Olivia E. Atherton

Earlier adolescent substance use onset predicts stronger connectivity between reward and cognitive control brain networks

BACKGROUND Early adolescent onset of substance use is a robust predictor of future substance use disorders. We examined the relation between age of substance use initiation and resting state functional connectivity (RSFC) of the core reward processing (nucleus accumbens; NAcc) to cognitive control (prefrontal cortex; PFC) brain networks. METHOD Adolescents in a longitudinal study of Mexican-origin youth reported their substance use annually from ages 10 to 16 years. At age 16, 69 adolescents participated in a resting state functional magnetic resonance imaging scan. Seed-based correlational analyses were conducted using regions of interest in bilateral NAcc. RESULTS The earlier that adolescents initiated substance use, the stronger the connectivity between bilateral NAcc and right dorsolateral PFC, right dorsomedial PFC, right pre-supplementary motor area, right inferior parietal lobule, and left medial temporal gyrus. DISCUSSION The regions that demonstrated significant positive linear relationships between the number of adolescent years using substances and connectivity with NAcc are nodes in the right frontoparietal network, which is central to cognitive control. The coupling of reward and cognitive control networks may be a mechanism through which earlier onset of substance use is related to brain function over time, a trajectory that may be implicated in subsequent substance use disorders.

Personality Correlates of Risky Health Outcomes: Findings from a Large Internet Study.

Numerous studies have documented the effects of personality on health outcomes. However, which traits are most relevant to health, and the precise magnitude of their effects, is inconsistent across studies. The present study used a large sample (N=460,172) to replicate and extend the relations between the Big Five and three health-related outcomes: self-reported health, body mass index, and substance use. Low Conscientiousness predicted all outcomes, indicating that individuals who are less responsible and less self-controlled tend to report poorer health, be more overweight, and engage in more substance use. In addition, individuals who were more emotionally unstable (high Neuroticism) reported poorer health, and individuals prone to seek out social experiences and rewards (high Extraversion) engaged in more frequent substance use.

Bidirectional pathways between relational aggression and temperament from late childhood to adolescence

Relational aggression is linked to numerous adverse consequences. However, we know little about how temperament leads individuals to become perpetrators/victims of relational aggression, or how being a perpetrator/victim influences the development of temperament. We used longitudinal data from 674 Mexican-origin youth to examine relations between relational aggression and mother- and child-reported temperament from 5th grade (Mage=10.8; SD=0.60) through 11th grade (Mage=16.8; SD=0.50). Results show that: (a) high Negative Emotionality and low Effortful Control predicted increases in victimization; (b) low Effortful Control predicted increases in perpetration; (c) victims increased in Negative Emotionality and decreased in Effortful Control; and (d) perpetrators increased in Negative Emotionality and Surgency. Thus, temperament serves as both an antecedent to and a consequence of relational aggression.

Reciprocal relations between internalizing symptoms and frequency of alcohol use: Findings from a longitudinal study of Mexican-origin youth.

AIMS Alcohol consumption and internalizing symptoms, which often co-occur, pose considerable risk to the developing adolescent and have lasting public health consequences. Previous research has documented concurrent associations between alcohol use and symptoms of anxiety and depression, but the dearth of longitudinal research, particularly for ethnic minority youth, raises questions about the replicability and causal direction of these effects. The goal of the present research was to clarify these issues, and investigate whether different facets of anxiety and depression are uniquely associated with alcohol use in adolescence. METHOD The present research examined cross-lagged relations between frequency of alcohol use and internalizing symptoms, using data from a longitudinal study of 674 Mexican-origin youth (50% female) assessed at ages 14 and 16. RESULTS Alcohol use at age 14 prospectively predicted increases in overall internalizing symptoms, and overall internalizing symptoms at age 14 prospectively predicted increases in alcohol use. Reciprocal effects were consistently found for the general distress and anxious arousal facets, but not for anhedonic depression and a scale measuring the cognitive aspects of anxiety. CONCLUSIONS The findings provide evidence of reciprocal relations between alcohol use and internalizing symptoms, but also highlight the danger of treating all symptoms of anxiety and depression as interchangeable components of a single broad domain. Instead, symptoms common to both anxiety and depressive disorders (e.g., general distress) have the most robust reciprocal relations with alcohol use. Thus, intervention programs aimed at reducing early alcohol use by Mexican-origin youth should target this component of the internalizing domain.

