamine

A new synthesis of (±)-ibogamine (4) and (±)-epiibogamine (5), involving the intramolecular Michael addition of the keto unsaturated ester (11), is described.