Paolo Missori

Long-term results of the surgical treatment of spinal dermoid and epidermoid tumors

The clinical findings and the results of surgical treatment in 16 patients with spinal dermoid or epidermoid tumors are reported. In 9 patients the tumor capsule adhered so tightly to the nervous tissue that part of it was left in situ. In a follow-up study ranging from 5 to 30 years with a mean of 14.2 years only 1 patient had a recurrence of the tumor and 10 patients resumed a normal working life.

Management of intramedullary tumours in children

SummaryClinical presentation, diagnosis, surgical technique and results of 25 cases of intramedullary tumours in patients under 16 years of age are analyzed. Pre-operative spinal deformity was present in 9 patients. Surgery was performed in all. After multilaminectomy with preservation of the intervertebral joints, total removal of the lesion was achieved in 11 patients and subtotal removal in 14 others. After surgery, external immobilization lasting an average period of 5 years was instituted in all patients. Postoperative radiation therapy was performed in 11 cases (5 “high grade” astrocytomas, 5 ependymomas, 1 glioblastoma). There were 11 recurrences: 4 of which (2 ependymomas and 2 “low grade” astrocytomas) were treated surgically, 7 (5 “high grade” astrocytomas, 1 glioblastoma, 1 oligodendroglioma) with palliative radiation treatment. Six patients eventually developed postlaminectomy spinal deformities as diagnosed roentgenographically 6 to 50 months postoperatively. Of the 16 patients still alive, 7 did not present relevant neurological deficit, 1 presented a monoparesis, while the other 8 presented invalidating deficits. Surgical treatment did not differ from that employed in the intramedullary tumours in the adult: radical resection is indeed the optimal therapeutic origin. The risk of radiation therapy are greater in children: it is crucial to limit radiation therapy to only some histotypes. The incidence of spinal column deformity after multilevel laminectomy is greater in young patients. It is advisable to implement prevention of spinal deformities by postoperative external immobilization and constant follow-up so as to detect early changes of spinal stability.

Chemical meningitis in ruptured intracranial dermoid. Case report and review of the literature

Abstract A rare case of ruptured frontal dermoid tumor with typical magnetic resonance imaging and computed tomography appearances and presenting with chemical meningitis is reported.

Giant intracranial mucocele secondary to osteoma of the frontal sinuses: Report of two cases and review of the literature

Two cases are reported in which the growth of an osteoma of the frontal sinuses led to the formation of a secondary lesion, an intracranial mucocele, with marked mass effect.

Spinous process marking: a reliable method for preoperative surface localization of intradural lesions of the high thoracic spine.

Surgical exposure of intradural lesions in the thoracic spine requires intraoperative landmarks to identify the vertebral level. If spinal neuronavigation is not available, the surgeon must rely on alternative localizing methods. Intraoperative fluoroscopy is traditionally used to count the vertebrae throughout the whole spine. In the high thoracic spine, counting the vertebrae is often hampered by the scapular shadows. In these cases, a preoperative marking procedure seems preferable. Magnetic resonance imaging (MRI) based techniques have been increasingly reported, but they share an intrinsic risk of error due to the skin shift occurring at the time of surgery. We describe here a simple technique for unequivocal identification of the vertebral target. In six patients undergoing surgery for intradural lesions of the high thoracic spine, the spinous process of the vertebra corresponding to the lesion was preoperatively identified on an anteroposterior radiograph view and marked infiltrating its tip with a blue dye. At surgery, the vertebral target was identified easily and immediately. No errors occurred. No complications related to the technique were observed. Preoperative marking of the vertebral spinous process with a coloured dye is a simple and unequivocal guide to expose intradural lesions in the high thoracic spine.

Surgical management of orbital cavernous angiomas: Prognosis for visual function after removal

The authors report the outcome of surgical treatment in a group of 25 patients with cavernous angioma of the orbital cavity. In the majority of cases, good esthetic results were appreciable within a few days of surgery. However, the onset or deterioration of preexisting visual deficits, in spite of the complete preservation of the optic nerve in a third of these patients, draws attention to the need for accurate surgical timing.

Surgical Management of Orbital Cavernous Angiomas

The authors report the outcome of surgical treatment in a group of 25 patients with cavernous angioma of the orbital cavity. In the majority of cases, good esthetic results were appreciable within a few days of surgery. However, the onset or deterioration of preexisting visual deficits, in spite of the complete preservation of the optic nerve in a third of these patients, draws attention to the need for accurate surgical timing.

Pituitary apoplexy in an acromegalic woman operated on during pregnancy by transphenoidal approach

We report a rare case of pituitary apoplexy in a woman, acromegalic at the sixth month of pregnancy, who suddenly complained of visual acuity disturbances.

Long-term results of surgical treatment of cerebello-pontine angle epidermoids

SummaryThe long term surgical results in a series of 17 epidermoids of the cerebello-pontine angle are reported. In 11 cases the capsule was removed subtotally and in 6 totally. The absence of mortality among the patients who underwent subtotal removal and the onset of recurrences, if any, only long after the first operation, justify subtotal removal when tight capsular adhesions are present.

Posttraumatic intradiploic leptomeningeal cyst in an adult. Case report

We report the case of an adult with a posttraumatic intradiploic leptomeningeal cyst that caused a circumscribed osteolytic skull lesion. Local pain, the only symptom of the lesion, regressed after surgery. Intradiploic leptomeningeal cysts must be distinguished from intradiploic arachnoid cysts, which are of congenital origin.