Oscar Damia

Percutaneous lithotripsy in Valdivia-Galdakao decubitus position: our experience.

Percutaneous nephrolithotripsy (PNL) is actually the first therapeutic option to resolve complex renal stones. Our department initiated its experience in 1985 and treated the first 585 patients in ventral decubitus, as the original technique was described. Then, in 1998, the dorsal decubitus was adopted (Valdivia Uria), in which 695 patients were treated. Since 2006 the Valdivia Galdakao variant has been used. The Valdivia Galdakao position is an intermediate dorsal decubitus with extension of its homolateral lower limb and flexion of the contralateral. It is a practical way to place the patient for percutaneous renal surgery, avoiding hyperextensions and hyperflexions that can result in articular damage. It preserves cardiovascular and ventilatory dynamics and allows a better access to the respiratory tract. In this position, the bowel slips away from the puncture area lowering the risk of its damage. A single lumbar and genital sterile surgical field is created allowing antegrade and retrograde simultaneous endoscopic and even laparoscopic access, increasing efficiency and safety of the minimal invasive procedures. Between April 2006 and March 2008, 175 PNLs were performed in our department with the patient in Valdivia Galdakao position. The aim of this article is to describe our experience in this decubitus confirming that the Valdivia Galdakao is a safe, practical and versatile position that should be considered as first choice when a percutaneous renal surgery is indicated.

Histologic Changes After Urethroplasty Using Small Intestinal Submucosa Unseeded With Cells in Rabbits With Injured Urethra

OBJECTIVE To determine whether small intestine submucosa has the same regenerative capacity when urethroplasty is performed in injured urethras. METHODS Our experiment was conducted in 30 New Zealand male rabbits, all of which had urethral injury. One month after the injury, the animals were randomized into a control group or a group with onlay urethroplasty with small intestine submucosa. The animals were euthanized at 2, 4, 12, 24, and 36 weeks after urethroplasty, and their urethras were removed for histologic and immunohistochemical examination. Before the scheduled euthanasia, urethrography and cystoscopy were performed. RESULTS After 2 weeks, there was evidence of a continuous monolayer of stratified epithelial cells and absence of smooth muscle fibers. One month later, the epithelium showed no changes from the previously observed features, but some smooth muscle fibers (representing newly formed vessels) became apparent. After 3 months, the graft showed increased concentration of smooth muscle fibers. After 6 and 9 months, the density of smooth muscle cells remained unchanged. Fiber arrangement was irregular, particularly at the anastomosis site. Epithelial and smooth muscle phenotypes were confirmed by immunohistochemistry using anti-pan-citokeratin (AE1/AE3) antibodies and anti-α-smooth muscle actin, respectively. CONCLUSION Small intestine submucosa promotes regeneration in traumatized urethras, with slightly delayed epithelialization and abnormal distribution of smooth muscle. Urethral damage caused by trauma interferes with the normal healing process.

Estudio randomizado sobre continencia urinaria postprostatectomía radical con rehabilitación perineal kiesica previa

La incontinencia urinaria es una de las principales complicaciones luego de la realizacion de prostatectomia radical (PR). La rehabilitacion kinesica preoperatoria, podria ser de utilidad como tratamiento preventivo de esta complicacion. Demostrar la utilidad de la kinesiologia perineal preoperatoria en la recuperacion precoz de la continencia urinaria post prostatectomia radical. METODOS Ensayo Clinico Controlado Randomizado Aleatorizado. 38 pacientes fueron divididos en dos grupos de 19 previo a la realizacion de la PR. El primer grupo (K) recibio tratamiento kinesico preoperatorio, mientras que el segundo grupo (NK) no (grupo control). Se evaluo la continencia de orina a los 14, 30 y 60 dias post extraccion de sonda. RESULTADOS No hubo diferencias epidemiologicas y de biologia tumoral entre grupos. El porcentaje de pacientes continentes en el grupo K al los 14, 30 y 60 dias, respectivamente fue de 47,36%, 47,36% y 78,9%, respectivamente, mientras que en el grupo NK fueron de 47,36%, 47,36% y 89,4%, respectivamente (p>0,05). CONCLUSIONES Los ejercicios kinesicos perineales previos a la prostatectomia radical, no disminuyeron los tiempos de recuperacion de la continencia urinaria ni la ocurrencia de la misma.

Fractura de pene con lesión asociada de uretra: presentación de un caso y revisión de la literatura

Resumen es: Objetivo: La fractura de pene es una lesion que responde habitualmente a un traumatismo cerrado que ocurre con el pene en ereccion. Cerca del 20-30% de l...

