Paolo Porcu

Unusual aortic stent complication after endovascular repair of the descending thoracic aorta in type B dissection in a patient with giant-cell arteritis.

The advent of endovascular prostheses to treat descending thoracic aortic lesions offers an alternative approach in patients who are poor candidates for surgery. We present a case of a type B descending thoracic aortic dissection with rapid aneurysmal evolution in a woman with a giant-cell arteritis, treated by endovascular repair: 26 months after, we observed the anterior dislocation of the distal segment of the stent. The dislocation required a second treatment in order to avoid the aortic wall rupture and to restore the axis of the prosthesis. This report emphasizes the difficulty of the endovascular repair in the giant-cell arteritis, because of the vascular fragility confirmed by the rapid aneurysmal evolution after the type B dissection and the appearance of the stenting complication.

Giant aneurysm of the proximal segment of the left anterior descending artery in a patient with Behçet's disease – a combined approach

Behçets disease is an autoimmune, multisystem disease presenting with recurrent oral and genital ulceration as well as ocular involvement. Aneurysmal degeneration of coronary arteries remains a rare phenomenon in Behçets disease. The case of a patient with Behçets disease who presented with severe stenosis of the left anterior descending artery associated with a giant aneurysm of the proximal segment is described. Surgical revascularization was proposed, followed by percutaneous embolization of the aneurysm.

Percutaneous Drainage of Postoperative Pericardial Effusion in Cardiac Surgery

BACKGROUND AND AIM OF THE STUDY  Postoperative pericardial effusion is frequent and can be complicated by cardiac tamponade. Although the different drainage techniques are well described in the setting of medical effusion, there is not a standard postoperative effusion treatment. The aim of this work was to assess the feasibility and effectiveness of the percutaneous pericardial drainage. METHODS This a retrospective study involving 197 patients from 1990 to 2008. Drainage was performed by subxiphoid puncture (91.9%) or left parasternal puncture (8.1%) between 3 and 690 days following a cardiac procedure via median sternotomy. Effusion thickness was at least 10 mm in the subcostal echocardiography view. RESULTS No deaths directly related to the procedure were observed. Complete and enduring drainage was achieved in 158 patients (80.2%). The procedure failed for 22 patients (11.2%) because no fluid was drained in 14 cases (7.1%) and a right ventricular puncture in 8 cases (4.1%). Recurrence of the effusion, which occurred for 17 patients (8.6%), was more frequent if an effusion of more than 5 mm persisted after the first drainage (P = 0.024) and if the drainage was performed outside the operating room because of emergency (P = 0.046). Risk factors for mortality were recurrence of the effusion (P = 0.04) and drainage performed outside the operating room (P = 0.007). CONCLUSIONS Percutaneous pericardial drainage is effective to treat postoperative pericardial effusion. When the effusion is thicker than 10 mm and accessible, it can be the initial strategy and surgical drainage can serve as an alternate strategy in case of failure and complications of this procedure.

Popliteal venous aneurysms: A two center experience with 21 cases and review of the literature

Popliteal venous aneurysms (PVA) are an uncommon but potentially life-threatening disease as they can be a source for pulmonary emboli (PE). We reviewed 21 patients (5 males, 16 females aged 33–79 years, mean age 60 years) with popliteal venous aneurysms treated between 1985 and 1998 in two centers. Nine aneurysms were discovered in patients with varicose veins, and 12 aneurysms were symptomatic: 50% presented with PE and 50% had thrombotic symptoms. The diagnosis of PVA was achieved by venous duplex imaging and phlebography: 85% (18/21) of the aneurysms were saccular and 43% (9/21) had an intraluminal thrombus. Surgical repair was performed by aneurysmectomy with venorrhaphy in 16 patients. Five patients had various procedures, including vein transposition (n=1), resection and end-to-end anastomosis (n=2), resection with interposition vein grafting using the greater saphenous vein (n=1) or superficial femoral vein (n=1). Two patients had a concomitant inferior vena cava filter placement. Mean follow-up was 53 months (range: 2 to 136 months). No operative deaths occured, and no patient had evidence of a recurrent PE. Postoperative thrombosis of the surgical repair developed in 3 cases. Patency was restored with anticoagulation therapy. Four complications (19%) included transistory nerve injury (n=2) and postoperative hematoma (n=2). Despite its rarity PVA should be ruled out in patients with PE and no other obvious embolic source or thromboembolic risk factors. Based on our experience and a review of the literature: (1) Surgical treatment is indicated in all symptomatic patients and tangential aneurysmectomy with lateral venorraphy is the recommended procedure; (2) Asymptomatic patients with saccular or large fusiform PVA should also undergo surgery because of the unpredictable risk of thromboembolic complications; (3) Asymptomatic patients with small fusiform and thrombus-free PVA may remain under close surveillance and surgery should be performed if thrombus is detected in the aneurysm and if thromboembolic complications occur. Although this policy has been advocated by some authors, it will have to be supported by other long-term observations.

