O Uddin
Northwestern University
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Publication
Featured researches published by O Uddin.
Journal of Neurosurgery | 2015
O Uddin; Raqeeb Haque; Patrick A. Sugrue; Yousef M. Ahmed; Tarek Y. El Ahmadieh; Joel M. Press; Tyler R. Koski; Richard G. Fessler
OBJECT Back pain is an increasing concern for the aging population. This study aims to evaluate if minimally invasive surgery presents cost-minimization benefits compared with open surgery in treating adult degenerative scoliosis. METHODS Seventy-one patients with adult degenerative scoliosis received 2-stage, multilevel surgical correction through either a minimally invasive spine surgery (MIS) approach with posterior instrumentation (n = 38) or an open midline (Open) approach (n = 33). Costs were derived from hospital and rehabilitation charges. Length of stay, blood loss, and radiographic outcomes were obtained from electronic medical records. Functional outcomes were measured with Oswestry Disability Index (ODI) and visual analog scale (VAS) surveys. RESULTS Patients in both cohorts were similar in age (Age(MIS) = 65.68 yrs, Age(Open) = 63.58 yrs, p = 0.28). The mean follow-up was 18.16 months and 21.82 months for the MIS and Open cohorts, respectively (p = 0.34). MIS and Open cohorts had an average of 4.37 and 7.61 levels of fusion, respectively (p < 0.01). Total inpatient charges were lower for the MIS cohort (
Seminars in Interventional Radiology | 2017
Andrew C. Gordon; O Uddin; Ahsun Riaz; Riad Salem; Robert J. Lewandowski
269,807 vs
Case Reports in Medicine | 2013
Raqeeb Haque; Sohaib Z. Hashmi; Yousef M. Ahmed; O Uddin; Alfred T. Ogden; Richard G. Fessler
391,889, p < 0.01), and outpatient rehabilitation charges were similar (
Journal of Spinal Disorders & Techniques | 2014
Raqeeb Haque; O Uddin; Yousef M. Ahmed; Tarek Y. El Ahmadieh; Sohaib Z. Hashmi; Amir Shah; Richard G. Fessler
41,072 vs
Journal of Vascular and Interventional Radiology | 2017
Nadine Abouchaleh; Karen Marshall; Ahmed Gabr; Ahsun Riaz; Rehan Ali; O Uddin; Joseph Ralph Kallini; Riad Salem; Robert J. Lewandowski
49,272, p = 0.48). MIS patients experienced reduced length of hospital stay (7.03 days vs 14.88 days, p < 0.01) and estimated blood loss (EBL) (EBL(MIS) = 470.26 ml, EBL(Open)= 2872.73 ml, p < 0.01). Baseline ODI scores were lower in the MIS cohort (40.03 vs 48.04, p = 0.03), and the cohorts experienced similar 1-year improvement (ΔODI(MIS) = -15.98, ΔODI(Open) = -21.96, p = 0.25). Baseline VAS scores were similar (VAS(MIS) = 6.56, VAS(Open)= 7.10, p = 0.32), but MIS patients experienced less reduction after 1 year (ΔVAS(MIS) = -3.36, ΔVAS(Open) = -4.73, p = 0.04). Preoperative sagittal vertical axis (SVA) were comparable (preoperative SVA(MIS) = 63.47 mm, preoperative SVA(Open) = 71.3 mm, p = 0.60), but MIS patients had larger postoperative SVA (postoperative SVA(MIS) = 51.17 mm, postoperative SVA(Open) = 28.17 mm, p = 0.03). CONCLUSIONS Minimally invasive surgery demonstrated reduced costs, blood loss, and hospital stays, whereas open surgery exhibited greater improvement in VAS scores, deformity correction, and sagittal balance. Additional studies with more patients and longer follow-up will determine if MIS provides cost-minimization opportunities for treatment of adult degenerative scoliosis.
CardioVascular and Interventional Radiology | 2018
Andrew C. Gordon; Ahmed Gabr; Ahsun Riaz; O Uddin; Nadine Abouchaleh; Rehan Ali; Joseph Ralph Kallini; Riad Salem; Robert J. Lewandowski
Intra-arterial therapies have high antitumor activity for both primary and secondary hepatic malignancies. Selective infusions allow increased delivery of cytoreductive therapy to the tumor bed while sparing the normal hepatic parenchyma. These therapies are now often applied in the outpatient setting or with short overnight hospital stays and have a growing role in the treatment of liver-dominant disease from metastatic colorectal cancer and from neuroendocrine tumors. Less commonly, intra-arterial therapies are applied to treat secondary hepatic malignancies from breast cancer, melanoma, pancreatic adenocarcinoma, and soft-tissue sarcomas. The available data are limited and generally retrospective observational cohort series of single institutions. The purpose of this article is to summarize the recent literature on outcomes for intra-arterial therapy in nonsurgical patients. Multi-institutional registries and prospective data are greatly needed, as intra-arterial therapies are increasingly applied in these patients to stop progression of chemorefractory tumors.
