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Dive into the research topics where Oliver Nayler is active.

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Featured researches published by Oliver Nayler.


Brain Research Protocols | 1999

The in vivo minigene approach to analyze tissue-specific splicing.

Oliver Stoss; Peter Stoilov; Annette M. Hartmann; Oliver Nayler; Stefan Stamm

The exact mechanisms leading to alternative splice site selection are still poorly understood. However, recently cotransfection studies in eukaryotic cells were successfully used to decipher contributions of RNA elements (cis-factors), their interacting protein components (trans-factors) or the cell type to alternative pre-mRNA splicing. Splice factors often work in a concentration dependent manner, resulting in a gradual change of alternative splicing patterns of a minigene when the amount of a trans-acting protein is increased by cotransfections. Here, we give a detailed description of this technique that allows analysis of large gene fragments (up to 10-12 kb) under in vivo condition. Furthermore, we provide a summary of 44 genes currently investigated to demonstrate the general feasibility of this technique.


Nucleic Acids Research | 1998

SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements

Oliver Nayler; Wolf H. Strätling; Jean-Pierre Bourquin; Igor Stagljar; Lothar Lindemann; Heinrich Jasper; Annette M. Hartmann; Frank O. Fackelmayer; Axel Ullrich; Stefan Stamm


Molecular Biology of the Cell | 1999

THE INTERACTION AND COLOCALIZATION OF SAM68 WITH THE SPLICING-ASSOCIATED FACTOR YT521-B IN NUCLEAR DOTS IS REGULATED BY THE SRC FAMILY KINASE P59FYN

Annette M. Hartmann; Oliver Nayler; Franz Werner Schwaiger; Axel Obermeier; Stefan Stamm


Biochemical Journal | 1997

Characterization and comparison of four serine- and arginine-rich (SR) protein kinases

Oliver Nayler; Stefan Stamm; Axel Ullrich


Genomics | 1998

Human Transformer-2-beta Gene (SFRS10): Complete Nucleotide Sequence, Chromosomal Localization, and Generation of a Tissue-Specific Isoform ☆

Oliver Nayler; Claudia Čáp; Stefan Stamm


Journal of Biological Chemistry | 1998

The Cellular Localization of the Murine Serine/Arginine-rich Protein Kinase CLK2 Is Regulated by Serine 141 Autophosphorylation

Oliver Nayler; Frank Schnorrer; Stefan Stamm; Axel Ullrich


Journal of Cell Biology | 2000

The ER Repeat Protein Yt521-B Localizes to a Novel Subnuclear Compartment

Oliver Nayler; Annette M. Hartmann; Stefan Stamm


Archive | 2005

Novel PTP-20, PCP-2, BDP1, CLK, and SIRP proteins and related products and methods

Axel Ullrich; Naohito Aoki; Yeong Woong Kim; Hong Yang Wang; Zhengjun Chen; Oliver Nayler; Alexei Kharitonenkov


BioTechniques | 1999

ScienceLabDatabase: a computer program to organize a molecular biology laboratory.

Oliver Nayler; Stefan Stamm


Archive | 2001

Nucleic acids encoding CLK protein kinases

Axel Ullrich; Oliver Nayler

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Axel Ullrich

University of California

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Axel Ullrich

University of California

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