P. S. N. Reddy

A New Synthesis of 2-Aryl-2H-Pyrazino[2,1-B]quinazolin-3,6[1H,4H)-diones

Abstract A new synthesis of 2-aryl-2H-pyrazino [2,1-b] quinazolin-3,6(1H, 4H)-diones starting from 2-chloromethylquinazolin-4(3H)-one is described.

Microwave Assisted Oxidation of Aromatic Aldehydes

Abstract Aromatic aldehydes are converted to carboxylic acids in 6-8 minutes, and in the absence of any external promoting agent, under microwave irradiation conditions.

UNEXPECTED FORMATION OF CYCLIC HYDROXAMIC ACIDS FROM O-(2-AMINOBENZOYL) HYDROXYLAMINE

Abstract Cyclic hydroxamic acids 3 and 4 are the unexpected products in the reaction of 0-(2-aminobenzoyl) hydroxylamine 1 and orthoesters, acid chlorides, ethyl chloroformate.

A New Synthesis of 1,2,4-Triazino[6, 1-B]Quinazolin-4,10-diones

Abstract The reaction of 2-ethoxycarbonyl-3-aminoquinazolin-4-one (1) with aliphatic amines, ammonia and hydrazine hydrate gave 2-alkylamino/amino/hydrazinocarbonyl-3-aminoquinazolin-4-ones (2) which on reaction with ortho-esters resulted in 3, 4 and 5 respectively.

Synthesis of Some Novel 1,3,4‐Oxadiazol‐2‐yl‐4(3H)‐quinazolinones

Abstract N‐1‐Aroyl‐2‐{[(3‐methyl‐4(3H)‐quinazolinone‐2‐yl)methyl]anilino} ethano hydrazides (4), prepared from 2‐phenylaminomethyl‐3‐methyl‐4(3H)‐quinazolinone (1), underwent PPA‐catalyzed cyclization the to title compounds 5 in 51–67% yield.

Microwave‐Induced Conversion of Acid Hydrazides to N,N′‐Diacylhydrazines in Solvent‐Free Conditions

Abstract A new and efficient method of converting acid hydrazides 1 to the corresponding N,N′‐diacylhydrazines 2 under microwave irradiation and in solvent‐free conditions has been described.

CYCLIC HYDROXAMIC ACIDS AS OXYGENATING AGENTS – CONVERSION OF IMINES TO ANILIDES

Cyclic hydroxamic acid mediated functional group modification of an imine to anilide is reported.