Experimental study of sutureless vascular anastomosis with use of glued prosthesis in rabbits.

Objective The objective of this study is to explore the feasibility and efficacy of a new technique for sutureless vascular anastomosis, using glued prosthesis, as a sole anastomosis fixation method in rabbits. Methods Ten rabbits were randomly selected to conduct the experiment. Five rabbits underwent direct anastomosis of infrarenal abdominal aorta, with glued prosthesis. In five other rabbits, reconstruction was done by sutured anastomosis. All animals were immediately examined by echo-Doppler for patency of anastomosis. The burst pressure of the glued anastomosis was measured and compared with that of a sutured artery. The animals were euthanized, and tissue samples were taken for histological examination immediately after the experiment. Results Compared to conventional anastomoses, sutureless vascular anastomoses required shorter time of creation and significantly reduced blood loss (P<5%). There was no significant difference on the average blood flow through the anastomosis between two groups at the end of surgery. All anastomoses with glued prosthesis, examined by echo-Doppler, were patent at the anastomotic site, except one, which was stenosed immediately after surgery. In the control group, except one with stenosis, all conventional anastomoses were patent. Mean burst pressure at the anastomotic site for sutureless anastomoses was lower than in control group. Macroscopically, the BioGlue did not demonstrate any adhesion to the surrounding tissue as it was covered by the vascular prosthesis. Histological examination showed low-grade inflammatory reaction in glued anastomoses versus no inflammatory reaction at the sutured anastomoses. Conclusion This technique may provide a feasible and successful alternative in vascular surgery. However, further long-term studies are necessary to elucidate the break pressure and degree of inflammation at the anastomotic site.

An innovative technique to control bleeding with vacuum device

Bleeding is one of the major problems during surgery as well as in cases of accidental vascular injury. Control of bleeding can be life threatening in two surgical circumstances: when the wound is difficult to expose, and when the tissue too fragile to suture. Following more than 100 animal tests, we developed an innovative vacuum-based suction device, which enables us to address this challenge. We set up a proof-of-concept protocol in humans and report here our first clinical experience.

Post-traumatic injury of the brachiocephalic artery: on-pump beating heart repair.

We report the case of 54 year-old man who presented with an injury of the brachiocephalic artery secondary to a violent blunt chest trauma. The patient underwent urgent open surgical repair. The procedure was achieved on on-pump beating heart approach. The subsequent course was uneventful.

The vascular connector, design of a new device for sutureless vascular anastomosis

BackgroundIn recent years, several methods and new techniques have been studied and proposed for establishment of sutureless vascular anastomoses, streaming use of sutureless vascular surgery in the future.Presentation of the hypothesisThe new vascular connector (NVC) is a hypothetical design of a vascular device, proposed for creation and maintenance of sutureless vascular anastomosis. Implication of NVC would introduce a new device and technique in establishment of sutureless vascular anastomosis in which surgical approach is minimized and so post-operation disorders. It would eliminate need for suture; shorten clampage and operation time, consequently reducing stress for both, the surgeon and the patient. It enables the creation of vascular anastomosis fast, simple, safe, reliable, with satisfactory patency and stability of anastomosis.Testing the hypothesisEfficacy of NVC needs to be evaluated in further studies, in order to be confirmed for clinical use. The effectiveness of NVC should be verified firstly in vitro and in vivo tests; and by animal experiments. The likelihood of its negative influence in thrombogenicity should be well evaluated.Implications of the hypothesisImplication of the new vascular connector (NVC) would be of interest to both patients and the surgeon due to the following main achievements: 1) enables the creation of vascular anastomosis fast and simple, 2) significant shortening of clampage time of blood vessels and operation time-this assumption would be followed by reduced risk of operative and post-operative complications and length of hospital stay or admission to Intensive care unit, 3) safe and reliable, 4) compatible with any blood vessel and standard vascular graft, 5) using the NVC we will reduce in minimum need for replaced blood volume, 6) reduces the cost of treatment. It is anticipated that the NVC would provide shorter operation time and least operative and post-operative complications in creation of sutureless vascular anastomosis.

Haemostasis of a right ventricle-gunshot wound using a novel haemostatic vacuum device

Heart wounds are frequently fatal. The haemorrhage from a right ventricle-gunshot wound in a male patient was successfully controlled using a novel haemostatic vacuum device. This case report shows how this simple, quick and efficient method can be used to control critical bleedings.

Extraction of substernal goitre using an innovative vacuum device

The extraction by cervicotomy of substernal goitres may be impossible and sometimes requires the enlargement of the thoracic inlet with at least a sternal-split. We present the extraction of a posterior mediastinal substernal goitre with the application of an innovative vacuum-based suction device, previously used for the control of bleeding from the heart and great vessels in clinical and experimental conditions.