Oswy Z. Pereira
Shire plc
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Publication
Featured researches published by Oswy Z. Pereira.
Bioorganic & Medicinal Chemistry Letters | 2004
Laval Chan; Sanjoy K. Das; T. Jagadeeswar Reddy; Carl Poisson; Melanie Proulx; Oswy Z. Pereira; Marc Courchesne; Caroline Roy; Wuyi Wang; Arshad Siddiqui; Constantin G. Yannopoulos; Nghe Nguyen-Ba; Denis Labrecque; Richard Bethell; Martine Hamel; Philippe Courtemanche-Asselin; Lucille L'Heureux; Maud David; Olivier Nicolas; Stéphanie Brunette; Darius Bilimoria; Jean Bedard
The discovery of a novel class of HCV NS5B polymerase inhibitors, 3-arylsulfonylamino-5-phenyl-thiophene-2-carboxylic acids is described. SAR studies have yielded several potent inhibitors of HCV polymerase as well as of HCV subgenomic RNA replication in Huh-7 cells.
Bioorganic & Medicinal Chemistry Letters | 2003
T. Jagadeeswar Reddy; Laval Chan; Nathalie Turcotte; Melanie Proulx; Oswy Z. Pereira; Sanjoy K. Das; Arshad Siddiqui; Wuyi Wang; Carl Poisson; Constantin G. Yannopoulos; Darius Bilimoria; Lucille L'Heureux; Hicham M.A. Alaoui; Nghe Nguyen-Ba
Herein, we describe the structure-activity relationship (SAR) of N,N-disubstituted phenylalanine series of NS5B polymerase inhibitors of hepatitis C. The NS5B polymerase inhibitory activity of the most active compound exhibited an IC(50) of 2.7 microM.
Journal of Medicinal Chemistry | 2003
Laval Chan; T. Jagadeeswar Reddy; Melanie Proulx; Sanjoy Kumar Das; Oswy Z. Pereira; Wuyi Wang; Arshad Siddiqui; Constantin G. Yannopoulos; Carl Poisson; Nathalie Turcotte; Alexandre Drouin; M. Hicham Alaoui-Ismaili; Richard C. Bethell; Martine Hamel; Lucille L'Heureux; Darius Bilimoria; Nghe Nguyen-Ba
Archive | 2008
Christophe Moinet; Liliane Halab; Nathalie Turcotte; Monica Bubenik; Marc Courchesne; Carl Poisson; Oswy Z. Pereira; Paul Nguyen-Ba; Bingcan Liu; Nathalie Chauret; Caroline Cadilhac; Chun Kong Laval Chan
Bioorganic & Medicinal Chemistry Letters | 2004
Constantin G. Yannopoulos; Ping Xu; Feng Ni; Laval Chan; Oswy Z. Pereira; T. Jagadeeswar Reddy; Sanjoy Kumar Das; Carl Poisson; Nghe Nguyen-Ba; Nathalie Turcotte; Melanie Proulx; Lilianne Halab; Wuyi Wang; Jean Bedard; Nicolas Morin; Martine Hamel; Olivier Nicolas; Darius Bilimoria; Lucille L’Heureux; Richard Bethell; Gervais Dionne
Archive | 2003
Chun Kong Laval Chan; Oswy Z. Pereira; Nghe Nguyen-Ba; Ming-Qiang Zhang; Sanjoy Kumar Das; Carl Poisson; Liliane Halab; Thumkunta Jagadeeswar Reddy
Archive | 2002
Chun Kong Laval Chan; Jean Bedard; Sanjoy Kumar Das; Ba Nghe Nguyen; Oswy Z. Pereira; Thumkunta Jagadeeswar Reddy; M. Arshad Siddiqui; Wuyi Wang; Constantin G. Yannopoulos
Archive | 2015
Youssef L. Bennani; Caroline Cadilhac; Sanjoy Kumar Das; Evelyne Dietrich; Michael Gallant; Bingcan Liu; Oswy Z. Pereira; Yeeman Ramtohul; T. Jagadeeswar Reddy; Louis Vaillancourt; Frederic Vallee; Constantin G. Yannopoulos
Archive | 2010
Jean Bedard; Chun Kong Laval Chan; Sanjoy Kumar Das; Ba Nghe Nguyen; Oswy Z. Pereira; Thumkunta Jagadeeswar Reddy; M. Arshad Siddiqui; Wuyi Wang; Constantin G. Yannopoulos; シディキ，エム．，アルシャッド; ダス，サンジョイ，クマール; チャン，チュン，コン，ラバル; バ，ネ ヌエン; ベダード，ジーン; ペレイラ，オズウィー，ゼット．; ヤンノパウロス，コンスタンチン; レディー，トゥムクンタ，ジャガディーズウォー; ワン，ウーイ
Archive | 2003
Chun Kong Laval Chan; Sanjoy Kumar Das; Nghe Nguyen-Ba; Liliane Halab; Bettina Hamelin; Oswy Z. Pereira; Carl Poisson; Melanie Proulx; Thumkunta Jagadeeswar Reddy; Ming-Qiang Zhang
