Osman Acar

Intracerebral schwannoma: case report and review

A case of intraparenchymal schwannoma of the brain in a 4-year-old girl is presented. Most of the small number of intracranial schwannomas unassociated with cranial nerves, reported have occurred in children or young adults. There is no male or female predominance. Most of the parenchymatous schwannomas are located supratentorially. The presence of a cyst together with the tumor appears to be characteristic of intraparenchymal schwannoma of the brain.

Cerebral salt wasting syndrome

Hyponatremia following acute or chronic central nervous system injury which is due to excessive Na+loss in the urine without an increase in the body fluid, has been described as Cerebral Salt Wasting Syndrome (CSWS). This syndrome is often confused with dilutional hyponatremia secondary to inappropriate ADH secretion. Accurate diagnosis and management are mandatory for to improve the course of the disease.In this study a patient with CSW Syndrome is presented and the treatment and diagnosis of this syndrome are discussed in view of the literature.

The effects of folic acid in the prevention of neural tube development defects caused by phenytoin in early chick embryos.

Study Design. The effects of phenytoin and folic acid on the development of neural tube defects in early chick embryos were studies. Objective. To investigate the effects of folic acid in the prevention of neural tube development defects. Summary of Background Data. Several studies have shown that phenytoin selectively inhibits neural tube closure. Folic acid supplementation has been reported to decrease the occurrence of neural tube defects. Methods. This study shows the effects of folic acid in preventing neural tube development defects caused by phenytoin in chicks based on light microscopy, transmission electron microscopy, and histopathological examination. Forty-five fertile Hubbard Broil eggs, all at Stage 8 (four somite) of development, were divided into three equal groups: Group 1 embryos (n = 15), the control group, were explanted and grown for 18 hours in a nutrient medium (thin albumin). Group 2 embryos (n = 15) were explanted and grown for 18 hours in a nutrient medium containing 500 &mgr;g/mL of phenytoin. Group 3 embryos (n = 15) were explanted and grown for 18 hours in a nutrient medium containing 500 &mgr;g/mL of phenytoin and 0.4 &mgr;g/mL of folic acid. Results. After the incubation period, 86.6% of the control embryos (Group 1) had intact neural tubes; 80% of Group 2 and 46.6% of Group 3 embryos showed neural tube defects. Conclusions. The results of this study suggest that phenytoin causes neural tube defects, whereas folic acid decreases the incidence of neural tube development defects caused by phenytoin in early chick embryos.

Multiple and infected cerebral hydatid cysts. Case report

A case of multiple and infected cerebral hydatid cysts is described. The diagnosis was based on operation and histopatology. So far only two infected cysts have been described in the English literature.

Arachnoid cyst within the fourth ventricle: a case report

The authors report a case of fourth ventricular arachnoid cyst that presented clinically with the criteria of normal pressure hydrocephalus. Only a few cases of intraventricular arachnoid cyst have been recorded in the literature. In our case, a posterior approach was used via a midline suboccipital craniectomy and the cyst was excised.

CT and MR imaging of vertebral osteoblastoma. A report of two cases.

Two patients with spinal osteoblastoma evaluated with computed tomography (CT) and magnetic resonance imaging (MRI) are presented. A brief literature review is added.

Submandibular and Intracranial Hydatid Cyst in an Adolescent

Objectives An unusual case of hydatid disease is reported. Review of the pertinent literature did not reveal any hydatid disease located simultaneously in both the intracranial and submandibular glands. This is the first case with hydatid disease occurring in both locations at the same time.

The penetration of cefoperazone and sulbactam into the lumbar intervertebral discs.

Six patients received 1 g and six other patients received 2 g of cefoperazone and sulbactam 15 minutes before lumbar disc surgery. Liquid chromatographic analysis of disc tissue revealed that only patients receiving the 2-g dose had mean tissue levels above the minimum inhibitory concentration for Staphylococcus aureus and epidermidis.

Epidural thoracal teratoma in a 7-month-old girl.

Abstract Case report.We report a rare case of epidural thoracal teratoma in a 7-month-old girl. A total laminectomy was performed via T6–T8 and the lesion was totally excised. Results and discussion. We describe the radiological, surgical and pathological findings in this patient and review the findings in other reported cases.

INTRAMEDULLARY ABSCESS OF THE SPINAL CORD

We report a rare case of intramedullary spinal cord abscess. The patient was operated on by surgical drainage and appropriate antibiotic therapy. Improvement was seen postoperatively. Significant changes in the presentation, management, and outcome in these more recent cases are emphasized.