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Otmane Boussif

Transgene SA

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Publication

Featured researches published by Otmane Boussif.

Journal of Gene Medicine | 2001

Enhanced in vitro and in vivo cationic lipid-mediated gene delivery with a fluorinated glycerophosphoethanolamine helper lipid.

Otmane Boussif; Jérôme Gaucheron; Caroline Boulanger; Catherine Santaella; Hanno V. J. Kolbe; Pierre Vierling

One of the main drawbacks of synthetic, non‐viral gene vectors is their relatively low in vivo efficiency when compared with viral vectors. The present paper describes the use of a partially fluorinated glycerophosphoethanolamine (F‐PE), a close analog of DOPE, which, as a helper lipid with the cationic lipopolyamine pcTG90, increases its in vitro and in vivo gene transfer capability to a larger extent than DOPE.

Bioconjugate Chemistry | 1999

Synthesis of Polyallylamine Derivatives and Their Use as Gene Transfer Vectors in Vitro

Otmane Boussif; Thierry Delair; Catherine Brua; Laurent Veron; and Andrea Pavirani; Hanno V. J. Kolbe

Bioconjugate Chemistry | 2001

In Vitro Cationic Lipid-Mediated Gene Delivery with Fluorinated Glycerophosphoethanolamine Helper Lipids

Jérôme Gaucheron; Caroline Boulanger; Catherine Santaella; Nicolas Sbirrazzuoli; Otmane Boussif; Pierre Vierling

Journal of Medicinal Chemistry | 2000

Lipopolycationic telomers for gene transfer: synthesis and evaluation of their in vitro transfection efficiency.

G. Verderone; N. van Craynest; Otmane Boussif; Catherine Santaella; Rainer Bischoff; Hanno V. J. Kolbe; Pierre Vierling

Archive | 1998

Cationic polymers, complexes associating said cationic polymers with therapeutically active substances comprising at least a negative charge, in particular nucleic acids, and their use in gene therapy

Hanno V. J. Kolbe; Otmane Boussif; Thierry Delair; Laurent Veron

Bioconjugate Chemistry | 2002

Polycationic telomers and cotelomers for gene transfer: synthesis and evaluation of their an vitro transfection efficiency.

Nathalie Van Craynest; Catherine Santaella; Otmane Boussif; Pierre Vierling

Bioconjugate Chemistry | 2002

Polycationic diblock and random polyethylene glycol- or tris(hydroxymethyl)methyl-grafted (co)telomers for gene transfer: synthesis and evaluation of their in vitro transfection efficiency.

Bertrand Le Bon; Nathalie Van Craynest; Otmane Boussif; Pierre Vierling

Archive | 1998

Method for preparing suspension of stable posiplexes

Otmane Boussif; Hanno V. J. Kolbe; Olivier Meyer

Archive | 2001

Non-naturally occurring nucleic acid compositions, their use for the preparation of formulations useful for transfecting a nucleic acid into cells and applications

Otmane Boussif; Pierre Vierling; Catherine Santaella; Jérôme Gaucheron

Archive | 1998

Use of a catonic polymer for the preparation of a complex with nucleic acid and related compositions

Otmane Boussif; Hanno V. J. Kolbe

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Hanno V. J. Kolbe

Transgene SA

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Pierre Vierling

Transgene SA

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Catherine Santaella

Transgene SA

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Laurent Veron

BioMérieux

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Jérôme Gaucheron

University of Nice Sophia Antipolis

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Caroline Boulanger

University of Nice Sophia Antipolis

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Olivier Meyer

Transgene SA

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