Owen McKern

Model compounds for galactose oxidase: The crystal and molecular structure of dimeric (4-methylpyridine-N) (N-salicylidene-tyrosinato-O, N, O')copper(II)

Galactose oxidase is a type II copper protein that contains a square–pyramidal five-coordinate copper center and catalyzes the oxidation of primary alcohols to aldehydes with a concomitant reduction of molecular oxygen. Dimeric (4-methylpyridine-N)(N-salicylidene-tyrosinato-O, N, O′)copper(II), which contains two square–pyramidal five-coordinate copper centers and thus serves as a model for galactose oxidase, crystallizes in the monoclinic space group P21/c with a = 8.914(1) Å, b = 18.415(2) Å, c = 12.802(2) Å, β = 107.70(1)°. The dinuclear unit comprises two four-coordinate units each consisting of the tridentate Schiff base and 4-methylpyridine with a weaker out-of-plane link to the phenolic oxygen atom from the adjoining unit in a typical 4 + 1 distorted square–pyramidal geometry.

catena‐Poly­[[(pyridine‐κN)copper(II)]‐μ‐N‐salicyl­idene­glycinato‐κ4O,N,O′:O′]

The tridentate Schiff base ligand derived from the condensation of salicylxadaldehyde and glycine, in the presence of pyridine, forms the title polymeric square-pyramidal five-coordinate copper complex, [Cu(C5H5N)(C9H7NO3)(C5H5N)], in which the copper centers are linked via the carboxyl O atoms of neighboring groups occupying the apical site.

Aqua(pyridine-kN)(N-salicylidenetyrosinaot-k3 O,N,O')copper (II)

The tridentate Schiff base ligand derived from the condenxadsxadation of salicylxadaldehyde and dl-tyrosine, in the presence of pyridine, forms a square-pyramidal five-coordinate Cu complex, [Cu(C16H13NO4)(C5H5N)(H2O)], with a water molxadecule occupying the apical site.

(Piperidine-kN)[N-(salicylidene)phenylalaninato-k3 0,N,0']copper(II)

The tridentate Schiff base ligand derived from the condensxadation of salicylxadaldehyde and l-phenylxadalanine, in the presence of piperidine, when reacted with copper sulfate pentahydrate, forms a polymeric square pyramidal five-coordxadinate copper complex, [Cu(C17H14O3)(C4H10N2)]. The axial position of the square pyramid is occupied by the carboxyl O atoms of a neighboring molxadecule.

(Piperidine-κN)[N-(salicyl­idene)­phenyl­alaninato-κ3O,N,O′]copper(II)

The tridentate Schiff base ligand derived from the condensxadation of salicylxadaldehyde and l-phenylxadalanine, in the presence of piperidine, when reacted with copper sulfate pentahydrate, forms a polymeric square pyramidal five-coordxadinate copper complex, [Cu(C17H14O3)(C4H10N2)]. The axial position of the square pyramid is occupied by the carboxyl O atoms of a neighboring molxadecule.

Aqua­(pyridine-κN)(N-salicyl­idene­tyrosinato-κ3O,N,O′)copper(II)

The tridentate Schiff base ligand derived from the condenxadsxadation of salicylxadaldehyde and dl-tyrosine, in the presence of pyridine, forms a square-pyramidal five-coordinate Cu complex, [Cu(C16H13NO4)(C5H5N)(H2O)], with a water molxadecule occupying the apical site.

Aqua(pyridine-κN)(N-salicylidenetyrosinato-κ3O,N,O′)copper(II)

The tridentate Schiff base ligand derived from the condenxadsxadation of salicylxadaldehyde and dl-tyrosine, in the presence of pyridine, forms a square-pyramidal five-coordinate Cu complex, [Cu(C16H13NO4)(C5H5N)(H2O)], with a water molxadecule occupying the apical site.

(Piperidine-κN)[N-(salicylidene)phenylalaninato-κ3O,N,O′]copper(II)

The tridentate Schiff base ligand derived from the condensxadation of salicylxadaldehyde and l-phenylxadalanine, in the presence of piperidine, when reacted with copper sulfate pentahydrate, forms a polymeric square pyramidal five-coordxadinate copper complex, [Cu(C17H14O3)(C4H10N2)]. The axial position of the square pyramid is occupied by the carboxyl O atoms of a neighboring molxadecule.