Abordaje quirúrgico de la estenosis de anastomosis vesicouretral posprostatectomía radical

INTRODUCTION Vesicourethral anastomotic stricture following prostatectomy is uncommon but represents a challenge for reconstructive surgery and has a significant impact on quality of life. The aim of this study was to relate our experience in managing vesicourethral anastomotic strictures and present the treatment algorithm used in our institution. PATIENTS AND METHODS We performed a descriptive, retrospective study in which we assessed the medical records of 45 patients with a diagnosis of vesicourethral anastomotic stricture following radical prostatectomy. The patients were treated in the same healthcare centre between January 2002 and March 2015. Six patients were excluded for meeting the exclusion criteria. The stricture was assessed using cystoscopy and urethrocystography. The patients with patent urethral lumens were initially treated with minimally invasive procedures. Open surgery was indicated for the presence of urethral lumen obliteration or when faced with failure of endoscopic treatment. Urinary continence following the prostatectomy was determinant in selecting the surgical approach (abdominal or perineal). RESULTS Thirty-nine patients treated for vesicourethral anastomotic stricture were recorded. The mean age was 64.4 years, and the mean follow-up was 40.3 months. Thirty-three patients were initially treated endoscopically. Seventy-five percent progressed free of restenosis following 1 to 4 procedures. Twelve patients underwent open surgery, 6 initially due to obliterative stricture and 6 after endoscopic failure. All patients progressed favourable after a mean follow-up of 29.7 months. CONCLUSIONS Endoscopic surgery is the initial treatment option for patients with vesicourethral anastomotic strictures with patent urethral lumens. Open reanastomosis is warranted when faced with recalcitrant or initially obliterative strictures and provides good results.

VARIABLES PREOPERATORIAS PRONÓSTICAS EN EL CÁNCER DE RIÑÓN.

Resumen es: Objetivo: Analizar la correlacion existente entre factores preoperatorios en pacientes con cancer de rinon, y el hallazgo posterior de factores de mal pr...

V6-03 SYNCHRONOUS AND SIMULTANEOUS POSTERIOR REROPERITONEOSCOPIC BILATERAL ADRENALECTOMY.

INTRODUCTION AND OBJECTIVES: Retroperitoneal lymph node dissection (RPLND) is an important component of the management of testicular germ cell tumor (GCT) but its surgical morbidity is not insignificant. Herein we describe our updated experience with a midline extraperitoneal (EP) approach to RPLND for seminomatous and nonseminomatous GCT. METHODS: Between 2010 and 2015, from a prospectively collected IRB approved database, 122 consecutive patients underwent RPLND. Patients requiring aortic resection, retrocrural dissection or access to intraperitoneal disease were excluded. The remaining 69 patients underwent midline EP-RPLND. All post-chemotherapy (PC) cases underwent bilateral template dissection; all primary cases underwent extended ipsilateral templates. Perioperative and long-term outcomes were analyzed and a descriptive analysis using SAS was performed. RESULTS: 68 patients underwent midline EP-RPLND successfully (98.6%). Median age was 28 years (range1⁄417-55). Median follow up was 15.3 months (IQR: 5.7-24.3). On pre-operative imaging the size of retroperitoneal mass or lymphadenopathy was <2 cm in 29 patients, 2-5 cm in 15 patients, and >5 cm in 24 patients, of which 19 were >10cm. 3 patients underwent cavectomy. Median EBL was 325 mL (IQR: 200-612.5). Median number of lymph nodes (LN) resected was 36 (IQR: 24.5-49); median number of positive nodes was 1 (IQR: 04). Median return of bowel function was 2 days (1-3) and LOS was 3 days (2-4). There were no cases of ileus. 13 patients (19.1%) had complications within 90-days: 12 were Clavien grade 2 (17.6%), there was 1 grade 3b complication (1.5%). Antegrade ejaculation rates were 91.6% in the primary group and 96.8% in the PC group. CONCLUSIONS: Midline EP-RPLND can be performed safely without compromising completeness of resection. This approach is associated with a faster return of bowel function, lower rates of ileus and shorter LOS.

V1-12 ROBOTIC-ASSISTED RADICAL PROSTATECTOMY AND CONTINENT URINARY STOMA (MITROFANOFF) IN A 7 YEAR CHILD.

