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Journal of The Chemical Society-perkin Transactions 1 | 1986

Ring transformation of 1-[(1,2,4-oxadiazol-3-yl)methyl]isoquinolines into 2-acylaminopyrazolo[5,1-a]isoquinolines

Imre Bata; Gergely Heja; Pal Kiss; Dezso Korbonits

Selective reduction of 1-[(1,2,4-oxadiazol-3-yl)methyl]-3,4-dihydroisoquinolines (8) gives the tetrahydro derivatives (12) which readily isomerize to 2-acylaminopyrazolo[5,1-a]isoquinolines (13). Compounds (13) were also obtained by reaction of the isoquinolinylacetamide oxime (11) with esters (6). A comparision of ring transformations in the series of compounds (8) and (12) indicated that both followed the same mechanism. This provided further support to the proposed1a extension of the Type-2 Boulton–Katritzky scheme.


Chemische Berichte | 1984

Synthese von 4‐Aminopyrimidinen aus 1,2,4‐Oxadiazolen, I. Eine neue, allgemeine Methode zur Herstellung von 4‐Aminochinazolinen und deren Heteroanaloga

Dezso Korbonits; Pal Kiss; K. Simon; Pál Kolonits


Archive | 1989

Diphenkylpropylamines for the therapy of heart disease

Dezso Korbonits; Pal Kiss; Laszlo Szekeres; Gyula Papp; Gabor Kovacs; Andrea Sántáné Csutor; Sandor Virag; Eva Udvari; Imre Bata; Katalin Marmarosi nee Kellner; Laszlo Tardos; Peter Kormoczy; Vera Gergely; Zoltan Vargai


Archive | 1982

Process for the preparation of an inclusion complex of N-(1--phenylethyl)-3,3-diphenylpropylamine and the hydrochloride thereof respectively with cyclodextrin

Jozsef Szejtli; Agnes Stadler nee Szoke; Maria Vikmon nee Kiraly; Dezso Korbonits; Sandor Virag; Istvan Turcsan; Pal Kiss


Chemische Berichte | 1987

Synthesis of 4‐Aminopyrimidines from 1,2,4‐Oxadiazoles, II A General Method for the Preparation of 4‐Substituted 6,7‐Dihydro‐9,10‐dialkoxy‐2H‐pyrimido[6,1‐a]isoquinolin‐2‐imine Hydrochlorides

Dezső Korbonits; Pal Kiss; Imre Bata; Gergely Heja; K. Simon; Pál Kolonits


Journal of Heterocyclic Chemistry | 1973

Mannich-type reactions of an isobasic isoquinoline†

KáLmán Iiarsányi; Pal Kiss; Dezsö Dr. Dipl.-Ing. Chem. Korbonits


Archive | 1983

Theophyllinyl-alkyl-oxadiazoles, process for the preparation thereof and pharmaceutical compositions containing same

Dezso Korbonits; Maria Szomor nee Wundele; Gergely Heja; Ida Szvoboda nee Kanzel; Pal Kiss; Csaba Gönczi; Endre Palosi; Gabor Kovacs; Judit Kun; Emil Minker; Sandor Virag; Gyula Sebestyen; Tamas Szuts


Archive | 1979

Sulfur-containing benzimidazole derivatives

Csaba Gönczi; Dezso Korbonits; Pal Kiss; Endre Palosi; Gergely Heja; Ida Szvoboda nee Kanzel; Judit Kun; Maria Szomor nee Wundele; Gyorgy Kormoczi; Andras Dr Kelemen


Archive | 1987

Diphenylpropylamine derivatives, their preparation and their pharmaceutical use

Dezso Korbonits; Pal Kiss; Laszlo Szekeres; Gyula Dr Papp; Gabor Kovacs; geb. Csutor Andrea Sánta; Sandor Virag; Eva Udvari; Imre Bata; geb. Kellner Katalin Mármarosi; Laszlo Tardos; Peter Kormoczy; Vera Gergely; Zoltan Vargai


Archive | 1983

Theophyllin derivatives, and process for their preparation

Dezsö Dr. Dipl.-Ing. Chem. Korbonits; Geb Wundele Szomor; Gergely Dr. Dipl.-Ing. Chem. Héja; Geb Kanzel Szvoboda; Pal Kiss; Csaba Gönczi; Endre Palosi; G. Kovács; Judit Dipl Ing Chem Kun; Emil Minker; Sandor Virag; Gyula Sebestyen; Tamas Szuts

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