Palle V. R. Acharyulu
Dr. Reddy's Laboratories
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Featured researches published by Palle V. R. Acharyulu.
Synthetic Communications | 2005
C. M. Haricharan Raju; P. Naga Lakshmi; Ch. Srinivas; G. Om Reddy; Palle V. R. Acharyulu
Abstract Ibuprofen piconol synthesis has been described. The use of solid catalyst has demonstrated green chemistry approach with promoted atom economy of 94% compared to the reported 68%. †DRL Publication No: 430.
Synthetic Communications | 2009
Palle V. R. Acharyulu; P. K. Dubey; P. V. V. Prasada Reddy; Thatipally Suresh
Abstract Stereoselective diazotization of (S)-2-amino-2-phenyl acetic acid (L-phenyl glycine) (4) with NaNO2 in 6% H2SO4 in a mixture of acetone and water gave optically pure (S)-2-hydroxy-2-phenyl acetic acid (L-mandelic acid) (5). Esterification, gave (S)-2-hydroxy-2-phenyl acetic acid esters (6). The latter was treated with chloroacetyl chloride in the presence of triethylamine (TEA) in dichloromethane (DCM) to yield (S)-2-chloroacetyloxy phenyl acetic acid ester (2). In another sequence, the reaction of 2-(chloromethyl)-3-arylquinazolin-4(3H)-one (9) treated with N-Boc piperazine, followed by deprotection of the Boc group, to obtain 3-aryl-2-((piperazin-1-yl)methyl) quinazolin-4(3H)-one (3). Reaction of 2 with 3 in the presence of K2CO3 and KI gave the title compound, 2-(2-(4-((3,4-dihydro-4-oxo-3-arylquinazolin-2-yl)methyl)piperazin-1-yl) acetoyloxy)-2-phenyl acetic acid esters (1). The structures of all the new compounds obtained in the present work are supported by spectral and analytical data.
Synthetic Communications | 2008
C. M. Haricharan Raju; P. K. Dubey; Palle V. R. Acharyulu
Abstract The first example of pyrrolidine‐based room‐temperature chiral ionic liquids using 2‐aminobutanol as chiral auxiliary is described.
Journal of Pharmaceutical and Biomedical Analysis | 2004
B.M. Rao; R. Ravi; B. Shyam Sundar Reddy; S. Sivakumar; I. Gopi Chand; K. Praveen Kumar; Palle V. R. Acharyulu; G. Om Reddy; M.K. Srinivasu
Archive | 2005
Palle V. R. Acharyulu; C. M. Raju
Organic Process Research & Development | 2004
Ch. Srinivas; C. M. Haricharan Raju; Palle V. R. Acharyulu
Arkivoc | 2008
Palle V. R. Acharyulu; P. K. Dubey; P. V. V. Prasada Reddy; Thatipally Suresh
Journal of Inclusion Phenomena and Macrocyclic Chemistry | 2010
T. Lakshmi Kumar; Pooja Guleria; Peddy Vishweshwar; A. Sivalakshmidevi; J. Moses Babu; K. Vyas; Palle V. R. Acharyulu; N. M. Sekhar; B. Selva Kumar
Archive | 2013
Thatipally Suresh; Palle V. R. Acharyulu; P. K. Dubey
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry | 2010
Palle V. R. Acharyulu; P. K. Dubey; P. V. V. Prasada Reddy; Thatipally Suresh