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Dive into the research topics where Pamela A. Chambers is active.

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Featured researches published by Pamela A. Chambers.


Journal of Biological Chemistry | 2001

Identification, Substrate Specificity, and Inhibition of theStreptococcus pneumoniae β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH)

Sanjay S. Khandekar; Daniel Robert Gentry; Glenn S. Van Aller; Patrick Vernon Warren; Hong Xiang; Carol Silverman; Michael L. Doyle; Pamela A. Chambers; Alex K. Konstantinidis; Martin Brandt; Robert A. Daines; John T. Lonsdale


Journal of Pharmacology and Experimental Therapeutics | 2001

Pharmacology of SB-273779, a Nonpeptide Calcitonin Gene-Related Peptide 1 Receptor Antagonist

Nambi Aiyar; Robert A. Daines; Jyoti Disa; Pamela A. Chambers; Charles F. Sauermelch; Marie-J. Quiniou; Nassirah Khandoudi; Bernard Gout; Stephen A. Douglas; Robert N. Willette


Archive | 1998

4-sulfinyl benzamides as calcitonin gene-related peptide receptor antagonists

Robert A. Daines; Pamela A. Chambers


Archive | 1992

Pyridine compounds for treating leukotriene-related diseases

Pamela A. Chambers; Robert A. Daines; Dalia R. Jakas; William Dennis Kingsbury; Israil Pendrak


Journal of Medicinal Chemistry | 1996

(E)-3-[6-[[(2,6-Dichlorophenyl)thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2- propenoic Acid: A High-Affinity Leukotriene B4 Receptor Antagonist with Oral Antiinflammatory Activity

Robert A. Daines; Pamela A. Chambers; James J. Foley; Don E. Griswold; William Dennis Kingsbury; Lenox D. Martin; Dulcie B. Schmidt; Kelvin K. C. Sham; Henry M. Sarau


Journal of Organic Chemistry | 1995

Improved Synthesis of RG-14893, a High-Affinity Leukotriene B4 Receptor Antagonist, via a Photochemical Wolff Rearrangement

Israil Pendrak; Pamela A. Chambers


Journal of Medicinal Chemistry | 1994

(E)-3-[[[[6-(2-carboxyethenyl)-5-[[8-(4- methoxyphenyl)octyl]oxy]-2-pyridinyl]-methyl]thio]methyl]benzoic acid and related compounds: high affinity leukotriene B4 receptor antagonists.

Robert A. Daines; Pamela A. Chambers; Eggleston Ds; James J. Foley; Don E. Griswold; Haltiwanger Rc; Dalia R. Jakas; William D. Kingsbury; Lenox D. Martin; Israil Pendrak


Journal of Medicinal Chemistry | 1993

Trisubstituted pyridine leukotriene B4 receptor antagonists: synthesis and structure-activity relationships.

Robert A. Daines; Pamela A. Chambers; Israil Pendrak; Dalia R. Jakas; Henry M. Sarau; James J. Foley; Dulcie B. Schmidt; William D. Kingsbury


Journal of Medicinal Chemistry | 1993

(E)-3-[[[[6-(2-carboxyethenyl)-5-[[8-(4- methoxyphenyl)octyl]oxy]-2-pyridinyl]-methyl]thio]methyl]benzoic acid: a novel high-affinity leukotriene B4 receptor antagonist

Robert A. Daines; Pamela A. Chambers; Israil Pendrak; Dalia R. Jakas; Henry M. Sarau; James J. Foley; Dulcie B. Schmidt; Don E. Griswold; Lenox D. Martin; Maritsa N. Tzimas


Journal of Medicinal Chemistry | 1993

Additions and Corrections - (E)-3-[[[[[6-(2-Carboxyethenyl)-5-[[8-(4-methoxyphenyl)octy-1]oxy]-2-pyridinyl]methyl]thio]methyl]benzoic Acid: A Novel High-Affinity Leukotriene B4Receptor Antagonist.

Robert A. Daines; Pamela A. Chambers; Israil Pendrak; Dalia R. Jakas; Henry M. Sarau; James J. Foley; Dulcie B. Schmidt; Don E. Griswold; Lenox D. Martin; Maritsa N. Tzimas; William D. Kingsbury

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