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Dive into the research topics where O. T. G. Jones is active.

Publication


Featured researches published by O. T. G. Jones.


Journal of Immunological Methods | 1990

The use of diphenylene iodonium, an inhibitor of NADPH oxidase, to investigate the antimicrobial action of human monocyte derived macrophages.

A.K. Robertson; Andrew R. Cross; O. T. G. Jones; Peter W. Andrew

Diphenylene iodonium is an inhibitor of the respiratory burst-generating NADPH oxidase of phagocytes. The effect of this compound on human monocyte-derived macrophages and its usefulness in exploring the antimicrobial mechanisms of phagocytes was examined. 1 microM diphenylene iodonium inhibited hydrogen peroxide production by human macrophages and the activity of these cells against Toxoplasma gondii. At this concentration macrophage degranulation was unaffected.


Biochemical Journal | 1987

The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel

Lydia M. Henderson; J. B. Chappell; O. T. G. Jones


Biochemical Journal | 1988

Internal pH changes associated with the activity of NADPH oxidase of human neutrophils. Further evidence for the presence of an H+ conducting channel.

Lydia M. Henderson; J. B. Chappell; O. T. G. Jones


Biochemical Journal | 1969

The structural organization of haem synthesis in rat liver mitochondria

M. S. Jones; O. T. G. Jones


Biochemical Journal | 1988

The effect of the NADPH oxidase inhibitor diphenyleneiodonium on aerobic and anaerobic microbicidal activities of human neutrophils.

J. A. Ellis; S. J. Mayer; O. T. G. Jones


Biochemical Journal | 1988

Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge

Lydia M. Henderson; J. B. Chappell; O. T. G. Jones


Biochemical Journal | 1989

Superoxide generation is inhibited by phospholipase A2 inhibitors. Role for phospholipase A2 in the activation of the NADPH oxidase

Lydia M. Henderson; J. B. Chappell; O. T. G. Jones


Biochemical Journal | 1990

Electron-transport components of the 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine delta 12-desaturase (delta 12-desaturase) in microsomal preparations from developing safflower (Carthamus tinctorius L.) cotyledons.

M A Smith; Andrew R. Cross; O. T. G. Jones; W T Griffiths; Sten Stymne; K. Stobart


Biochemical Journal | 1970

Ferrochelatase of Rhodopseudomonas spheroides

M. S. Jones; O. T. G. Jones


Biochemical Journal | 1972

The utilization of iron and its complexes by mammalian mitochondria

Roger Barnes; J. L. Connelly; O. T. G. Jones

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