Paolo Trabucco

Corneal wound healing after laser vision correction

Any trauma can trigger a cascade of responses in tissues, with the purpose of safeguarding the integrity of the organ affected by the trauma and of preventing possible damage to nearby organs. Subsequently, the body tries to restore the function of the organ affected. The introduction of the excimer laser for keratorefractive surgery has changed the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. In recent years, with the increased understanding of the basic science of refractive errors, higher-order aberrations, biomechanics, and the biology of corneal wound healing, a reduction in the surgical complications of keratorefractive surgery has been achieved. The understanding of the cascade of events involved in the corneal wound healing process and the examination of how corneal wound healing influences corneal biomechanics and optics are crucial to improving the efficacy and safety of laser vision correction.

Genetic Analysis for Two Italian Siblings with Usher Syndrome and Schizophrenia

Usher syndrome is a group of autosomal recessive genetic disorders characterized by deafness, retinitis pigmentosa, and sometimes vestibular areflexia. The relationship between Usher syndrome and mental disorders, most commonly a “schizophrenia-like” psychosis, is sometimes described in the literature. The etiology of psychiatric expression of Usher syndrome is still unclear. We reported a case of two natural siblings with congenital hypoacusis, retinitis pigmentosa, and psychiatric symptoms. Clinical features and genetic analysis were also reported. We analyzed possible causes to explain the high prevalence of psychiatric manifestations in Usher syndrome: genetic factors, brain damage, and “stress-related” hypothesis.

Microperimetric biofeedback in a patient with oculocutaneous albinism

mechanical cross talk, or normal or abnormal extraocularmuscle dynamics. This case report is the first evidence reported to date of the potential applicability and utility of MP in nystagmus. Based on the retinal projection of the fixation pattern, MAIA MP may be useful to quantify the pattern of fixation in nystagmus and to recognize the dominant eye attending to the higher fixation stability value and the comparison of the extent of the ellipse of fixation between eyes. Future studies should evaluate this potential applicability of MP in case series of nystagmus, as well as the agreement with the measurements obtained with video-oculography.