P. P. Gupta

Spontaneous Aortic Atherosclerosis in Sheep

Aortas of 334 sheep 6 months to 6 years old were stained with Sudan IV. Sudanophilic lesions resembling early fatty streaks of man were detected in 50% of these aortas. Metastatic calcification was seen in eight (2.3%) aortas.

Intimai Changes in the Coronary Arteries of Indian Water Buffaloes (Bubalus bubalis)

Of 75 Indian water buffaloes (Bubalus bubalis) examined, 14 6-year-old or older buffaloes had early atherosclerotic lesions in the coronary arteries. These lesions resembled fatty streaks seen in man. Ageing changes and gross and microscopic features of the fatty streaks in the vessels resembled those described in the corresponding arteries of man.

Phycomycotic Gastritis in Buffalo Calves (Bubalis bubalis)

Mycotic gastritis, primarily caused by Rhizopus sp. was seen in six buffalo calves (7–13 days old) at postmortem examination. The predominant lesions were numerous raised ulcers in which were hyphae of Rhizopus. In three calves, Candida organisms were also present superficially in the ulcers. Other changes in the mucosa were severe congestion, haemorrhage, thrombosis, necrosis, and infiltration by lymphocytes and neutrophils. Both Rhizopus and Candida were highly pathogenic to rabbits when inoculated intravenously. The disease could not be reproduced experimentally by feeding of Rhizopus orally to rabbits and calves.

Bronchogenic Carcinoma in Indian Water Buffaloes (Bubalus bubalis)

The bronchogenic carcinoma, though rare in animals, has been reported in the dog, ox, horse, sheep, cat, dog and chicken [I-31. This is apparently the first report of this type of tumour in the buffalo. During a 12-month period lung tumours were found in five animals: four buffaloes and one domestic cow. All were aged females. The tumour in one buffalo and the cow was an incidental postmortem finding, and the other tumours were found in slaughtered beasts. In all cases both lungs had grey-white firm nodules that were mainly around airways and varied from 1 to 5 cm in diameter. Metastatic nodules occurred in regional nodes in two of the four animals, but not in other sites. The primary and secondary nodules were composed of irregular alveolar or tubular structures lined by one to several layers of anaplastic epithelial cells. In places there was a resemblance to small bronchioles. In one animal the spaces in the tumour were lined by neoplastic squamous epithelial cells. There was usually abundant supporting fibrous stroma.