Patricia Tippett

ISBT Working Party on Terminology for Red Cell Surface Antigens: Munich Report

The ISBT Working Party on Terminology for Red Cell Surface Antigens was established in 1980 under the chairmanship of Dr. F.H. Allen, Jr., to devise a numerical nomenclature suitable for computerization. The intent is to provide a standard terminology for those who care to use it, not to replace existing alphabetical symbols. The Working Party is also charged with maintaining uniformity in alphabetical designations. The initial meeting of the Working Party was held in Montreal on August 16th, 1980, and a second meeting convened in New York on October 29th, 1981; the decisions to give high priority to assignment of numbers for each of the blood group specificities, to the avoidance of superscripts and subscripts in designations of new specificities, and to the use of capital letters of the Latin alphabet, were unanimous [l]. Subcommittees were formed to deal with the various blood group systems and unassigned low and high incidence antigens separately. This report is a compilation of the recommendations made by the subcommittees and accepted by the Working Party at the Budapest meeting on August lst, 1982 [2] and at the Munich meeting on July 21st, 1984.

Data for X-mapping calculations, Israeli families tested for Xg, g-6-pd and for colour vision

The results are recorded of tests for the X‐linked red cell antigen Xga on families with glucose‐6‐phosphate dehydrogenase deficient members. The families live in Israel and belong to Kurdish, Iraqi, Yemenite, Sefardic and Ashkenazy Communities.

Linkage relations of X‐borne ichthyosis to the Xg blood groups and to other markers of the X in Israelis

A series of families in the counties around Oxford (Kerr, Wells & Sanger, 1964) gave the first indication that there was reasonably close linkage between the Xg blood groups and the X-borne type of ichthyosis. This stimulated the investigation in Israel of which the present paper gives the full account (it includes the data of an interim report by Adam et al. 1966). The Oxford findings also stimulated a survey based on London (Wells et al. 1966). These three publications established beyond any doubt that the locus for Xg is close to that for ichthyosis. The survey in Israel included tests for glucose-6-phosphate dehydrogenase (g-6-pd) aa well as for colour vision.

X‐linked ichthyosis: linkage relationship with the Xg blood groups and other studies in a large Dutch kindred

Three propositi with probable X-linked ichthyosis were found from the files of the Dermatology Department of the Binnengasthuis (University Hospital, Amsterdam). These propositi and some of their relatives were seen at the Dermatology Clinic and they, together with the files of the Civil Registration Office, provided complete pedigrees. Preliminary tests showed the family of one of the propositi not to be informative with regard to the main purpose of the investigation : all those tested were Xg (a + ) and the mother, who is dead, had come from Germany. The other two propositi were both thought to have had an Italian great-great-great-grandfather and subsequently, as a result of the investigation, were shown to belong to one large kindred.

The Lu(a-b-) Syndrome and an Apparent Upset of P1 Inheritance

Abstract. The inhibitor gene responsible for the dominant form of Lu(a‐b‐), called In(Lu), which also inhibits Aua, i and P1, was the cause of an apparent upset in the rules of inheritance of the P system. The same Sardinian kindred also shows In(Lu)to be genetically independent of the P and Yt loci.