Padma Paul

Intracameral amphotericin B injection in the management of deep keratomycosis

Purpose. To report the use of intracameral amphotericin B in the management of deep keratomycosis. Methods. Four patients with deep keratomycosis unresponsive to conventional medical treatment underwent repeated intracameral injections of 5 &mgr;g amphotericin B in 0.1 mL 5% dextrose through a paracentesis. Three to 13 intracameral injections were given to each patient over 6 to 36 days. Results. Three of the four patients had complete resolution of the ulcer. The fourth patient perforated and required evisceration. Conclusion. Preliminary experience suggests that intracameral injections of amphotericin B may have a role in the management of deep keratomycosis.

use of Pattern Standard Deviation Instead of Corrected Pattern Standard Deviation in Anderson's Criteria

Purpose: To determine whether the use of pattern standard deviation instead of corrected pattern standard deviation, as part of Andersons criteria, makes a difference in categorizing a single field printout using the full threshold strategy on the Humphreys Field Analyzer. Materials and Methods: Forty‐eight patients with glaucomatous field defects of varying severity underwent full threshold perimetry on the Humphreys Field Analyzer. The third field of one eye was used for the study. The agreement between CPSD and PSD alone was determined. Each field was then categorized using Andersons criteria first using CPSD and then PSD. The kappa statistic was used to determine agreement in both situations. Results: The agreement between CPSD and PSD alone, as determined by kappa, was 0.77. The kappa statistic for categorization using Andersons criteria was 0.82; the weighted kappa was 0.92. Conclusion: There was almost perfect agreement using the PSD instead of CPSD as part of Andersons criteria. This substitution seems valid for the spectrum of field defects used in this series, at least for the full threshold programs.