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Featured researches published by P. Noirhomme.


Cardiovascular Surgery | 1996

Free internal mammary artery graft in myocardial revascularization.

Robert Verhelst; Pierre-Yves Etienne; G. El Khoury; P. Noirhomme; Jean Rubay; R. Dion

Between August 1986 and March 1993, 124 patients (102 men; mean age of 59 years) underwent myocardial revascularization with the use of at least one free internal mammary artery (FIMA). This group represents 4.5% of the 2725 coronary bypasses performed during the same period. Seventy-six patients (61%) had suffered from at least one previous myocardial infarction. Forty-five patients (36%) had unstable angina; three-vessel disease was found in 100 cases (80.5%) and a left ventricular ejection fraction lower than 0.4 in 22 (17.7%). There were 18 (14.5%) redo procedures and 90 (72.5%) bilateral internal mammary artery (IMA) grafts. The reasons for using a FIMA were: too short an internal mammary artery pedicle in 83 patients, IMA injury at harvesting in 30 patients and post-bypass ischaemia in areas grafted with pedicled IMA (PIMA) in 11 patients. Cardiopulmonary bypass, moderate hypothermia (30 degrees C) and crystalloid anterograde and retrograde cardioplegia were used in all cases. Sixty-seven FIMA grafts were anastomosed directly to the ascending aorta; 57 were sutured via a saphenous hood using a running suture of polypropylene 7/0 and three were anastomosed end-to-end to a PIMA graft. FIMA grafts were directed to the left anterior descending (34%), the circumflex (37%) and the right coronary artery (29%). In total, 179 anastomoses were constructed using 127 FIMA, 136 using PIMA and 158 using saphenous veins (3.8 anastomoses per patient). Hospital mortality and postoperative myocardial infarction rates were 5.6% (seven patients) and 3.2% (four patients), respectively. Cardiac-related mortality was 3.2% (four patients); three of these four patients had been operated on for evolving infarction and one underwent a redo procedure. Four of the 117 survivors died later on; in two, it was cardiac-related and a result of global heart failure at 9 and 12 months. Of the 113 remaining patients, 106 are symptom free after a mean follow-up of 28.2 (range 3-84) months. Fifty-nine patients (50.4%) were restudied by angiography at a mean interval of 15 months. Patency rates of FIMA anastomosed either directly to the aorta or via a saphenous hood were 82.8 or 89.7%, respectively. Patency rates of FIMA directed to the left anterior descending, the circumflex and the right coronary artery were 85.7, 88 and 83.3%, respectively. Global FIMA patency was 86.4%, while global PIMA patency was 100%. The FIMA mid-term patency rates compare unfavourably with those of PIMA: FIMA should therefore be restricted to the cases where PIMA or other pedicled arterial grafts are unavailable.


Annals of Vascular Surgery | 2009

Endovascular treatment of acute aortic isthmic rupture: concerning midterm results.

Parla Astarci; Valérie Lacroix; David Glineur; A. Poncelet; Jean Rubay; G. El Khoury; P. Noirhomme; R. Verhels

BACKGROUND We evaluated midterm results of endovascular management of traumatic aortic isthmic ruptures. METHODS Between 2001 and 2008, 10 patients (seven males, mean age 38 years) underwent endovascular treatment of an acute aortic rupture. Eight procedures were emergent, with four cases of hemodynamic instability with Glasgow scores of 3, 5, and 7. Associated traumas were severe brain, liver, and pelvic bone injuries. All procedures were performed with transoesophageal echocardiography monitoring. We used two AneuRx and nine Medtronic Talent or Valiant stent grafts. RESULTS All patients survived their traumatic isthmic rupture. In nine patients, stent-graft deployment was successful. One patient experienced a distal migration needing a laparotomy and deployment of an additional new thoracic stent graft. The mean intensive care unit stay was 48 hr (range 24-168). The mean hospital stay was 11 days (range 8-43). All patients were controlled clinically and by contrast computed tomography (CT) according to the EUROSTAR protocol. There were no endoleaks, stent graft-related complications, or late deaths during a mean follow-up of 49 months. The control CT showed a lack of apposition of the proximal part of the stent graft at the inner curve of the aortic arch in three patients. CONCLUSION The midterm results of endovascular treatment of acute traumatic aortic isthmic rupture are encouraging and compare favorably to the surgical approach. Late follow-up is required to exclude possible stent-graft complications, especially in young patients with angulated aortic arches.


