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Featured researches published by P.T. V. M. de Jong.


Vision Research | 1995

1142 Prevalence and causes of blindness in subjects of 55 years and older: The Rotterdam study

C.C.W. Klaver; R.C.W. Wolfs; J.R. Vingerling; D. Dielemans; A. Hofman; P.T. V. M. de Jong

lbpauz To study the prevalence aad causes of blindness and low vision in a middle-aged and elderly population of the NOtlWlands. MetlrodrIn a single center prospective follow-up study in Rotterdam, 6178 subjects of 55 years and older underwent a complete ophthalmological examination. The grade of visual impairment was classified according to WHO-standards: subjects with best-corrected visual acuity c 0.05 in the better eye were defined as blind, subjects with visual acuity < 0.3 in the better eye were defined as affected by low vision. Ruu& We identified 32 subjects who were blind io both eyes. Overall prevalence of blindness was 0.5%. raaghg from 0.1% in subjects under 60 years to 3.9% in subjects of 85 years and older. Prevalence of low vision was 1.4%, ranging from 0.2% to 12.0%. Major causes of blindness were agerelated macular degeneration (55%). myopic degeneration (7%), glaucoma (7%), cataract (7%), and a combination of the above pathology (17%). conduh~ Age-related macular degeneration is by far the major cause of severe visual impairment in this predominantly white population of 55 years and older. ANTERIOR SRGMEVT EYR INFECTIONS DUGNOSTIC TRENDR IN A umvERRITYEYEcLlN1c


Investigative Ophthalmology & Visual Science | 2010

A Genome-Wide Association Study of Glaucomatous Optic Neuropathy

Wishal D. Ramdas; L.M. E. van Koolwijk; Mohammad Kamran Ikram; Hans G. Lemij; R. C. W. Wolfs; P.T. V. M. de Jong; Nomdo M. Jansonius; Johannes R. Vingerling; C. C. W. Klaver; C. M. van Duijn


Investigative Ophthalmology & Visual Science | 2009

Incidence of Glaucomatous Visual Field Loss: A Ten-Year Follow-Up From the Rotterdam Study

Monika A. Czudowska; Roger C. W. Wolfs; Albert Hofman; P.T. V. M. de Jong; Johannes R. Vingerling; Nomdo M. Jansonius


Investigative Ophthalmology & Visual Science | 2009

Definition of Glaucomatous Optic Neuropathy for Epidemiological Studies Based on the Heidelberg Retina Tomograph (hrt3) - The Rotterdam Study

Wishal D. Ramdas; R. C. W. Wolfs; A. Hofman; P.T. V. M. de Jong; Johannes R. Vingerling; N. M. Jansonius


Investigative Ophthalmology & Visual Science | 2009

Saturated Fatty Acids and Age Related Macular Degeneration

Astrid E. Fletcher; Ian S. Young; Usha Chakravarthy; P.T. V. M. de Jong; Mati Rahu; Johan H. Seland; G. Soubrane; L. Tomazzoli; Fotis Topouzis; J. Vioque


Investigative Ophthalmology & Visual Science | 2007

Microarray Analysis of Laser Dissected Photoreceptor and RPE Cells as a Tool to Select Novel Positional Candidate Retinal Disease Genes

Judith C. Booij; S. van Soest; N. Yeremenko; J. F. F. Brinkmann; Anke H. W. Essing; G.C. de Wit; P.T. V. M. de Jong; A.A.B. Bergen


Investigative Ophthalmology & Visual Science | 2007

Gene Expression and Lipofuscin Accumulation in an in vitro Model for Age- Related Macular Degeneration

D. C. Baas; S. van Soest; Theo G. M. F. Gorgels; P.T. V. M. de Jong; J. Stap; Arthur A. B. Bergen


Investigative Ophthalmology & Visual Science | 2006

Photoreceptor Gene Expression Alterations in Aging and Early Stage of Age Related Macular Degeneration

N. Yeremenko; S. van Soest; G.M. J. de Wit; Anke H. W. Essing; W. Kamphuis; P.T. V. M. de Jong; A.A.B. Bergen


Investigative Ophthalmology & Visual Science | 2005

Identification of mutations in the CRB1, RPE65, RETGC1, AIPL1, and RPGRIP1 genes in a cohort of 38 patients with juvenile retinitis pigmentosa

Judith C. Booij; Ralph J. Florijn; J.B. ten Brink; Willem Loves; Françoise Meire; M.J. van Schooneveld; P.T. V. M. de Jong; A.A.B. Bergen


Investigative Ophthalmology & Visual Science | 2005

Does VMD2 Genotype Predict Visual Outcome in Patients With Best Vitelliform Dystrophy

C. C. W. Klaver; Judith C. Booij; J.B. ten Brink; P.T. V. M. de Jong; M.J. van Schooneveld; A.B. B. Bergen

Collaboration


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A.A.B. Bergen

Royal Netherlands Academy of Arts and Sciences

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S. van Soest

Netherlands Institute for Neuroscience

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J.B. ten Brink

Netherlands Institute for Neuroscience

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C. C. W. Klaver

Erasmus University Medical Center

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Judith C. Booij

Royal Netherlands Academy of Arts and Sciences

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Anke H. W. Essing

Royal Netherlands Academy of Arts and Sciences

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Nomdo M. Jansonius

University Medical Center Groningen

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R. C. W. Wolfs

Erasmus University Rotterdam

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