Orville A. Beath

Effect of selenium on reproduction in rats.

Summary Low concentration (1.5 and 2.5 ppm) selenium in drinking water for two generations had no effect on the reproduction in rats. 2.5 ppm of Se reduced the number of young reared by the second generation of mothers. 7.5 ppm selenium prevented reproduction in females but fertility of the males was not affected.

Distribution of P32 in tissues of normal animals.

Summary The distribution and the specific activity of P32 in the various organs of normal animals was studied at 1, 2, and 12 hours after intraperitoneal administration of the isotope. The P32 was rapidly taken up by the serum and distributed in the various organs. It appears that the distribution of P32 was not directly related to the amount of phosphorus present in the tissue but depended on the permeability of the cells to the phosphate ion.