80th Annual Scientific Session of the American-Heart-Association | 2007

Intraoperative transoesophageal echocardiographic predictors of recurrent aortic regurgitation after aortic valve repair

Jean-Benoît Le Polain De Waroux; Bernhard Gerber; Gebrine El Khoury; Jean-Louis Vanoverschelde; Anne-Catherine Pouleur; Céline Goffinet; David Vancraeynest; Agnes Pasquest; P. Noirhomme


Circulation | 2017

Twenty-Year Outcome After Mitral Repair Versus Replacement for Severe Degenerative Mitral Regurgitation

Siham Lazam; Jean-Louis Vanoverschelde; Christophe Tribouilloy; Francesco Grigioni; Rakesh M. Suri; Jean-François Avierinos; Christophe de Meester; Andrea Barbieri; Dan Rusinaru; Antonio Russo; Agnes Pasquet; Hector I. Michelena; Marianne Huebner; Joseph Maalouf; Marie-Annick Clavel; Catherine Szymanski; Maurice Enriquez-Sarano; H. Michelina; H. Poulain; Jean-Paul Remadi; Gilles Touati; Faouzi Trojette; Elena Biagini; R. Di Bartolomeo; F.M. Ferlito; Giuseppe Marinelli; Davide Pacini; Ferdinando Pasquale; Claudio Rapezzi; Carlo Savini


Interactive Cardiovascular and Thoracic Surgery | 2014

095THE ROLE OF ANNULUS DIMENSION AND ANNULOPLASTY IN TRICUSPID AORTIC VALVE REPAIR

L. de Kerchove; Stefano Mastrobuoni; M. O'Keefe; Parla Astarci; Alain Poncelet; Jean Rubay; P. Noirhomme; G. El Khoury


Canadian Journal of Cardiology | 2014

LONG-TERM OUTCOMES OF AORTIC VALVE REPAIR: A MULTICENTER STUDY

M. Boodhwani; Tarek Malas; L. de Kerchove; T. Mesana; P. Noirhomme; G. El Khoury


Interactive Cardiovascular and Thoracic Surgery | 2013

097AORTIC VALVE RECONSTRUCTION WITH A PATCH: INDICATION, TECHNIQUES AND DURABILITY

Z. Mosala Nezhad; Jawad Hechadi; L. de Kerchove; David Glineur; P. Noirhomme; Jean Rubay; G. El Khoury


Interactive Cardiovascular and Thoracic Surgery | 2013

188CLINICAL AND ANGIOGRAPHIC COMPARISON OF BILATERAL INTERNAL THORACIC ARTERY CONFIGURATIONS: Y COMPOSITE GRAFTING IS SUPERIOR TO IN SITU

G. de Beco; G. El Khoury; P. Noirhomme; L. de Kerchove; Parla Astarci; Pierre-Yves Etienne; David Glineur


Canadian Journal of Cardiology | 2011

662 Effect of Left ventricular size and function on outcome following aortic valve repair for aortic insufficiency

M. Boodhwani; Talal Al-Atassi; L. de Kerchove; David Glineur; T. Mesana; P. Noirhomme; G. El Khoury


Anales de Cirugía Vascular | 2009

Tratamiento endovascular de la rotura aguda del istmo aórtico: resultados a medio plazo

Parla Astarci; Valérie Lacroix; David Glineur; A. Poncelet; Jean Rubay; G. El Khoury; P. Noirhomme; R. Verhels

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G. El Khoury

Cliniques Universitaires Saint-Luc

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Jean Rubay

Cliniques Universitaires Saint-Luc

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L. de Kerchove

Cliniques Universitaires Saint-Luc

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Parla Astarci

Cliniques Universitaires Saint-Luc

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David Glineur

Cliniques Universitaires Saint-Luc

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A. Poncelet

Université catholique de Louvain

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Valérie Lacroix

Cliniques Universitaires Saint-Luc

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Agnes Pasquet

Cliniques Universitaires Saint-Luc

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Anne-Catherine Pouleur

Université catholique de Louvain

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Bernhard Gerber

Cliniques Universitaires Saint-Luc

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