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Featured researches published by Oktay Alver.


Medical Science Monitor | 2017

A Clinical Scoring System for Diagnosis of Ocular Demodicosis

Oktay Alver; Sertaç Argun Kıvanç; Berna Akova Budak; Nazmiye Ülkü Tüzemen; Beyza Ener; Ahmet Tuncer Özmen

Background Demodex may cause chronic and refractory blepharitis with associated ocular surface problems, and its diagnosis and treatment can be quite challenging. In this study, our aim was to assess the efficacy of tea tree oil in Demodex treatment on caucasian patients in an industrialized region of Turkey, and to develop a systematic scoring system for extremely accurate diagnosis in the absence of advanced facilities. Material/Methods Charts of 412 patients with blepharitis were reviewed. A group of 39 out of 412 cases were identified as chronic and treatment-refractory, and therefore were enrolled in this study. Eyelashes from each of the lower and upper eyelids of both eyes were evaluated at ×40 and ×100 magnification using light microscopy. Treatment was started with 4% tea tree oil eyelid gel and 10% eyelash shampoo. Symptoms and findings were scored according to the most common complaints. Results The mean age of the patients was 54.1±15.4 years. Seventeen (43.5%) patients were male and 22 (56.5%) patients were female. In 30 out of the 39 patients (76.9%) D. folliculorum was detected. Symptoms disappeared in 25 patients. The mean score of patients who were Demodex-negative was 2.7±1.0, and the mean score of patients who were Demodex-positive was 3.8±1.6 (p=0.047). Ninety-four percent of those with a score of 4 and over were found to be Demodex-positive (p=0.025). Conclusions Treatment with tea tree oil can be successful. If there is no facility to identify Demodex under light microscopy, we recommend starting treatment for patients who have scores of 4 and over using the scoring chart developed in this study.


Acta parasitologica Turcica | 2015

[Evaluation of Two Methods (Nativ-Lugol Preparation and Enzyme-Linked Immunosorbent Assay) for Detection of Entamoeba histolytica in Stool Samples].

Oktay Alver; Tuncay Topac; Töre O

OBJECTIVE This study aims to compare the performance of Native-Lugol examination and EIA Antigen Detection Test using stool samples obtained from patients diagnosed as clinical gastroenteritis and submitted to the Parasitology Laboratory in Uludağ University between January 2010 and February 2011. METHODS The stool samples taken from 116 patients and sent to the laboratory of parasitology from various clinics including outpatient services have been investigated using Native-Lugol examination and EIA Antigen Detection Kit (Wampole® E. histolytica II Techlab®, Inc., Blacksburg, Virginia) methods on all the samples. RESULTS In one of 116 stool samples (%0,86), E. histolytica/E. dispar cysts and/or trophozoites were detected by using direct microscobic (nativ-lugol) method. E. histolytica specific antigen was detected in 34 (29.3%) out of the sample set, and the patients were given adequate treatment. The highest rate of E. histolytica specific antigen positivity were observed in 11-19 age group. CONCLUSION On account of the fact that the sensitivity of direct microscopy is quite low, it is concluded that, from the viewpoint of preventing the amebiasis suspected patients from false diagnosis and hence from receiving inadequate treatment, the use of the ELISA method is more appropriate and advantageous, as it is cost effective and does not require highly qualified staff.


Acta parasitologica Turcica | 2014

Investigation of serological results of patients with suspected toxoplasmosis admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008.

Oktay Alver; Guher Goral; İlker Ercan

OBJECTIVE The aim of this study is to investigate the distribution of anti-Toxoplasma gondii IgG and IgM antibodies in patients with suspected toxoplasmosis referred to the Uludağ University Medical School, Department of Medical Microbiology Enzyme-Linked Immunosorbent Assay (ELISA) laboratory over a 72-month period (March 2002-December 2008). METHODS The samples were analyzed using VIDAS (BioMérieux, France) IgG-avidity tests and the fluorescent enzyme-linked assay (ELFA) technique. RESULTS Results showed that the prevalence of anti-T. gondii IgG and IgM among women (29.2% and 2.02%, respectively) was higher than that of men (21.2% and 1.7%, respectively). The seroprevalence of anti-T. gondii IgG was 30.7% in childbearing-aged women, with rates ranging from 35.8% and 27.4% over the years. Avidity was found to be high, borderline, and lower (81.9%, 10.2%, and 7.9%, respectively) in the fertile age group of 166 women receiving the IgG avidity test. CONCLUSION Although the study data may not reflect our entire province, it virtually turns out that the risk of toxoplasmosis must be seriously taken into account, particularly when approaching some risk groups, such as seronegative women of fertile age, pregnant women, and immunocompromised patients.


Acta parasitologica Turcica | 2009

[The investigation of malaria cases in Bursa between 2006-2008].

Oktay Alver; E. Atıcı; O. Töre


Turkiye Klinikleri Tip Bilimleri Dergisi | 2010

Evaluation of virulence in various Candida species: in vitro and in vivo study.

Şaban Gürcan; Oktay Alver; İlker Ercan; Beyza Ener


Turkish Bulletin of Hygiene and Experimental Biology | 2018

The Epidemiology of Malaria in Bursa between 2013 and 2014

Oktay Alver; Beyza Ener


Investigative Ophthalmology & Visual Science | 2017

The role of Demodex folliculorum in chronic, treatment resistant blepharitis and clinical outcome

Berna Akova Budak; Sertaç Argun Kıvanç; Oktay Alver; Ahmet Ali Yucel; Beyza Ener; Ulku Tuzemen


Flora | 2017

Investigation of Parasitic Infection Rate in Stool Samples Submitted to Uludag University Parasitology Laboratory Between 2011-2015

Nazmiye Ülkü Tüzemen; Oktay Alver; Beyza Ener


Iranian Journal of Parasitology | 2016

Cerebral Malaria Treated with Artemisinin in the Intensive Care Unit: A Case Report.

Elif Ayşe Çizmeci; Nermin Kelebek Girgin; Ilkay Ceylan; Tekin Tuncel; Oktay Alver; Emin Halis Akalin


Acta parasitologica Turcica | 2014

[The epidemiology of malaria in Bursa--2009-2012].

Oktay Alver; Efrail Atici; Guher Goral

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