The Co-development of Relational Aggression and Disruptive Behavior Symptoms From Late Childhood Through Adolescence

Researchers have debated whether relational aggression is a developmentally normative behavior or a sign of some underlying psychopathology. However, due to the dearth of longitudinal studies, we know little about how relational aggression and more severe forms of disruptive behavior co-develop. The present study examined bidirectional associations between relational aggression and two psychiatric disorders, oppositional defiant disorder (ODD) and conduct disorder (CD), using data from a longitudinal study of 674 Mexican-origin youth followed from age 10 to 16. Results showed that individuals who engaged in relational aggression tended to increase over time in ODD and CD symptoms, and conversely, individuals exhibiting symptoms of ODD and CD tended to increase in relational aggression. These findings held for boys and girls, for youth born in Mexico and the United States, and after controlling for physical aggression. Thus, relational aggression seems to be both a developmentally normative behavior and a predictor of future mental health problems.

Unsupervised self-care predicts conduct problems: the moderating roles of hostile aggression and gender

Despite widespread speculation about the detrimental effect of unsupervised self-care on adolescent outcomes, little is known about which children are particularly prone to problem behaviors when left at home without adult supervision. The present research used data from a longitudinal study of 674 Mexican-origin children residing in the United States to examine the prospective effect of unsupervised self-care on conduct problems, and the moderating roles of hostile aggression and gender. Results showed that unsupervised self-care was related to increases over time in conduct problems such as lying, stealing, and bullying. However, unsupervised self-care only led to conduct problems for boys and for children with an aggressive temperament. The main and interactive effects held for both mother-reported and observational-rated hostile aggression and after controlling for potential confounds.

The codevelopment of effortful control and school behavioral problems.

Effortful control refers to the propensity to regulate ones impulses and behaviors, to focus and shift attention easily, and to motivate the self toward a goal when there are competing desires. Although it seems likely that these capacities are relevant to successful functioning in the school context, there has been surprisingly little longitudinal research examining whether youth with poor effortful control are more likely to act out in the classroom, get suspended, and skip school. Conversely, there is even less research on whether youth who exhibit these school behavioral problems are more likely to decline over time in effortful control. We used multimethod data from a longitudinal study of Mexican-origin youth (N = 674), assessed biennially from 5th to 11th grade, to examine the codevelopment of effortful control and school behavioral problems. Bivariate latent growth curve models revealed a negative association between the trajectories of effortful control and school behavioral problems, indicating that steeper decreases in effortful control were related to steeper increases in school behavioral problems. Furthermore, this codevelopmental pattern was bidirectional; cross-lagged regression analyses showed that low effortful control was associated with relative increases in school behavioral problems, and school behavioral problems were associated with relative decreases in effortful control. Gender, nativity status, Mexican cultural values, and school-level antisocial behavior had concurrent associations with effortful control and school behavioral problems, but they did not moderate the codevelopmental pathways. We discuss the theoretical implications for personality development, as well as the practical implications for reducing school behavioral problems during adolescence. (PsycINFO Database Record

Developmental Precursors of Relational Aggression From Late Childhood Through Adolescence.

Relational aggression-a psychological form of aggression-has numerous negative consequences for physical and emotional health. However, little is known about the risk factors that lead youth to engage in relational aggression. Using multimethod data from a longitudinal research of 674 Mexican-origin youth, this study examined the influence of parents, siblings, and peers on the development of relational aggression. Increases in relational aggression from age 10 to 16 were associated with: (a) low levels of parental monitoring and (b) increased association with deviant peers and siblings. These results held across gender and nativity status. The findings suggest that multiple socialization agents contribute to the development of relational aggression. We discuss the practical implications for reducing relational aggression during adolescence.

The development of externalizing symptoms from late childhood through adolescence: A longitudinal study of Mexican-origin youth.

Youth who exhibit externalizing problems during childhood and adolescence are at an increased risk for a wide range of detrimental life outcomes. Despite the profound consequences of externalizing problems for children, their families, and their communities, we know less about the precise trajectory of externalizing symptoms across late childhood and adolescence, because of the paucity of fine-grained longitudinal research. The present study examined the development of externalizing symptoms in a large sample (N = 674) of Mexican-origin youth, assessed annually from age 10 to 17. Specifically, we conducted analyses to better understand the trajectories of attention-deficit-hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and conduct disorder (CD) symptoms (and their codevelopment), as well as how gender and cultural factors influence symptom trajectories. On average, ADHD symptoms slowly declined from age 10 to 17; ODD symptoms increased until age 13 and then declined thereafter; and, CD symptoms slowly increased until age 15 and then leveled off. ADHD, ODD, and CD symptoms predicted change in each other, indicating youth may accumulate multiple forms of externalizing problems over time. Boys reported fewer externalizing problems than girls, contrary to expectations. Consistent with the Immigrant Paradox, we found that 2nd + generation youth, youth who endorsed fewer traditional Mexican cultural values (traditional gender roles, traditional family values, and religiosity), and youth who engaged in less Spanish/more English language use were at increased risk for exhibiting ADHD, ODD, and CD symptoms from childhood through adolescence. We discuss the theoretical and practical implications of these developmental patterns among Mexican-origin youth.