P. ten Broecke

Isolated Lung Perfusion for the Treatment of Pulmonary Metastatic Disease: a Review

Abstract Isolated lung perfusion with chemotherapeutic agents is an experimental technique for the treatment of lung metastatic disease from certain solid tumours. The technique had already been developed in the late 1950s but underwent a revival in the early 1980s. By that time, experimental work in large and small animals induced extensive clinical work with different agents such as doxorubicin, tumour necrosis factor, melphalan and cisplatin for which safety profiles and maximal tolerated doses were defined. A review of current work is presented in this article.

Preservation of myocardial function after coronary surgery with sevoflurane anesthesia: is timing of administration involved?: A-195

of change. The best slope for dose-response curve was with Pmax and Pmaxi. for ethical reason the dose of dobutamine was limited to 10 mcg/kg/mn and we could not clearly showed a plateau for dose-response curve. Among all different methods used for evaluation of LV systolic function available with TEE, peak power pre-load corrected seems to be most accurate method to monitor change of inotropic state.