INTRODUCTION AND OBJECTIVES: Urethrectomy with appendicovesicostomy is a treatment option for low stage urethral cancer. We present a novel minimally-invasive surgical approach which allows for robotic appendicovesicostomy to be performed simultaneously with open urethrectomy. METHODS: A 71 year-old man presented with clinically-localized squamous cell carcinoma of the urethra. He underwent a traditional open urethrectomy with simultaneous robotic-assisted bladder neck closure, omental J flap interposition, and appendicovesicostomy. The robot was side-docked to allow for a perineal surgeon to work in tandem with the robotic surgeon. RESULTS: Total operating room time was 391 minutes. Robotic console time was 281 minutes. Length of stay was four days. There were no complications, and no secondary procedures were required. Final pathology demonstrated T2 squamous cell carcinoma with negative margins. At 6 months follow up, the patient is continent and cancer-free. CONCLUSIONS: Simultaneous extirpative surgery and minimally-invasive urinary tract reconstruction is possible for patients with urethral cancer. Side-docking the robot allows for two surgical teams to work concurrently. This approach may be applicable to other procedures requiring both open perineal and laparoscopic intraabdominal access.

V10-05 ROBOT ASSISTED BLADDER AUGMENTATION AND BILATERAL URETERAL REIMPLANTATION

INTRODUCTION AND OBJECTIVES: Despite use of barbed suture during robot-assisted radical prostatectomy or partial nephrectomy, concerns have been raised about a high early failure rate when used during minimally-invasive pyeloplasty (MIP). In this video, we present our technique of robotic pyeloplasty using barbed suture, review the literature on barbed suture for MIP and discuss the controversies, tips, and tricks. METHODS: We present a case of a 55 year old man with rightsided uretero-pelvic junction obstruction (UPJO). The patient was placed in the modified flank position. Port placement was a 12 mm camera port, two 8 mm robotic ports, and a 5 mm assistant port. The robot was docked at a 30-degree angle to the flank. A robotic cautery hook was used to aid with fine hemostatic dissection. The renal pelvis and upper ureter were mobilized to reveal a crossing vessel. Round tip scissors were used to perform dismemberment and spatulation (Anderson-Hynes technique). The ureter was transposed over the crossing vessel and anastomosis was performed using a unidirectional barbed suture (3-0 Stratafix ; Ethicon, Somerville, NJ, USA) in a running fashion. Following completion of the posterior layer, an antegrade ureteral stent was placed followed by closing the anterior layer in a similar fashion. RESULTS: Strategies for successful robotic pyeloplasty using barbed suture include: (1) selection of appropriate barbed suture e suture composition, absorbability, distribution of barbs and needle type vary between manufacturers (2) minimizing tension during suture placement to avoid tissue necrosis (3) use of round tip scissors to avoid spiral spatulation of the ureter (4) use of the obstructing UPJ tissue as a handle-hold for manipulation (5) avoid use of 12 mm assistant port for needle entry by utilizing needle placement via a robotic port. Advantages of barbed suture include no loss of tension as seen in non-barbed monofilament suture with possibility of suture loosening, and use of a “continuous interrupted” method; the barbs allow the anastomotic tension to be evenly spread to avoid gaps and mimic interrupted suture. Of 18 patients who have undergone laparoscopic or robotic pyeloplasty using barbed suture at our institution, the success rate was 17/ 18 (94%). CONCLUSIONS: Barbed suture for MIP provides a watertight anastomosis that is technically easier to perform. A key principle is to know your barbed suture as incorrect suture selection may compromise success. Our results demonstrate excellent success rates when using the barbed suture for MIP.

La incidencia de márgenes quirúrgicos positivos tras prostatectomía radical asistida por robot: ¿tiene la experiencia del cirujano influencia en todos los estadios patológicos?

OBJECTIVE The aim of this study is to analyze the clinical and surgical features of patients who underwent robotic-assisted radical prostatectomy (RARP) at our institution, and the impact of the surgeons experience in the oncological results related to pathological stage. MATERIAL AND METHODS An analysis of 300 RARP consecutively performed by the same urologist was conducted. Patients were divided into 3 groups of 100 patients in chronological order, according to surgery date. All patients had organ-confined clinical stage. Variables which could impact in positive margins rates were analyzed. Finally, positive surgical margins (PSM) in regard to pathological stage and surgeons experience were compared and analyzed. RESULTS No significant differences were found in variables which could impact in PSM rates. The overall PSM rate was 21%, with 28% in the first group, 20% in the second, and 16% in the third (P = .108). Significant lineal decreasing tendency was observed (P = .024). In pT2 patients, the overall PSM rate was 16.6%, with 27%, 13.8%, and 7.3% in each group respectively (P = .009). A significant difference was found between group 1 and group 3 (P = .004). In pT3 patients, the surgeons experience was not significantly associated with margin reductions with an overall PSM rate of 27.7% (28.2%, 28.6%, and 26.7% in each group respectively). CONCLUSIONS Clinical and surgical features in our patients did not vary over time. We found a significant reduction of PSM related to surgeons experience in pT2 patients. Contrariwise, the margin status remained stable despite increasing experience in pT3 patients.