Osamu Asano

Synthetic studies on teleocidin I. Regioselective introduction of 4-amino and 7-acyl groups on indole derivative

Nitration of indole-3-carboxylic esters, 3 and 9, afforded 4-nitro derivatives, 4 and 10. 10 was regioselectively derived to 15, which contains substituents at 4- and 7-positions of indole nucleus similarly to teleocidins.

Total synthesis of bicyclomycin

Abstract Total synthesis of (±)bicyclomycin was achieved in 19 steps starting from diketopyperazine.

Synthetic studies on teleocidin. III: Regioselective introduction of nitro group at 4-position of substituted indole derivatives

Etude de la nitration des composes suivants: dihydro-5,6 dimethyl-6,6- et dihydro-5,6 isopropyl-7 pyrrolo [3,2,1-ij] quinoleinecarboxylates-1 de methyle, dimethyl 5a,8 hexahydro-4,5,5a,6,7,8 isopropyl-8 benzo [de] pyrrolo [3,2,1-ij] quinoleinecarboxylate-1 de methyle et dimethyl-6,9 isopropyl-6 tetrahydro-6,7,8,9 vinyl-9 benzo [g] indolecarboxylate-3 de methyle