Journal of Vascular and Interventional Radiology | 2017
O Uddin; Robert J. Lewandowski; M Errea; Riad Salem; R.M. Hickey; Bartley Thornburg; J. Karp; Kush Desai
We describe an effective surgical technique in primary repair of the spinal dura during minimally invasive spine surgery (MISS). Objective. Minimally invasive spine surgery includes the treatment of intradural lesions, and proper closure of the dura is necessary. However, primary dural closure can be difficult due to the restricted space of MIS retractors and the availability of appropriate surgical instrumentation. Methods. We describe the use of a needle already used in the pediatric neurosurgical arena that can facilitate easier and safer closure of spinal dura through MISS retractors in two illustrative intradural cases. Results and Discussion. The primary dural closure technique is described and patient demographics are included. The instruments specifically used for the intradural closure through MIS retractor systems include (1) 4-0 Surgilon braided nylon (Covidien, Dublin, Ireland) with a CV-20 taper 1/2 circle, 10 mm diameter needle; (2) Scanlan (Saint Paul, MN, USA) dura closure set. Conclusion. Successful primary dural repair can be performed on primary and incidental durotomies during minimally invasive spinal surgery. We describe the novel use of a 10 mm diameter needle to help surgeons safely and efficiently close the dura with more ease than previously described.
Journal of Vascular and Interventional Radiology | 2017
Ahmed Gabr; Ahsun Riaz; Nadine Abouchaleh; Rehan Ali; O Uddin; Joseph Ralph Kallini; R.M. Hickey; Kush Desai; Bartley Thornburg; Robert J. Lewandowski; Riad Salem
Summary of Background Data:Traditional open surgical techniques for correction of adult degenerative scoliosis (ADS) are often associated with increased blood loss, postoperative pain, and complications. Minimally invasive (MIS) techniques have been utilized to address these issues; however, concerns regarding improving certain alignment parameters have been raised. Objective:A new “push-through” technique for MIS correction of ADS has been developed wherein a rod is bent before its placement into the screw heads and then contoured further to yield improved correction of radiographic parameters. Methods and Study Design:Preoperative and postoperative radiographic measurements of 3 patients who underwent MIS correction of scoliosis using the “push-through” technique were compared with 22 prior patients who had received traditional MIS correction. All patients received staged correction of scoliosis. The first stage involved insertion of lateral lumbar interbodies. Standing x-rays were then evaluated for overall global balance. The second stage involved appropriate MIS facetectomies, facet fusions, posterior transforaminal interbodies at lower lumbar segments, and finally the placement of rods. Technique Overview:(1) A long rod composed of titanium is bent with a mild lordosis and passed through the extensions of the screw heads cephalad to caudad. (2) The rod is passed fully through the incision so it extrudes from the caudal end of the construct. At this point, further lordosis is bent into the rods. (3) The rod is then pulled back into the appropriate position. (4) The unnecessary cephalad rod is then cut to appropriate length with a circular saw. (5) Rod reducers are then sequentially lowered and tightened to achieve the desired correction. Results:Mean age for all patients was 66.02 years. Preoperative coronal Cobb, sagittal vertical axis (SVA), and pelvic incidence (PI) were similar in all patients, whereas lumbar lordosis (LL) was smaller (15.27 vs. 29.85 degrees, P=0.00389) and pelvic tilt (PT) was larger (37.00 vs. 27.00 degrees, P=0.00011) in “push-through” patients. Postoperatively, “pushthrough” patients experienced greater correction of LL (21.93 vs. 3.70 degrees, P=0.00001), PI-LL (−18.57 vs. −0.26 degrees, P=0.00471), PT (−7.67 vs. −0.40 degrees, P=0.00341), SVA (−40.67 mm vs. 0.95 mm, P=0.05846), and coronal Cobb (−20.23 vs. −18.76 degrees, P=0.75). Conclusions:This new method of contouring a rod enables improved LL. This technique is easy to perform and can be a valuable tool in treating ADS using MIS techniques.
Journal of Vascular and Interventional Radiology | 2017
Ahmed Gabr; Joseph Ralph Kallini; Ahsun Riaz; Nadine Abouchaleh; Rehan Ali; O Uddin; Robert J. Lewandowski; Riad Salem
Journal of Vascular and Interventional Radiology | 2017
Ahmed Gabr; Ahsun Riaz; Nadine Abouchaleh; Rehan Ali; O Uddin; Joseph Ralph Kallini; Ryan Hickey; Kush Desai; Bartley Thornburg; Robert J. Lewandowski; Riad Salem